Detalhe da pesquisa
1.
Intravitreal injection of a rationally designed AAV capsid library in non-human primate identifies variants with enhanced retinal transduction and neutralizing antibody evasion.
Mol Ther
; 31(12): 3441-3456, 2023 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37814449
2.
Effects of Altering HSPG Binding and Capsid Hydrophilicity on Retinal Transduction by AAV.
J Virol
; 95(10)2021 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33658343
3.
Optimization of Retinal Gene Therapy for X-Linked Retinitis Pigmentosa Due to RPGR Mutations.
Mol Ther
; 25(8): 1866-1880, 2017 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28566226
4.
Preclinical studies in support of phase I/II clinical trials to treat GUCY2D-associated Leber congenital amaurosis.
Mol Ther Methods Clin Dev
; 28: 129-145, 2023 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36654798
5.
A Novel Mouse Model of MYO7A USH1B Reveals Auditory and Visual System Haploinsufficiencies.
Front Neurosci
; 13: 1255, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31824252
6.
Somatic Gene Editing of GUCY2D by AAV-CRISPR/Cas9 Alters Retinal Structure and Function in Mouse and Macaque.
Hum Gene Ther
; 30(5): 571-589, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30358434
7.
Highly Efficient Delivery of Adeno-Associated Viral Vectors to the Primate Retina.
Hum Gene Ther
; 27(8): 580-97, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27439313
8.
Cone-Specific Promoters for Gene Therapy of Achromatopsia and Other Retinal Diseases.
Hum Gene Ther
; 27(1): 72-82, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26603570
9.
A role for cytoskeletal elements in the light-driven translocation of proteins in rod photoreceptors.
Invest Ophthalmol Vis Sci
; 46(11): 3988-98, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16249472
10.
Preclinical evaluation of cathepsin-degradable peptide linkers for radioimmunoconjugates.
Clin Cancer Res
; 9(10 Pt 2): 3865S-72S, 2003 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14506184
11.
Systemic Vascular Transduction by Capsid Mutant Adeno-Associated Virus After Intravenous Injection.
Hum Gene Ther
; 26(11): 767-76, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26359319
12.
Capsid Mutated Adeno-Associated Virus Delivered to the Anterior Chamber Results in Efficient Transduction of Trabecular Meshwork in Mouse and Rat.
PLoS One
; 10(6): e0128759, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26052939
13.
Gene Therapy Fully Restores Vision to the All-Cone Nrl(-/-) Gucy2e(-/-) Mouse Model of Leber Congenital Amaurosis-1.
Hum Gene Ther
; 26(9): 575-92, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26247368
14.
Probing alpha-crystallin structure using chemical cross-linkers and mass spectrometry.
Mol Vis
; 10: 857-66, 2004 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-15570221
15.
The surface of visual arrestin that binds to rhodopsin.
Mol Vis
; 10: 392-8, 2004 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15215746
16.
Arrestin translocation in rod photoreceptors.
Adv Exp Med Biol
; 572: 455-64, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-17249609
17.
Optimizing cellulase usage for improved mixing and rheological properties of acid-pretreated sugarcane bagasse.
Bioresour Technol
; 101(23): 9128-36, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20678927
18.
Arrestin migrates in photoreceptors in response to light: a study of arrestin localization using an arrestin-GFP fusion protein in transgenic frogs.
Exp Eye Res
; 76(5): 553-63, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12697419