Detalhe da pesquisa
1.
PH domain leucine-rich repeat protein phosphatase 2 (PHLPP2) regulates G-protein-coupled receptor kinase 5 (GRK5)-induced cardiac hypertrophy in vitro.
J Biol Chem
; 293(21): 8056-8064, 2018 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29628444
2.
APJ acts as a dual receptor in cardiac hypertrophy.
Nature
; 488(7411): 394-8, 2012 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22810587
3.
Selective coupling of the S1P3 receptor subtype to S1P-mediated RhoA activation and cardioprotection.
J Mol Cell Cardiol
; 103: 1-10, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28017639
4.
Decline in cellular function of aged mouse c-kit+ cardiac progenitor cells.
J Physiol
; 595(19): 6249-6262, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28737214
5.
Sphingosine 1-phosphate receptor 3 and RhoA signaling mediate inflammatory gene expression in astrocytes.
J Neuroinflammation
; 14(1): 111, 2017 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28577576
6.
Phospholipase C epsilon links G protein-coupled receptor activation to inflammatory astrocytic responses.
Proc Natl Acad Sci U S A
; 110(9): 3609-14, 2013 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23401561
7.
Ca2+/Calmodulin-dependent protein kinase II δ mediates myocardial ischemia/reperfusion injury through nuclear factor-κB.
Circ Res
; 112(6): 935-44, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23388157
8.
Collagen XIV is important for growth and structural integrity of the myocardium.
J Mol Cell Cardiol
; 53(5): 626-38, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22906538
9.
PHLPP-1 negatively regulates Akt activity and survival in the heart.
Circ Res
; 107(4): 476-84, 2010 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20576936
10.
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death.
Nature
; 434(7033): 658-62, 2005 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-15800627
11.
On the PHLPPside: Emerging roles of PHLPP phosphatases in the heart.
Cell Signal
; 86: 110097, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34320369
12.
Activation of nuclear factor-kappaB is necessary for myotrophin-induced cardiac hypertrophy.
J Cell Biol
; 159(6): 1019-28, 2002 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-12486112
13.
Extracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytes.
Mol Cell Biol
; 24(3): 1081-95, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-14729955
14.
mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2.
Nat Commun
; 7: 10255, 2016 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26743335
15.
Sphingosine 1-phosphate elicits RhoA-dependent proliferation and MRTF-A mediated gene induction in CPCs.
Cell Signal
; 28(8): 871-9, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27094722
16.
MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo.
Circulation
; 109(16): 1938-41, 2004 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-15096454
17.
Physiological activation of Akt by PHLPP1 deletion protects against pathological hypertrophy.
Cardiovasc Res
; 105(2): 160-70, 2015 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25411382
18.
PHLPP1 gene deletion protects the brain from ischemic injury.
J Cereb Blood Flow Metab
; 33(2): 196-204, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23072745
19.
RhoA protects the mouse heart against ischemia/reperfusion injury.
J Clin Invest
; 121(8): 3269-76, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21747165
20.
Is nuclear factor kappaB an attractive therapeutic target for treating cardiac hypertrophy?
Circulation
; 108(6): 638-40, 2003 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-12912791