Detalhe da pesquisa
1.
Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis.
J Hepatol
; 80(2): 268-281, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37939855
2.
Benchmark of filter methods for feature selection in high-dimensional gene expression survival data.
Brief Bioinform
; 23(1)2022 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34498681
3.
In vivo alkaline comet assay: Statistical considerations on historical negative and positive control data.
Regul Toxicol Pharmacol
; 148: 105583, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38401761
4.
Designs for the simultaneous inference of concentration-response curves.
BMC Bioinformatics
; 24(1): 393, 2023 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37858091
5.
Statistical analysis of high-dimensional biomedical data: a gentle introduction to analytical goals, common approaches and challenges.
BMC Med
; 21(1): 182, 2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37189125
6.
Long-term hypercaloric diet exacerbates metabolic liver disease in PNPLA3 I148M animals.
Liver Int
; 43(8): 1699-1713, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37073116
7.
Guidance for statistical design and analysis of toxicological dose-response experiments, based on a comprehensive literature review.
Arch Toxicol
; 97(10): 2741-2761, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37572131
8.
Identification of an FXR-modulated liver-intestine hybrid state in iPSC-derived hepatocyte-like cells.
J Hepatol
; 77(5): 1386-1398, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35863491
9.
Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity.
J Hepatol
; 77(1): 71-83, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35131407
10.
Comparison Of Observation-Based And Model-Based Identification Of Alert Concentrations From Concentration-Expression Data.
Bioinformatics
; 2021 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33515236
11.
Classification of Developmental Toxicants in a Human iPSC Transcriptomics-Based Test.
Chem Res Toxicol
; 35(5): 760-773, 2022 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35416653
12.
Kinetic modeling of stem cell transcriptome dynamics to identify regulatory modules of normal and disturbed neuroectodermal differentiation.
Nucleic Acids Res
; 48(22): 12577-12592, 2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33245762
13.
Model selection characteristics when using MCP-Mod for dose-response gene expression data.
Biom J
; 64(5): 883-897, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35187701
14.
Improving adaptive seamless designs through Bayesian optimization.
Biom J
; 64(5): 948-963, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35212423
15.
Combining heterogeneous subgroups with graph-structured variable selection priors for Cox regression.
BMC Bioinformatics
; 22(1): 586, 2021 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34895139
16.
Weighted Cox regression for the prediction of heterogeneous patient subgroups.
BMC Med Inform Decis Mak
; 21(1): 342, 2021 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34876106
17.
Cost-Constrained feature selection in binary classification: adaptations for greedy forward selection and genetic algorithms.
BMC Bioinformatics
; 21(1): 26, 2020 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31992203
18.
Model-based optimization of subgroup weights for survival analysis.
Bioinformatics
; 35(14): i484-i491, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31510644
19.
Handling deviating control values in concentration-response curves.
Arch Toxicol
; 94(11): 3787-3798, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32965549
20.
Development of a neural rosette formation assay (RoFA) to identify neurodevelopmental toxicants and to characterize their transcriptome disturbances.
Arch Toxicol
; 94(1): 151-171, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31712839