Adaptation and validation of the Claremont Purpose Scale to measure Chinese adolescents' purpose in life.

Despite purpose measures being developed for adolescents, quantitative research investigating purposes prior to late adolescence and in non-Western societies remains nascent. This study evaluated the psychometric soundness of the Claremont Purpose Scale among Chinese adolescents. An initial prestudy (n = 34) was conducted to ensure linguistic equivalence. Subsequently, Study 1 (n = 1691) assessed the scale's reliability and factor structure, also investigating its functional equivalence across gender, adolescence stages, and language versions at the item level. Study 2 (n = 7842) investigated the scale's construct, convergent, predictive, and incremental validity, as well as tested for the scale's measurement invariance across different groups at the scale level. The results support the scale's use as a tool for researchers and practitioners to understand and cultivate purpose in adolescents.

Timing Matters: A Longitudinal Study Examining the Effects of Physical Activity Intensity and Timing on Adolescents' Mental Health Outcomes.

Physical activity is universally acknowledged for its benefits to mental health; however, the specific intensities and timings that best benefit adolescents' mental health, crucial due to their significant influence on daily schedules, have not been thoroughly investigated. This study addresses the substantive research gap by exploring the varied effects of physical activity intensity (light versus moderate to vigorous) and timing (weekdays versus weekends and holidays) on adolescent mental health. Utilizing a large-scale longitudinal dataset (NT1 = 84,054; NT2 = 44,623) from 158 schools, this research describes the current state of adolescent physical activity and investigates the effects of physical activity on mental health outcomes, including positive (i.e., life satisfaction, positive mental health) and negative indicators (depression, anxiety), over a 6-month period. Participants were adolescents aged 9-19 years (mean age = 12.73 ± 2.43 years, 48.9% female), with the analysis adjusted for potential confounding factors. Results showed that as adolescents grow older, their engagement in moderate-to-vigorous physical activity during both weekdays and weekends/holidays tends to decrease, while light physical activity during weekdays increases. Multilevel regression analysis indicated that moderate-to-vigorous physical activity during weekends/holidays at Time 1 positively correlated with better mental health outcomes at Time 2 (six months later), featuring enhanced positive indicators and reduced negative ones. Moderate-to-vigorous physical activity on weekdays at Time 1 was positively linked to mental health at Time 2. Light physical activity during weekends/holidays at Time 1 positively predicted life satisfaction and positive mental health at Time 2. In contrast, light physical activity on weekdays at Time 1 negatively correlated with life satisfaction at Time 2. The study underscores the importance of promoting moderate-to-vigorous physical activity, particularly on weekends and holidays, to improve mental health outcomes among adolescents.

Effect of Hydrogen-Consuming Compounds on In Vitro Ruminal Fermentation, Fatty Acids Profile, and Microbial Community in Water Buffalo.

The present study aimed to investigate the effect of hydrogen-consuming compounds on ruminal methane (CH4) production, in vitro fermentation parameters, fatty acids profile, and microbial community in water buffalo. Different sodium nitrate to disodium fumarate ratios [2:1 (F), 1:1 (S), 1:2 (T)] were studied in vitro by batch culture technique in the presence of linoleic acid. Results revealed that the dominant bacterial communities were not affected with sodium nitrate and disodium fumarate, whereas CH4 production and Verrucomicrobia, Succiniclasticum, norank_f__Muribaculaceae, and Prevotellaceae_UCG-003 were reduced (P < 0.05). However, ruminal pH, unsaturated fatty acids/saturated fatty acids (UFA/SFA) and Campilobacterota, Selenomonas, Succinivibrio, Oribacterium, Christensenellaceae_R-7_group, Campylobacter, Shuttleworthia, Schwartzia, and Prevotellaceae_YAB2003_group were increased (P < 0.05). Total volatile fatty acids (TVFA) and Spirochaetae, Fibrobacterota, Verrucomicrobia, Fibrobacter, Treponema, and Prevotellaceae were decreased in F (P < 0.05), but cis-9, trans-11CLA, acetate/propionate and Proteobacteria, Campilobacterota, Selenomonas, Succinivibrio, and Campylobacter were increased in F (P < 0.05). The highly selected bacterial genera in F were Campylobacter and Succinivibrio. The disodium fumarate, enhanced (P < 0.05) the TVFA, propionate, total bacteria, Butyrivibrio proteoclasticus, and Atypical butyrivibrio. The concentrations of C18:3n3, C20:3n6, C21:0, C22:2n6, and C22:1n9, as well as the populations of total fungi, protozoa, methanogens, Butyrivibrio hungatei in T were higher (P < 0.05). The highly selected bacterial genera in T were Fibrobacter and Treponema. Conclusively, the addition of sodium nitrate and disodium fumarate can reduce the CH4 production and optimize ruminal fatty acid composition. Furthermore, disodium fumarate can alleviate the adverse effect of sodium nitrate on the rumen fermentation.

Self-control protects Tibetan adolescent orphans from mental problems: A mediating role of self-esteem.

INTRODUCTION: Orphans are usually adopted by eligible families or raised by the government and organizations mutually. Although their basic needs are taken care of, the absence of parents in life makes orphans face higher risks of mental health problems, such as anxiety and depression, leading to lower levels of self-esteem and happiness. Previous studies have shown that self-control may have an effect on improving self-esteem; thus, it could become a way to protect mental health. Building on the structural equation model, the current study tested the possible effects of self-control on levels of self-esteem and mental problems among Tibetan orphans. METHODS: Participants were 143 adolescents from age 16 to 22 years (Mage = 18.77, 54.8% female) from an institutionalized orphanage in Tibet and they completed questionnaires measuring self-esteem, self-control, and clinical symptoms (Symptom Checklist-90-Revised). RESULTS AND CONCLUSIONS: Self-control was negatively associated with psychological illness through improved self-esteem. The present study suggested that self-control was a protective factor for the mental health of adolescent orphans through influencing the levels of self-esteem. Limitations and future directions were discussed.

Seeking the "Beauty Center" in the Brain: A Meta-Analysis of fMRI Studies of Beautiful Human Faces and Visual Art.

During the past two decades, cognitive neuroscientists have sought to elucidate the common neural basis of the experience of beauty. Still, empirical evidence for such common neural basis of different forms of beauty is not conclusive. To address this question, we performed an activation likelihood estimation (ALE) meta-analysis on the existing neuroimaging studies of beauty appreciation of faces and visual art by nonexpert adults (49 studies, 982 participants, meta-data are available at https://osf.io/s9xds/ ). We observed that perceiving these two forms of beauty activated distinct brain regions: While the beauty of faces convergently activated the left ventral striatum, the beauty of visual art convergently activated the anterior medial prefrontal cortex (aMPFC). However, a conjunction analysis failed to reveal any common brain regions for the beauty of visual art and faces. The implications of these results are discussed.

Enhancing the Robustness of Smartphone Photoplethysmography: A Signal Quality Index Approach.

Heart rate variability (HRV) provides essential health information such as the risks of heart attacks and mental disorders. However, inconvenience related to the accurate detection of HRV limits its potential applications. The ubiquitous use of smartphones makes them an excellent choice for regular and portable health monitoring. Following this trend, smartphone photoplethysmography (PPG) has recently garnered prominence; however, the lack of robustness has prevented both researchers and practitioners from embracing this technology. This study aimed to bridge the gap in the literature by developing a novel smartphone PPG quality index (SPQI) that can filter corrupted data. A total of 226 participants joined the study, and results from 1343 samples were used to validate the proposed sinusoidal function-based model. In both the correlation coefficient and Bland-Altman analyses, the agreement between HRV measurements generated by both the smartphone PPG and the reference electrocardiogram improved when data were filtered through the SPQI. Our results support not only the proposed approach but also the general value of using smartphone PPG in HRV analysis.

Happiness at Your Fingertips: Assessing Mental Health with Smartphone Photoplethysmogram-Based Heart Rate Variability Analysis.

Background: Heart rate variability (HRV) provides essential mental health information for clinical diagnosis, telemedicine, preventive medicine, and public health; however, the lack of a convenient detection method limits its potential. Objective: This study aims to investigate the feasibility and credibility of smartphone photoplethysmogram (PPG)-based HRV analysis for mental well-being and health assessment. Methods: Data were collected from 93 students and university employees in Shenzhen, China. Forty-six percent were male, and the average age was 23.71 years (σ = 4.33). An app recorded a 4-min video of their fingertips and converted the frames into five HRV measures, including the root mean square of successive differences (rMSSD), standard deviation of the normal-to-normal (NN) intervals (SDNN), percentage of successive NN intervals differing by ≥50 ms (pNN50), log high-frequency (HF) HRV, and log low-frequency (LF) HRV. Results: The data verify the positive relationship between mental well-being and HRV measures. Participants with higher Satisfaction With Life Scale (SWLS) scores have a higher rMSSD (p = 0.047), SDNN (p = 0.009), log HF (p = 0.02), and log LF (p = 0.003). Participants who suffer from depression have lower log HF (p = 0.048) and log LF (p = 0.02). Participants in the high-anxiety group have lower pNN50 (p = 0.04) and log HF (p = 0.03). Conclusions: The results of this study validate the feasibility of using the smartphone PPG by demonstrating similar results to previous findings. Our data also support the theorized positive link between mental health and HRV.

The Neural Basis of Independence Versus Interdependence Orientations: A Voxel-Based Morphometric Analysis of Brain Volume.

Sociocultural research has established independence and interdependence as two fundamental ways of thinking about oneself and the social world. Recent neuroscience studies further demonstrate that these orientations modulate brain activity in various self- and socially related tasks. In the current study, we explored whether the traits of independence and interdependence are reflected in anatomical variations in brain structure. We carried out structural brain imaging on a large sample of healthy participants ( n = 265) who also completed self-report questionnaires of cultural orientations. Voxel-based morphometry analysis demonstrated that a relative focus of independence (vs. interdependence) was associated with increased gray-matter volume in a number of self-related regions, including ventromedial prefrontal cortex, right dorsolateral prefrontal cortex, and right rostrolateral prefrontal cortex. These results provide novel insights into the biological basis of sociocultural orientations.

Visuomotor control in continuous response time tasks across different age groups.

The goal was to examine whether visuomotor control and choice response time shared age-related developmental trajectories, and if prior computer experience played an important role in control processes. Children (6-7, 8-9, 10-11 yr.), younger adults (24 yr.) and older adults (76 yr.) performed the cursor pointing and choice response time (CRT) tasks with a computer mouse. Participants moved the mouse cursor back and forth to click two targets on the screen as fast and accurately as possible. In the CRT, based on visual stimuli, participants moved and clicked one of the three targets on the screen as fast and accurately as possible; the time between stimulus onset and clicking the correct target was recorded as the choice response time. Visuomotor performance increased with age to younger adulthood but was worse in the older adult group. CRT performance was also positively related to age among the groups of children, with scores leveling off in the young adult group. Computer experience was statistically significantly related only to visuomotor control, but not to CRT. Optimal CRT performance required only sub-optimal visuomotor control. Cognitive and sensory age declines may be related to the poorer CRT performance in the oldest age group.

Seeing is more than believing: Personal experience increases climate action.

Although global warming is a serious problem that influences numerous people worldwide, individuals are still reluctant to change their behaviours. The present research investigates how local hot temperatures affect climate action in non-Western groups. In Study 1, an analysis of temperature and information acquisition by Shanghai residents in 122 days found that heat increased attention and awareness of climate change. In Study 2 and Study 3, participants who were primed with heat-related perceptions were more likely to take climate action in private and public spheres. In Study 4, we further identified that people who experienced hot temperature events increased their beliefs and efficacy about climate change, which in turn motivated them to take more climate action. Importantly, the mediating effects were significant both in the manipulation of heat and real-world settings. Consistent with our theoretical perspective, seeing is more than believing because personal experience increases climate action by fostering climate change beliefs and efficacy.

Global burden of major depressive disorders attributable to intimate partner violence against women: Magnitude, temporal trends, and regional inequalities.

AIMS: This study aimed to analyze the temporal trends, spatial heterogeneities, and potential improvements in the burden of major depressive disorders (MDD) attributable to intimate partner violence (IPV) against women across 21 global burden of disease (GBD) regions, and 204 countries and territories from 1990 to 2019. METHODS: We evaluated the burden of MDD attributable to IPV against women, as measured in disability-adjusted life years (DALYs) per 100,000 people across 21 GBD regions and 204 GBD countries and territories, using data from the 2019 GBD Study. The average annual percentage change (AAPC) of the DALY age-standardized rates (ASRs) was used to reflect trends over time. LOESS and quantile regression were used to model the relationship between the five GBD sociodemographic index (SDI) categories and DALY ASRs. Frontier analysis determined the minimum achievable DALY ASR associated with developmental status, as measured by the SDI. RESULTS: The overall AAPC in age-standardized DALY rates for MDD attributable to IPV declined globally between 1990 and 2019. Despite the overall global decline (AAPC -0.08 [95 % UI -0.2, 0.03]), certain GBD regions, particularly high-income North America and Central Latin America, have experienced increases in DALY ASRs. The relationship between SDI and MDD burden showed a U-shaped variability, with low-SDI regions consistently exhibiting higher and stable DALY rates. Frontier analysis revealed that several countries, regardless of their SDI, have substantial gaps between observed and potentially achievable DALY rates, indicating areas for targeted intervention to reduce the burden of MDD due to IPV. CONCLUSIONS: Significant spatial and temporal heterogeneity in MDD due to IPV was observed globally from 1990 to 2019, highlighting the substantial potential for improvement in various countries. Protective measures should be customized to suit the unique cultural contexts, developmental statuses, and regional disparities of each country.

Risk and prosocial behavioural cues elicit human-like response patterns from AI chatbots.

Emotions, long deemed a distinctly human characteristic, guide a repertoire of behaviors, e.g., promoting risk-aversion under negative emotional states or generosity under positive ones. The question of whether Artificial Intelligence (AI) can possess emotions remains elusive, chiefly due to the absence of an operationalized consensus on what constitutes 'emotion' within AI. Adopting a pragmatic approach, this study investigated the response patterns of AI chatbots-specifically, large language models (LLMs)-to various emotional primes. We engaged AI chatbots as one would human participants, presenting scenarios designed to elicit positive, negative, or neutral emotional states. Multiple accounts of OpenAI's ChatGPT Plus were then tasked with responding to inquiries concerning investment decisions and prosocial behaviors. Our analysis revealed that ChatGPT-4 bots, when primed with positive, negative, or neutral emotions, exhibited distinct response patterns in both risk-taking and prosocial decisions, a phenomenon less evident in the ChatGPT-3.5 iterations. This observation suggests an enhanced capacity for modulating responses based on emotional cues in more advanced LLMs. While these findings do not suggest the presence of emotions in AI, they underline the feasibility of swaying AI responses by leveraging emotional indicators.

Culture and Awe: Understanding Awe as a Mixed Emotion.

Recent work is establishing awe as an important positive emotion that offers physical and psychological benefits. However, early theorizing suggests that awe's experience is often tinged with fear. How then, do we reconcile emergent positive conceptualizations of awe with its more fearful elements? We suggest that positive conceptualizations of awe may partially reflect modern Western experiences of this emotion, which make up the majority of participant samples when studying awe. To test whether awe contains more fearful qualities outside of Western cultures, we compared participants' experiences of this emotion in China to those in the United States. In a two-week daily diary study (Study 1), Chinese participants reported greater fear than American participants during experiences of awe, but not a comparison positive emotion. In response to a standardized awe induction (Study 2), Chinese participants reported more fear, whereas American participants reported more positive emotions. Physiological changes in autonomic activity differed by culture only for heart rate, but not skin conductance or respiratory sinus arrhythmia. These findings reveal that awe may be experienced as a more fearful, mixed emotion in China than in the United States and suggest that current positive conceptualizations of awe may reflect a disproportionate reliance on modern Western samples. Supplementary Information: The online version contains supplementary material available at 10.1007/s42761-024-00243-3.

AI Experience Predicts Identification with Humankind.

Artificial intelligence is becoming a potential outgroup of humans, which, according to social identity theory, may make humanity more salient. To explore how identification with humankind correlates to being exposed to artificial intelligence, we developed an AI Experience Questionnaire to measure this relationship and demonstrated that AI experience positively predicted human identity (Study 1a, N = 806). This correlation held when controlling for AI threats, educational level, international mobility experience, gender, and age (Study 2, N = 981, Mage = 27.55 ± 6.74; 448 males, 533 females). Study 1a also demonstrated that AI awareness-consisting of perceived anthropomorphism and perceived proximity-mediated the relationship between AI experience and human identity. This mediation model was replicated half a year later (Study 1b, N = 886). Moreover, a moderation analysis demonstrated that for both Easterners and Westerners, the correlation between AI experience and human identity was significantly positive; however, Western culture amplified the correlation (Study 3; N = 177, Mage = 32.35 ± 10.99; 90 Easterners, 87 Westerners). To conclude, persons with more AI experience may be more inclined to perceive AI as an outgroup of humans, and therefore AI experience positively predicts identification with humankind.

Mindfulness Practice versus Physical Exercise in Enhancing Vitality.

Vitality is important for subjective well-being and performance, which makes strategies for its enhancement an important research issue. While prior research showed that mindfulness practice and physical exercise are both effective at enhancing vitality, no study has compared their efficacy. This study aimed to address this issue. Seventy-one Chinese adults participated in the study and were randomized to one of the intervention groups, i.e., mindfulness practice or physical exercise. The mindfulness practice group completed guided mindfulness trainings, while the physical exercise group completed self-chosen aerobic trainings for seven days. The levels of vitality and its four factors at three time points (baseline, post-intervention, 7-day follow-up) were measured and compared. Compared with physical exercise, mindfulness practice showed stronger effects in enhancing vitality and maintaining the improvements. The findings suggest that guided mindfulness practice is more effective than self-chosen aerobic physical exercise at enhancing vitality and maintaining its improvements.

Social media use, uncertainty, and negative affect in times of pandemic crisis.

Objective: A common assertion in the social media literature is that passive media use undermines affective wellbeing, and active media use enhances it. The present study investigated the effects of social media use on negative affective wellbeing during pandemic crises and examined the mechanism underlying these effects through perceived uncertainty. Methods: Three studies were conducted during the Delta variant phase in the post-peak period of the COVID-19 pandemic in China. Participants were recruited from the medium-high-risk infection areas in late August 2022. Study 1 used a cross-sectional survey to explore the relationships between social media use, uncertainty, and negative affect during the pandemic crisis. Study 2 employed a repeated-measures experiment to demonstrate how social media use and (un)certainty impact negative affect. Study 3 utilized a one-week experience sampling design to examine the role of uncertainty in the relationship between social media use and negative affect in real life. Results: Despite some inconsistencies regarding social media use's direct effect on negative affect, across the three studies, perceived uncertainty was critical in linking pandemic-related social media use to individuals' negative affect, particularly for passive use. Conclusions: The relationships between social media use and affective wellbeing are complex and dynamic. While the perception of uncertainty provided an underlying mechanism that links social media use to individuals' affective wellbeing, this mechanism may be further moderated by individual-level factors. More research is needed as we seek to understand how social media use impacts affective wellbeing in uncertain contexts.

Effects of a self-affirmation intervention among Chinese adolescents during the COVID-19 pandemic: A large-scale randomized controlled trial.

The COVID-19 pandemic, characterized by its highly contagious nature and devastating death toll, posed a dual threat to both physical and psychological well-being. As a potential intervention to alleviate the psychological impact, values-affirmation involves individuals engaging in the activity of writing about their core values. While its effectiveness in non-WEIRD (i.e. Western, Educated, Industrialized, Rich, Democratic) populations, notably among Chinese adults, has been confirmed, it remains largely unexplored whether the intervention can promote mental health in Chinese adolescents, especially in the context of the COVID-19 pandemic. The purpose of this study thus is to provide the first empirical evaluation of this intervention in promoting well-being and alleviating psychological distress among Chinese adolescents during the COVID-19 pandemic. A total of 2,234 students from 112 secondary schools in China were randomly assigned to an affirmation or control condition. The study found that self-affirmation intervention improved students' life satisfaction, mental health, and self-esteem, as well as buffered a decline of their purpose in life; however, no effects were found for clinical measures of depression, anxiety, and loneliness. The results suggest that self-affirmation interventions, while having limited effects on clinically relevant outcomes, can be an effective approach to boost well-being in adolescents during a major crisis, including in a more historically collectivist culture. Implications for self-affirmation theory and cultural psychology, as well as avenues for future research, are discussed.

Fear during pandemic promoted holistic cognitive style: The moderating role of uncertainty.

The present study explored the link between fear and holistic cognitive style and the moderating role of uncertainty. We examined these effects in a real-life situation: the long-term, global COVID-19 pandemic, which provided a natural context of fear and uncertainty. The current study comprises three studies recruiting N = 1,310 participants. Study 1 compared the link between fear and holistic style in the United States (a relatively uncertain situation presented by the COVID-19 pandemic) and China (a pandemic situation with relative certainty) in the early days of the pandemic. Study 2 examined the moderation effect of uncertainty in the relationship between fear and holistic style by manipulating participants into a fearful (vs. control) condition. Study 3 employed a longitudinal design to demonstrate the effect of fear-related emotions on holistic style change over a 3-month period. Across three studies, the moderation effect of uncertainty in the relationship between fear-related emotions and holistic style during the COVID-19 pandemic was consistently observed. In sum, this study provided an ecological and explanatory mechanism for understanding the impact of individuals' fear on holistic cognitive style. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Effects of mixed sugarcane tops and napiergrass silages on fermentative quality, nutritional value, and milk yield in water buffaloes.

The objective of this study was to evaluate the effects of sugarcane tops (STs) and napiergrass (NG) silage on fermentative quality, nutritional value and milk yield in water buffaloes. Silage were prepared either conventionally without ST (C) or mixed with 25% (S1), 50% (S2), and 75% (S3) ST based on fresh matter. Twenty-eight lactating buffaloes were divided into four groups with seven replicates and fed four experimental diets containing the corresponding silages. The S3 silage fermented well with a higher (P < 0.05) lactic acid content and lower (P < 0.05) pH and ammonia-N level than those of other mixed silage. Silage with increasing ST proportions showed a significant increase (P < 0.05) in the apparent digestibility of dry matter, crude protein, organic matter, and gross energy. As a result, water buffalo fed S3 silage increased dry matter intake (P < 0.05) and tended to have higher milk yield and feed efficiency as compared with the C group. Our study indicates that adding ST improves NG silage fermentation and enhances the nutrient digestibility and milk production in water buffaloes, and mixing ratio of 25%NG and 75%ST had the highest lactate fermentation quality and presented a high feed value.

Assessment of Factors Associated With Mental Well-Being Among Chinese Youths at Individual, School, and Province Levels.

Importance: Although rapid urbanization in China provided improved economic prosperity and educational opportunities, it was associated with increased internalizing and externalizing problems among youths, with negative outcomes for mental well-being. Previous studies suggested that factors in individual, school, and regional levels were associated with mental well-being, and comprehensively examining these factors may provide evidence for policies for improving youth mental health. Objective: To investigate factors associated with mental well-being at individual, school, and province levels among Chinese youths. Design, Setting, and Participants: This cross-sectional study analyzed nationally representative data collected December 1, 2021, to January 1, 2022, from schools in China. Among 435 schools, 144 institutions had primary school students, 107 institutions had middle school students, 95 institutions had primary and middle school students, and 89 institutions had high school students. A total of 398 520 students were included. Exposures: Characteristics at individual, school, and province levels. Main outcomes and measures: The main outcome was mental well-being, assessed by the Short Warwick-Edinburgh Mental Well-being Scale. Linear mixed-effects models were used to investigate individual, school, and regional disparities in mental well-being among youths. Results: There were 398 520 participants (194 460 females [48.80%]; mean [SD; range] age, 13.78 [2.40; 9-20] years). At the school level, 352 443 students (88.44%) were in public school and 291 354 students (73.11%) were in urban schools. Drinking (coefficient = -1.08; 95% CI, -1.12 to -1.05; P < .001), smoking (coefficient = -0.89; 95% CI, -0.96 to -0.83; P < .001), and increased age (coefficient per 1-year increase in age = -0.02; 95% CI, -0.03 to -0.01; P < .001) were associated with worse mental well-being. Male sex (coefficient = 1.01; 95% CI, 0.98 to 1.04; P < .001), being in a 1-child family (coefficient = 0.17; 95% CI, 0.13 to 0.20; P < .001), being in the Han group (coefficient vs other ethnic groups = 0.20; 95% CI, 0.14 to 0.26; P < .001), a higher frequency and coverage of psychological courses (eg, ≥2/wk for all students vs none: coefficient = 1.02; 95% CI, 0.36 to 1.69; P = .003), and a higher level of self-rated popularity in school (coefficient per 1-unit increase in score = 0.89; 95% CI, 0.88 to 0.89; P < .001) were associated with improved mental well-being. However, age (eg, age and 1 courses/2 wk for all students: coefficient per 1-year increase in age = -0.047; 95% CI, -0.089 to -0.005; P = .03) and sex (eg, female sex and ≥2 courses/wk for some students: coefficient = -0.184; 95% CI, -0.323 to -0.046; P = .009) had interactions with the association between psychological courses and mental well-being. Conclusions and relevance: This study found that social disparities in mental well-being existed and that various factors at different levels were associated with mental well-being among Chinese youths. These findings suggest that public mental health programs may be recommended for associated improvements in regional disparities in mental health resources.