Detalhe da pesquisa
1.
Single nucleotide polymorphisms of cytokine-related genes and association with clinical outcome in a Chagas disease case-control study from Brazil.
Mem Inst Oswaldo Cruz
; 113(6): e170489, 2018 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29768622
2.
Priming astrocytes with TNF enhances their susceptibility to Trypanosoma cruzi infection and creates a self-sustaining inflammatory milieu.
J Neuroinflammation
; 14(1): 182, 2017 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28877735
3.
A human type 5 adenovirus-based Trypanosoma cruzi therapeutic vaccine re-programs immune response and reverses chronic cardiomyopathy.
PLoS Pathog
; 11(1): e1004594, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25617628
4.
CD8+ T-cells expressing interferon gamma or perforin play antagonistic roles in heart injury in experimental Trypanosoma cruzi-elicited cardiomyopathy.
PLoS Pathog
; 8(4): e1002645, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22532799
5.
Levels of circulating anti-muscarinic and anti-adrenergic antibodies and their effect on cardiac arrhythmias and dysautonomia in murine models of Chagas disease.
Parasitology
; 141(13): 1769-78, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25093253
6.
Tumor necrosis factor is a therapeutic target for immunological unbalance and cardiac abnormalities in chronic experimental Chagas' heart disease.
Mediators Inflamm
; 2014: 798078, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25140115
7.
Severity of chronic experimental Chagas' heart disease parallels tumour necrosis factor and nitric oxide levels in the serum: models of mild and severe disease.
Mem Inst Oswaldo Cruz
; 109(3): 289-98, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24937048
8.
Treatment with benznidazole and pentoxifylline regulates microRNA transcriptomic profile in a murine model of Chagas chronic cardiomyopathy.
PLoS Negl Trop Dis
; 17(3): e0011223, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36972298
9.
Genetic Ablation and Pharmacological Blockade of Bradykinin B1 Receptor Unveiled a Detrimental Role for the Kinin System in Chagas Disease Cardiomyopathy.
J Clin Med
; 12(8)2023 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37109224
10.
Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions.
Brain Behav Immun
; 26(7): 1136-49, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22841695
11.
Pro-Inflammatory Profile of Children Exposed to Maternal Chikungunya Virus Infection during the Intrauterine Period: A One-Year Follow-Up Study.
Viruses
; 14(9)2022 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36146688
12.
Treatment With Suboptimal Dose of Benznidazole Mitigates Immune Response Molecular Pathways in Mice With Chronic Chagas Cardiomyopathy.
Front Cell Infect Microbiol
; 11: 692655, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34381739
13.
CCL3/Macrophage Inflammatory Protein-1α Is Dually Involved in Parasite Persistence and Induction of a TNF- and IFNγ-Enriched Inflammatory Milieu in Trypanosoma cruzi-Induced Chronic Cardiomyopathy.
Front Immunol
; 11: 306, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32194558
14.
Chronic Trypanosoma cruzi-elicited cardiomyopathy: from the discovery to the proposal of rational therapeutic interventions targeting cell adhesion molecules and chemokine receptors--how to make a dream come true.
Mem Inst Oswaldo Cruz
; 104 Suppl 1: 226-35, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19753478
15.
Trypanosoma cruzi activates mouse cardiac fibroblasts in vitro leading to fibroblast-myofibroblast transition and increase in expression of extracellular matrix proteins.
Parasit Vectors
; 11(1): 72, 2018 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29382361
16.
Genetic Polymorphism at CCL5 Is Associated With Protection in Chagas' Heart Disease: Antagonistic Participation of CCR1+ and CCR5+ Cells in Chronic Chagasic Cardiomyopathy.
Front Immunol
; 9: 615, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29696014
17.
Integration of miRNA and gene expression profiles suggest a role for miRNAs in the pathobiological processes of acute Trypanosoma cruzi infection.
Sci Rep
; 7(1): 17990, 2017 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29269773
18.
TNF-α and TNFR in Chagas disease: from protective immunity to pathogenesis of chronic cardiomyopathy.
Adv Exp Med Biol
; 691: 221-30, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21153326
19.
Pentoxifylline reverses chronic experimental Chagasic cardiomyopathy in association with repositioning of abnormal CD8+ T-cell response.
PLoS Negl Trop Dis
; 9(3): e0003659, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25789471
20.
MicroRNA Transcriptome Profiling in Heart of Trypanosoma cruzi-Infected Mice: Parasitological and Cardiological Outcomes.
PLoS Negl Trop Dis
; 9(6): e0003828, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26086673