Detalhe da pesquisa
1.
Small molecule activators of TAK1 promotes its activity-dependent ubiquitination and TRAIL-mediated tumor cell death.
Proc Natl Acad Sci U S A
; 120(39): e2308079120, 2023 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37733743
2.
Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis.
Proc Natl Acad Sci U S A
; 115(9): E2001-E2009, 2018 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29440439
3.
Activation and function of receptor tyrosine kinases in human clear cell renal cell carcinomas.
BMC Cancer
; 19(1): 1044, 2019 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31690270
4.
2-Methoxystypandrone inhibits signal transducer and activator of transcription 3 and nuclear factor-κB signaling by inhibiting Janus kinase 2 and IκB kinase.
Cancer Sci
; 105(4): 473-80, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24450414
5.
Structure-based development of potent and selective type-II kinase inhibitors of RIPK1.
Acta Pharm Sin B
; 14(1): 319-334, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38261830
6.
Therapeutic targeting of CPSF3-dependent transcriptional termination in ovarian cancer.
Sci Adv
; 9(47): eadj0123, 2023 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37992178
7.
Discovery of Potent OTUB1/USP8 Dual Inhibitors Targeting Proteostasis in Non-Small-Cell Lung Cancer.
J Med Chem
; 65(20): 13645-13659, 2022 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36221183
8.
SOX17 and PAX8 constitute an actionable lineage-survival transcriptional complex in ovarian cancer.
Oncogene
; 41(12): 1767-1779, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35124696
9.
SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation.
Cell Res
; 31(12): 1230-1243, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34663909
10.
Age-related differential sensitivity to MK-801-induced locomotion and stereotypy in C57BL/6 mice.
Eur J Pharmacol
; 580(1-2): 161-8, 2008 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18053981
11.
Activation of necroptosis in multiple sclerosis.
Cell Rep
; 10(11): 1836-49, 2015 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25801023
12.
G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L.
Elife
; 4: e06734, 2015 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25821988
13.
Inhibitory activities of Lignum Sappan extractives on growth and growth-related signaling of tumor cells.
Chin J Nat Med
; 12(8): 607-12, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25156286
14.
Arctigenin preferentially induces tumor cell death under glucose deprivation by inhibiting cellular energy metabolism.
Biochem Pharmacol
; 84(4): 468-76, 2012 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22687625
15.
Effect of GNTI, a kappa opioid receptor antagonist, on MK-801-induced hyperlocomotion and stereotypy in mice.
Acta Pharmacol Sin
; 27(11): 1401-8, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17049114