Detalhe da pesquisa
1.
Chimeric antigen receptors combining 4-1BB and CD28 signaling domains augment PI3kinase/AKT/Bcl-XL activation and CD8+ T cell-mediated tumor eradication.
Mol Ther
; 18(2): 413-20, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19773745
2.
Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells.
Cancer Res
; 65(23): 11061-70, 2005 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16322256
3.
An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity.
Mol Ther Oncolytics
; 3: 1-9, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-29675462
4.
Tumor-Targeted Human T Cells Expressing CD28-Based Chimeric Antigen Receptors Circumvent CTLA-4 Inhibition.
PLoS One
; 10(6): e0130518, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26110267
5.
Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells.
Cancer Cell
; 28(4): 415-428, 2015 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26461090
6.
Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity.
Sci Transl Med
; 6(261): 261ra151, 2014 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25378643
7.
Critical role for CXCR4 signaling in progenitor localization and T cell differentiation in the postnatal thymus.
J Immunol
; 171(9): 4521-7, 2003 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14568925
8.
Analysis of transcription factor expression during discrete stages of postnatal thymocyte differentiation.
J Immunol
; 173(2): 1094-102, 2004 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15240698