Detalhe da pesquisa
1.
Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.
Cell
; 149(5): 1008-22, 2012 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22579044
2.
IgG Fc sialylation is regulated during the germinal center reaction following immunization with different adjuvants.
J Allergy Clin Immunol
; 146(3): 652-666.e11, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32445838
3.
Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.
EMBO J
; 35(8): 831-44, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26903602
4.
Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice.
Gastroenterology
; 156(1): 145-159.e19, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30273559
5.
Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy.
Hum Mol Genet
; 26(20): 3960-3972, 2017 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29016854
6.
Tetraspanin 3: A central endocytic membrane component regulating the expression of ADAM10, presenilin and the amyloid precursor protein.
Biochim Biophys Acta Mol Cell Res
; 1864(1): 217-230, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27818272
7.
IL-6 trans-signaling is essential for the development of hepatocellular carcinoma in mice.
Hepatology
; 65(1): 89-103, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27770462
8.
Circulating Soluble IL-6R but Not ADAM17 Activation Drives Mononuclear Cell Migration in Tissue Inflammation.
J Immunol
; 197(9): 3705-3715, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27698010
9.
Human and Murine Interleukin 23 Receptors Are Novel Substrates for A Disintegrin and Metalloproteases ADAM10 and ADAM17.
J Biol Chem
; 291(20): 10551-61, 2016 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26961870
10.
Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to Circulating Microvesicles.
J Biol Chem
; 290(43): 26059-71, 2015 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26359498
11.
Secreted Frizzled-related protein 3 (sFRP3)-mediated suppression of interleukin-6 receptor release by A disintegrin and metalloprotease 17 (ADAM17) is abrogated in the osteoarthritis-associated rare double variant of sFRP3.
Biochem J
; 468(3): 507-18, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25846075
12.
The amino acid exchange R28E in ciliary neurotrophic factor (CNTF) abrogates interleukin-6 receptor-dependent but retains CNTF receptor-dependent signaling via glycoprotein 130 (gp130)/leukemia inhibitory factor receptor (LIFR).
J Biol Chem
; 289(26): 18442-50, 2014 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24802752
13.
Polo-like kinase 2, a novel ADAM17 signaling component, regulates tumor necrosis factor α ectodomain shedding.
J Biol Chem
; 289(5): 3080-93, 2014 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-24338472
14.
Senescence-associated release of transmembrane proteins involves proteolytic processing by ADAM17 and microvesicle shedding.
FASEB J
; 28(11): 4847-56, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25077560
15.
Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17.
Biochim Biophys Acta
; 1833(12): 3355-3367, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24135057
16.
Unraveling viral interleukin-6 binding to gp130 and activation of STAT-signaling pathways independently of the interleukin-6 receptor.
J Virol
; 83(10): 5117-26, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19264784
17.
Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis.
J Exp Med
; 216(4): 807-830, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30819724
18.
ADAM10 sheddase activation is controlled by cell membrane asymmetry.
J Mol Cell Biol
; 11(11): 979-993, 2019 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30753537
19.
Correction: The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth.
Oncotarget
; 9(73): 33865, 2018 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30333916
20.
RNase H2 Loss in Murine Astrocytes Results in Cellular Defects Reminiscent of Nucleic Acid-Mediated Autoinflammation.
Front Immunol
; 9: 587, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29662492