Detalhe da pesquisa
1.
Species-Specific N-Glycomes and Methylation Patterns of Oysters Crassostrea gigas and Ostrea edulis and Their Possible Consequences for the Norovirus-HBGA Interaction.
Mar Drugs
; 21(6)2023 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37367667
2.
Biological, clinical features and modelling of heterozygous variants of glycoprotein Ib platelet subunit alpha (GP1BA) and glycoprotein Ib platelet subunit beta (GP1BB) genes responsible for constitutional thrombocytopenia.
Br J Haematol
; 199(5): 744-753, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36173017
3.
IL-15Rα membrane anchorage in either cis or trans is required for stabilization of IL-15 and optimal signaling.
J Cell Sci
; 133(5)2019 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31653781
4.
Rational modification, synthesis and biological evaluation of N-substituted phthalazinone derivatives designed to target interleukine-15 protein.
Bioorg Med Chem
; 39: 116161, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33932805
5.
Emergence of NK Cell Hyporesponsiveness after Two IL-15 Stimulation Cycles.
J Immunol
; 201(2): 493-506, 2018 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29848756
6.
Cutting Edge: Differential Fine-Tuning of IL-2- and IL-15-Dependent Functions by Targeting Their Common IL-2/15Rß/γc Receptor.
J Immunol
; 198(12): 4563-4568, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28507024
7.
Mechanistic and Structural Insights on the IL-15 System through Molecular Dynamics Simulations.
Molecules
; 24(18)2019 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31500206
8.
Tumor targeting of the IL-15 superagonist RLI by an anti-GD2 antibody strongly enhances its antitumor potency.
Int J Cancer
; 133(3): 757-65, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23354868
9.
Counteracting Interleukin-15 to Elucidate Its Modes of Action in Physiology and Pathology.
J Interferon Cytokine Res
; 43(1): 2-22, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36651845
10.
Selective Targeting of IL-15Rα Is Sufficient to Reduce Inflammation.
Front Immunol
; 13: 886213, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35592318
11.
Centromeric KIR AA Individuals Harbor Particular KIR Alleles Conferring Beneficial NK Cell Features with Implications in Haplo-Identical Hematopoietic Stem Cell Transplantation.
Cancers (Basel)
; 12(12)2020 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33271841
12.
Genetic diversity and evolution of Hare Calicivirus (HaCV), a recently identified lagovirus from Lepus europaeus.
Infect Genet Evol
; 82: 104310, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32243924
13.
Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization.
J Med Chem
; 60(14): 6249-6272, 2017 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28657314
14.
Docking of human interleukin-15 to its specific receptor alpha chain: correlation between molecular modeling and mutagenesis experimental data.
Proteins
; 65(3): 623-36, 2006 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17001647
15.
Molecular evolution and antigenic variation of European brown hare syndrome virus (EBHSV).
Virology
; 468-470: 104-112, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25155199
16.
Highly potent anti-CD20-RLI immunocytokine targeting established human B lymphoma in SCID mouse.
MAbs
; 6(4): 1026-37, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25072059
17.
Antitumor activity of an immunocytokine composed of an anti-GD2 antibody and the IL-15 superagonist RLI.
Oncoimmunology
; 2(11): e26441, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24349876
18.
Evolution of interleukin-15 for higher E. coli expression and solubility.
Protein Eng Des Sel
; 24(3): 283-90, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21109548
19.
High antitumor activity of RLI, an interleukin-15 (IL-15)-IL-15 receptor alpha fusion protein, in metastatic melanoma and colorectal cancer.
Mol Cancer Ther
; 8(9): 2736-45, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19723883
20.
The exon-3-encoded domain of IL-15ralpha contributes to IL-15 high-affinity binding and is crucial for the IL-15 antagonistic effect of soluble IL-15Ralpha.
J Mol Biol
; 382(1): 1-12, 2008 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-18656487