Detalhe da pesquisa
1.
Difficult-to-express antigen generation through a co-expression and disassociation methodology.
Biotechnol Prog
; 40(2): e3416, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38093578
2.
LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants.
Cell Rep
; 39(7): 110812, 2022 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35568025
3.
LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants.
bioRxiv
; 2022 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33972947
4.
Target modulation and pharmacokinetics/pharmacodynamics translation of the BTK inhibitor poseltinib for model-informed phase II dose selection.
Sci Rep
; 11(1): 18671, 2021 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34548595
5.
The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates.
Sci Transl Med
; 13(593)2021 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33820835
6.
Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
PLoS One
; 15(9): e0232311, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32915778
7.
LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection.
bioRxiv
; 2020 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33024963
8.
Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the RB1 Tumor Suppressor Gene.
Cancer Discov
; 9(2): 248-263, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30373917
9.
Computationally Designed Bispecific Antibodies using Negative State Repertoires.
Structure
; 24(4): 641-651, 2016 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26996964
10.
Indole Glucocorticoid Receptor Antagonists Active in a Model of Dyslipidemia Act via a Unique Association with an Agonist Binding Site.
J Med Chem
; 58(16): 6607-18, 2015 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26218343
11.
Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat Biotechnol
; 32(2): 191-8, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24463572
12.
Glucocorticoid receptor modulators informed by crystallography lead to a new rationale for receptor selectivity, function, and implications for structure-based design.
J Med Chem
; 57(3): 849-60, 2014 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24446728