Detalhe da pesquisa
1.
Engineering Therapeutics to Detoxify Hemoglobin, Heme, and Iron.
Annu Rev Biomed Eng
; 25: 1-21, 2023 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37289555
2.
Controlled Lipid Self-Assembly for Scalable Manufacturing of Next-Generation Immune Stimulating Complexes.
Chem Eng J
; 4642023 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38737525
3.
Purification and analysis of a protein cocktail capable of scavenging cell-free hemoglobin, heme, and iron.
Transfusion
; 61(6): 1894-1907, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33817808
4.
Apohemoglobin-haptoglobin complex attenuates the pathobiology of circulating acellular hemoglobin and heme.
Am J Physiol Heart Circ Physiol
; 318(5): H1296-H1307, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32302494
5.
Controlled Polymerization and Ultrafiltration Increase the Consistency of Polymerized Hemoglobin for Use as an Oxygen Carrier.
Bioconjug Chem
; 31(3): 605-621, 2020 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31868349
6.
Comprehensive characterization of tense and relaxed quaternary state glutaraldehyde polymerized bovine hemoglobin as a function of cross-link density.
Biotechnol Bioeng
; 117(8): 2362-2376, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32472694
7.
Novel manufacturing method for producing apohemoglobin and its biophysical properties.
Biotechnol Bioeng
; 117(1): 125-145, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31612988
8.
Poly(ethylene glycol) Surface-Conjugated Apohemoglobin as a Synthetic Heme Scavenger.
Biomacromolecules
; 21(6): 2155-2164, 2020 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32186855
9.
Anti-inflammatory effects of haptoglobin on LPS-stimulated macrophages: Role of HMGB1 signaling and implications in chronic wound healing.
Wound Repair Regen
; 28(4): 493-505, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32428978
10.
Quantification of Active Apohemoglobin Heme-Binding Sites via Dicyanohemin Incorporation.
Biochemistry
; 56(40): 5245-5259, 2017 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28846391
11.
Toxic side-effects of diaspirin cross-linked human hemoglobin are attenuated by the apohemoglobin-haptoglobin complex.
Biomed Pharmacother
; 174: 116569, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38603886
12.
STING Protein-Based In Situ Vaccine Synergizes CD4+ T, CD8+ T, and NK Cells for Tumor Eradication.
Adv Healthc Mater
; 12(24): e2300688, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37015729
13.
Human STING is a proton channel.
Science
; 381(6657): 508-514, 2023 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37535724
14.
Synergistic combination therapy delivered via layer-by-layer nanoparticles induces solid tumor regression of ovarian cancer.
Bioeng Transl Med
; 8(2): e10429, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36925689
15.
Layer-by-layer interleukin-12 nanoparticles drive a safe and effective response in ovarian tumors.
Bioeng Transl Med
; 8(2): e10453, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36925719
16.
Apohemoglobin-haptoglobin complex alleviates iron toxicity in mice with ß-thalassemia via scavenging of cell-free hemoglobin and heme.
Biomed Pharmacother
; 156: 113911, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36308920
17.
Engineering Strategies for Immunomodulatory Cytokine Therapies - Challenges and Clinical Progress.
Adv Ther (Weinh)
; 4(8)2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34734110
18.
Tangential flow filtration of haptoglobin.
Biotechnol Prog
; 36(5): e3010, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32348635
19.
Enhanced Photodynamic Therapy Using the Apohemoglobin-Haptoglobin Complex as a Carrier of Aluminum Phthalocyanine.
ACS Appl Bio Mater
; 3(7): 4495-4506, 2020 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35025448
20.
Apohemoglobin-haptoglobin complexes attenuate the hypertensive response to low-molecular-weight polymerized hemoglobin.
Blood Adv
; 4(12): 2739-2750, 2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32559292