Detalhe da pesquisa
1.
Selective Replacement of Cholesterol with Cationic Amphiphilic Drugs Enables the Design of Lipid Nanoparticles with Improved RNA Delivery.
Nano Lett
; 24(10): 2961-2971, 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38477058
2.
Off-target activity of NBOMes and NBOMe analogs at the µ opioid receptor.
Arch Toxicol
; 97(5): 1367-1384, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36853332
3.
In vitro assays for the functional characterization of (psychedelic) substances at the serotonin receptor 5-HT2A R.
J Neurochem
; 162(1): 39-59, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34978711
4.
The P2Y2 Receptor C-Terminal Tail Modulates but Is Dispensable for ß-Arrestin Recruitment.
Int J Mol Sci
; 23(7)2022 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35408820
5.
Enlightening the "Spirit Molecule": Photomodulation of the 5-HT2A Receptor by a Light-Controllable N,N-Dimethyltryptamine Derivative.
Angew Chem Int Ed Engl
; 61(26): e202203034, 2022 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35349196
6.
In vitro structure-activity relationship determination of 30 psychedelic new psychoactive substances by means of ß-arrestin 2 recruitment to the serotonin 2A receptor.
Arch Toxicol
; 94(10): 3449-3460, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32627074
7.
Correction to: In vitro structure-activity relationship determination of 30 psychedelic new psychoactive substances by means of ß-arrestin 2 recruitment to the serotonin 2A receptor.
Arch Toxicol
; 94(10): 3461, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32789674
8.
Setup of a Serotonin 2A Receptor (5-HT2AR) Bioassay: Demonstration of Its Applicability To Functionally Characterize Hallucinogenic New Psychoactive Substances and an Explanation Why 5-HT2AR Bioassays Are Not Suited for Universal Activity-Based Screening of Biofluids for New Psychoactive Substances.
Anal Chem
; 91(24): 15444-15452, 2019 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31725281
9.
Comparative Pharmacological Effects of Lisuride and Lysergic Acid Diethylamide Revisited.
ACS Pharmacol Transl Sci
; 7(3): 641-653, 2024 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38481684
10.
Assay-Dependent Inverse Agonism at the A3 Adenosine Receptor: When Neutral Is Not Neutral.
ACS Pharmacol Transl Sci
; 6(9): 1266-1274, 2023 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37705594
11.
Structure-Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT2A Receptor Agonists.
ACS Chem Neurosci
; 14(15): 2727-2742, 2023 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37474114
12.
In Vitro and In Vivo Evaluation of Pellotine: A Hypnotic Lophophora Alkaloid.
ACS Pharmacol Transl Sci
; 6(10): 1492-1507, 2023 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37854625
13.
A3 adenosine receptor agonists containing dopamine moieties for enhanced interspecies affinity.
Eur J Med Chem
; 228: 113983, 2022 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34844790
14.
Discovery of ß-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists.
J Med Chem
; 65(18): 12031-12043, 2022 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36099411
15.
Structure-Activity Relationships for Psilocybin, Baeocystin, Aeruginascin, and Related Analogues to Produce Pharmacological Effects in Mice.
ACS Pharmacol Transl Sci
; 5(11): 1181-1196, 2022 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36407948
16.
A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs.
J Control Release
; 350: 256-270, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35963467
17.
Synthesis and Functional Characterization of 2-(2,5-Dimethoxyphenyl)-N-(2-fluorobenzyl)ethanamine (25H-NBF) Positional Isomers.
ACS Chem Neurosci
; 12(9): 1667-1673, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33906351
18.
Serotonin 2A Receptor (5-HT2AR) Activation by 25H-NBOMe Positional Isomers: In Vitro Functional Evaluation and Molecular Docking.
ACS Pharmacol Transl Sci
; 4(2): 479-487, 2021 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33860178
19.
Identification of psychedelic new psychoactive substances (NPS) showing biased agonism at the 5-HT2AR through simultaneous use of ß-arrestin 2 and miniGαq bioassays.
Biochem Pharmacol
; 182: 114251, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32998000
20.
Assessment of biased agonism at the A3 adenosine receptor using ß-arrestin and miniGαi recruitment assays.
Biochem Pharmacol
; 177: 113934, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32224136