Detalhe da pesquisa
1.
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.
Cell
; 153(3): 707-20, 2013 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23622250
2.
A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies.
Toxicol Sci
; 188(1): 4-16, 2022 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35404422
3.
Understanding the effect of increased cell specific productivity on galactosylation of monoclonal antibodies produced using Chinese hamster ovary cells.
J Biotechnol
; 329: 92-103, 2021 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33549674
4.
Quantitative Transcriptional Biomarkers of Xenobiotic Receptor Activation in Rat Liver for the Early Assessment of Drug Safety Liabilities.
Toxicol Sci
; 175(1): 98-112, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32119089
5.
Development and Application of a Transcriptomic Signature of Bioactivation in an Advanced In Vitro Liver Model to Reduce Drug-induced Liver Injury Risk Early in the Pharmaceutical Pipeline.
Toxicol Sci
; 177(1): 121-139, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32559289
6.
Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development That Informs Chemically Reactive Metabolite Formation and Potential for Drug-induced Liver Injury.
Toxicol Sci
; 177(1): 281-299, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32559301
7.
Reconstruction and stability of secondary structure elements in the context of protein structure prediction.
Biophys J
; 96(11): 4399-408, 2009 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19486664
8.
Comparative transcriptomics of choroid plexus in Alzheimer's disease, frontotemporal dementia and Huntington's disease: implications for CSF homeostasis.
Fluids Barriers CNS
; 15(1): 18, 2018 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29848382
9.
Learning about protein hydrogen bonding by minimizing contrastive divergence.
Proteins
; 66(3): 588-99, 2007 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17109405
10.
Transcriptional Profiling of Cholinergic Neurons From Basal Forebrain Identifies Changes in Expression of Genes Between Sleep and Wake.
Sleep
; 40(6)2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28419375
11.
Discovering Biology in Periodic Data through Phase Set Enrichment Analysis (PSEA).
J Biol Rhythms
; 31(3): 244-57, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26955841
12.
Effects of Long-Term Odanacatib Treatment on Bone Gene Expression in Ovariectomized Adult Rhesus Monkeys: Differentiation From Alendronate.
J Bone Miner Res
; 31(4): 839-51, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26587671
13.
Exhaustive Metropolis Monte Carlo sampling and analysis of polyalanine conformations adopted under the influence of hydrogen bonds.
Proteins
; 61(1): 94-104, 2005 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16049911
14.
Blood-gene expression reveals reduced circadian rhythmicity in individuals resistant to sleep deprivation.
Sleep
; 37(10): 1589-600, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25197809
15.
Comment on "Efficient Monte Carlo trial moves for polypeptide simulations" [J. Chem. Phys. 123, 174905 (2005)].
J Chem Phys
; 129(2): 027103, 2008 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-18624565
16.
Transcriptional architecture of the primate neocortex.
Neuron
; 73(6): 1083-99, 2012 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22445337
17.
Toxicogenomics in drug development: a match made in heaven?
Expert Opin Drug Metab Toxicol
; 12(8): 847-9, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27050123
18.
Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging.
PLoS One
; 6(12): e29610, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22216330
19.
CRANKITE: A fast polypeptide backbone conformation sampler.
Source Code Biol Med
; 3: 12, 2008 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-18577227
20.
Modeling HIV-1 integrase complexes based on their hydrodynamic properties.
Biopolymers
; 68(1): 110-20, 2003 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-12579583