Detalhe da pesquisa
1.
Kynurenine 3-monooxygenase limits de novo NAD+ synthesis through dietary tryptophan in renal proximal tubule epithelial cell models.
Am J Physiol Cell Physiol
; 326(5): C1423-C1436, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38497113
2.
GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets.
Mol Pharmacol
; 93(6): 581-591, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29572336
3.
Discovery of novel benzo[b]thiophene tetrazoles as non-carboxylate GPR40 agonists.
Bioorg Med Chem Lett
; 28(3): 429-436, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29258772
4.
Discovery of a novel potent GPR40 full agonist.
Bioorg Med Chem Lett
; 28(4): 720-726, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29366647
5.
Metabolic tracing of monoacylglycerol acyltransferase-2 activity in vitro and in vivo.
Anal Biochem
; 524: 68-75, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27665677
6.
Acute hemodynamic and renal effects of glucagon-like peptide 1 analog and dipeptidyl peptidase-4 inhibitor in rats.
Cardiovasc Diabetol
; 14: 29, 2015 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25888997
7.
Development of a neuromedin U-human serum albumin conjugate as a long-acting candidate for the treatment of obesity and diabetes. Comparison with the PEGylated peptide.
J Pept Sci
; 20(1): 7-19, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24222478
8.
Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins.
Nat Med
; 13(2): 171-80, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17273170
9.
A PEGylated analog of the gut hormone oxyntomodulin with long-lasting antihyperglycemic, insulinotropic and anorexigenic activity.
Bioorg Med Chem
; 21(22): 7064-73, 2013 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24094437
10.
G protein-coupled receptors and obesity.
Front Endocrinol (Lausanne)
; 14: 1301017, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38161982
11.
Metabolism-based approaches for autosomal dominant polycystic kidney disease.
Front Mol Biosci
; 10: 1126055, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36876046
12.
Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver.
Cell Metab
; 6(3): 208-16, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17767907
13.
Differential effects of oxyntomodulin and GLP-1 on glucose metabolism.
Am J Physiol Endocrinol Metab
; 303(2): E265-71, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22621866
14.
PEGylation of Neuromedin U yields a promising candidate for the treatment of obesity and diabetes.
Bioorg Med Chem
; 20(15): 4751-9, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22771182
15.
Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis.
Nat Med
; 11(3): 320-7, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15735652
16.
A FFAR1 full agonist restores islet function in models of impaired glucose-stimulated insulin secretion and diabetic non-human primates.
Front Endocrinol (Lausanne)
; 13: 1061688, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36482991
17.
The mitochondrial fission protein Drp1 in liver is required to mitigate NASH and prevents the activation of the mitochondrial ISR.
Mol Metab
; 64: 101566, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35940556
18.
Critical role of STAT3 in leptin's metabolic actions.
Cell Metab
; 4(1): 49-60, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16814732
19.
Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats.
J Clin Invest
; 118(8): 2959-68, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18618016
20.
DPP-IV-resistant, long-acting oxyntomodulin derivatives.
J Pept Sci
; 17(4): 270-80, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21294225