Detalhe da pesquisa
1.
In vivo CRISPR editing with no detectable genome-wide off-target mutations.
Nature
; 561(7723): 416-419, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30209390
2.
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model.
BMC Biol
; 17(1): 4, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30646909
3.
PA28αß overexpression enhances learning and memory of female mice without inducing 20S proteasome activity.
BMC Neurosci
; 19(1): 70, 2018 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30400847
4.
Long-term stimulation of neural progenitor cell migration after cortical ischemia in mice.
Stroke
; 42(12): 3559-65, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21980195
5.
Changes in the solubility and phosphorylation of α-synuclein over the course of Parkinson's disease.
Acta Neuropathol
; 121(6): 695-704, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21400129
6.
Universal toxin-based selection for precise genome engineering in human cells.
Nat Commun
; 12(1): 497, 2021 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33479216
7.
Can animal models of disease reliably inform human studies?
PLoS Med
; 7(3): e1000245, 2010 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20361020
8.
Cranial irradiation at early postnatal age impairs stroke-induced neural stem/progenitor cell response in the adult brain.
Sci Rep
; 10(1): 12369, 2020 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32703986
9.
Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery.
Nat Commun
; 11(1): 4903, 2020 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32994412
10.
Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq.
Science
; 364(6437): 286-289, 2019 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31000663
11.
IDOL regulates systemic energy balance through control of neuronal VLDLR expression.
Nat Metab
; 1(11): 1089-1100, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32072135
12.
Comparison of inflammation in the brain and spinal cord following mechanical injury.
J Neurotrauma
; 25(10): 1217-25, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18986223
13.
Stimulation of axonal sprouting by trophic factors immobilized within the wound core.
Brain Res
; 1209: 49-56, 2008 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18396265
14.
Therapeutic Genome Editing With CRISPR/Cas9 in a Humanized Mouse Model Ameliorates α1-antitrypsin Deficiency Phenotype.
EBioMedicine
; 29: 104-111, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29500128
15.
Author Correction: Universal toxin-based selection for precise genome engineering in human cells.
Nat Commun
; 12(1): 2832, 2021 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33972550
16.
Imaging the ischemic penumbra with 18F-fluoromisonidazole in a rat model of ischemic stroke.
Stroke
; 35(4): 975-80, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15017016
17.
Photothrombosis-induced infarction of the mouse cerebral cortex is not affected by the Nrf2-activator sulforaphane.
PLoS One
; 7(7): e41090, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22911746
18.
Trauma-induced reactive gliosis is reduced after treatment with octanol and carbenoxolone.
Neurol Res
; 33(6): 614-24, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21708071
19.
ACE inhibition reduces infarction in normotensive but not hypertensive rats: correlation with cortical ACE activity.
J Cereb Blood Flow Metab
; 30(8): 1520-6, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20407464
20.
Different strokes for different folks: the rich diversity of animal models of focal cerebral ischemia.
J Cereb Blood Flow Metab
; 30(8): 1412-31, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20485296