Detalhe da pesquisa
1.
Revealing the mechanism of action of a first-in-class covalent inhibitor of KRASG12C (ON) and other functional properties of oncogenic KRAS by 31P NMR.
J Biol Chem
; 300(2): 105650, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38237681
2.
A Top-Down Proteomic Assay to Evaluate KRAS4B-Compound Engagement.
Anal Chem
; 96(13): 5223-5231, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38498381
3.
KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis.
Proc Natl Acad Sci U S A
; 116(44): 22122-22131, 2019 10 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31611389
4.
Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer.
J Biol Chem
; 295(4): 1105-1119, 2020 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31836666
5.
Label-Free Time-Gated Luminescent Detection Method for the Nucleotides with Varying Phosphate Content.
Sensors (Basel)
; 18(11)2018 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30453509
6.
Measurement of KRAS-GTPase Activity.
Methods Mol Biol
; 2797: 91-102, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38570454
7.
KRAS4b:RAF-1 Homogenous Time-Resolved Fluorescence Resonance Energy Transfer Assay for Drug Discovery.
Methods Mol Biol
; 2797: 159-175, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38570459