Detalhe da pesquisa
1.
Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis.
Proc Natl Acad Sci U S A
; 118(19)2021 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33941676
2.
The incidence of movement disorder increases with age and contrasts with subtle and limited neuroimaging abnormalities in argininosuccinic aciduria.
J Inherit Metab Dis
; 2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38044746
3.
TNF receptor 2 signaling prevents DNA methylation at the Foxp3 promoter and prevents pathogenic conversion of regulatory T cells.
Proc Natl Acad Sci U S A
; 116(43): 21666-21672, 2019 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31597740
4.
The exosome journey: from biogenesis to uptake and intracellular signalling.
Cell Commun Signal
; 19(1): 47, 2021 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33892745
5.
Ascending Vaginal Infection Using Bioluminescent Bacteria Evokes Intrauterine Inflammation, Preterm Birth, and Neonatal Brain Injury in Pregnant Mice.
Am J Pathol
; 188(10): 2164-2176, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30036519
6.
Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy.
Mol Ther
; 25(8): 1790-1804, 2017 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28550974
7.
IRF5 controls both acute and chronic inflammation.
Proc Natl Acad Sci U S A
; 112(35): 11001-6, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26283380
8.
mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria.
Sci Transl Med
; 16(729): eadh1334, 2024 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38198573
9.
IRF5 is a specific marker of inflammatory macrophages in vivo.
Mediators Inflamm
; 2013: 245804, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24453413
10.
Ex vivo precision-cut liver slices model disease phenotype and monitor therapeutic response for liver monogenic diseases.
F1000Res
; 12: 1580, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38618017
11.
Assessment of Pre-Clinical Liver Models Based on Their Ability to Predict the Liver-Tropism of Adeno-Associated Virus Vectors.
Hum Gene Ther
; 34(7-8): 273-288, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36927149
12.
Clinical applications for exosomes: Are we there yet?
Br J Pharmacol
; 178(12): 2375-2392, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33751579
13.
Re-structuring lentiviral vectors to express genomic RNA via cap-dependent translation.
Mol Ther Methods Clin Dev
; 20: 357-365, 2021 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33553484
14.
Safety and efficacy of an engineered hepatotropic AAV gene therapy for ornithine transcarbamylase deficiency in cynomolgus monkeys.
Mol Ther Methods Clin Dev
; 23: 135-146, 2021 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34703837
15.
Beclin-1-mediated activation of autophagy improves proximal and distal urea cycle disorders.
EMBO Mol Med
; 13(2): e13158, 2021 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33369168
16.
Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism.
Sci Transl Med
; 13(594)2021 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34011628
17.
Gene therapy for inherited metabolic diseases.
J Mother Child
; 24(2): 53-64, 2020 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33554501
18.
Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload.
Cell Death Differ
; 27(5): 1588-1603, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31685979
19.
Correction: Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload.
Cell Death Differ
; 27(8): 2534, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152554
20.
Cervical Gene Delivery of the Antimicrobial Peptide, Human ß-Defensin (HBD)-3, in a Mouse Model of Ascending Infection-Related Preterm Birth.
Front Immunol
; 11: 106, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32117260