Detalhe da pesquisa
1.
A membrane vesicle-based assay to enable prediction of human biliary excretion.
Xenobiotica
; 43(10): 915-9, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23402371
2.
Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ.
J Med Chem
; 65(19): 13198-13215, 2022 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36126059
3.
Biarylimidazoles as inhibitors of microsomal prostaglandin E2 synthase-1.
Bioorg Med Chem Lett
; 20(23): 6978-82, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20965723
4.
MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis.
J Pharmacol Exp Ther
; 325(2): 425-34, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18287210
5.
Bisphosphonated fluoroquinolone esters as osteotropic prodrugs for the prevention of osteomyelitis.
Bioorg Med Chem
; 16(20): 9217-29, 2008 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18815051
6.
A strategy to reduce biliary clearance in early drug discovery.
J Pharmacol Toxicol Methods
; 68(3): 346-8, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23518065
7.
Mercury and flooding cycles in the Tapajós River basin, Brazilian Amazon: the role of periphyton of a floating macrophyte (Paspalum repens).
Sci Total Environ
; 409(14): 2746-53, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21536317
8.
Linking bisphosphonates to the free amino groups in fluoroquinolones: preparation of osteotropic prodrugs for the prevention of osteomyelitis.
J Med Chem
; 51(21): 6955-69, 2008 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18834106
9.
Novel non-nucleobase inhibitors of Staphylococcus aureus DNA polymerase IIIC.
Bioorg Med Chem Lett
; 16(4): 891-6, 2006 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16298129
10.
Allotopic antagonism of the non-peptide atrial natriuretic peptide (ANP) antagonist HS-142-1 on natriuretic peptide receptor NPR-A.
Biochem J
; 362(Pt 1): 231-7, 2002 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-11829760