Detalhe da pesquisa
1.
MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer.
Breast Cancer Res
; 22(1): 87, 2020 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32787886
2.
Protein diversity in discrete structures at the distal tip of the trypanosome flagellum.
Proc Natl Acad Sci U S A
; 114(32): E6546-E6555, 2017 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28724725
3.
Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.
Breast Cancer Res
; 21(1): 43, 2019 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30898150
4.
A Role for Chlorinated Nucleosides in the Perturbation of Macrophage Function and Promotion of Inflammation.
Chem Res Toxicol
; 32(6): 1223-1234, 2019 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31066272
5.
Evidence of intraflagellar transport and apical complex formation in a free-living relative of the apicomplexa.
Eukaryot Cell
; 13(1): 10-20, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24058169
6.
The potential of epigenetic therapy to target the 3D epigenome in endocrine-resistant breast cancer.
Nat Struct Mol Biol
; 31(3): 498-512, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38182927
7.
Proteomics and the Trypanosoma brucei cytoskeleton: advances and opportunities.
Parasitology
; 139(9): 1168-77, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22475638
8.
Flagellar motility is required for the viability of the bloodstream trypanosome.
Nature
; 440(7081): 224-7, 2006 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-16525475
9.
Epigenetic Therapies and Biomarkers in Breast Cancer.
Cancers (Basel)
; 14(3)2022 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35158742
10.
MDM2 as a Rational Target for Intervention in CDK4/6 Inhibitor Resistant, Hormone Receptor Positive Breast Cancer.
Front Oncol
; 11: 777867, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34804982
11.
Molecular Biomarkers for Contemporary Therapies in Hormone Receptor-Positive Breast Cancer.
Genes (Basel)
; 12(2)2021 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33671468
12.
Co-targeting CDK4/6 and AKT with endocrine therapy prevents progression in CDK4/6 inhibitor and endocrine therapy-resistant breast cancer.
Nat Commun
; 12(1): 5112, 2021 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34433817
13.
Synergistic targeting of BRCA1 mutated breast cancers with PARP and CDK2 inhibition.
NPJ Breast Cancer
; 7(1): 111, 2021 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34465787
14.
DNA methylation is required to maintain both DNA replication timing precision and 3D genome organization integrity.
Cell Rep
; 36(12): 109722, 2021 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34551299
15.
Targeting CDK2 in cancer: challenges and opportunities for therapy.
Drug Discov Today
; 25(2): 406-413, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31839441
16.
Analysis of the trypanosome flagellar proteome using a combined electron transfer/collisionally activated dissociation strategy.
J Am Soc Mass Spectrom
; 20(2): 167-75, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18930411
17.
Overcoming CDK4/6 inhibitor resistance in ER-positive breast cancer.
Endocr Relat Cancer
; 26(1): R15-R30, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30389903
18.
Non-canonical AR activity facilitates endocrine resistance in breast cancer.
Endocr Relat Cancer
; 26(2): 251-264, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30557851
19.
Triple combination targeting PI3K, ER, and CDK4/6 inhibits growth of ER-positive breast cancer resistant to fulvestrant and CDK4/6 or PI3K inhibitor.
Cancer Commun (Lond)
; 43(6): 720-725, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37101393
20.
A new sophistication for breast cancer PDXs.
Nat Cancer
; 3(2): 138-140, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35221337