Detalhe da pesquisa
1.
Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide.
Nature
; 619(7971): 811-818, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37407817
2.
Characterization of multi-DAA resistance using a novel hepatitis C virus genotype 3a infectious culture system.
Hepatology
; 78(2): 621-636, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36999539
3.
HCV genome-wide analysis for development of efficient culture systems and unravelling of antiviral resistance in genotype 4.
Gut
; 71(3): 627-642, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33833066
4.
Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 In Vitro.
Antimicrob Agents Chemother
; 65(9): e0268020, 2021 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34097489
5.
Overcoming Culture Restriction for SARS-CoV-2 in Human Cells Facilitates the Screening of Compounds Inhibiting Viral Replication.
Antimicrob Agents Chemother
; 65(7): e0009721, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33903110
6.
Mutations Identified in the Hepatitis C Virus (HCV) Polymerase of Patients with Chronic HCV Treated with Ribavirin Cause Resistance and Affect Viral Replication Fidelity.
Antimicrob Agents Chemother
; 64(12)2020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32928732
7.
Cell Culture Studies of the Efficacy and Barrier to Resistance of Sofosbuvir-Velpatasvir and Glecaprevir-Pibrentasvir against Hepatitis C Virus Genotypes 2a, 2b, and 2c.
Antimicrob Agents Chemother
; 64(3)2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31818814
8.
Insights into the unique characteristics of hepatitis C virus genotype 3 revealed by development of a robust sub-genomic DBN3a replicon.
J Gen Virol
; 101(11): 1182-1190, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32897181
9.
Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants.
Hepatology
; 70(3): 771-787, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30964552
10.
HCV genotype 1-6 NS3 residue 80 substitutions impact protease inhibitor activity and promote viral escape.
J Hepatol
; 70(3): 388-397, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30395912
11.
HCV Genotype 6a Escape From and Resistance to Velpatasvir, Pibrentasvir, and Sofosbuvir in Robust Infectious Cell Culture Models.
Gastroenterology
; 154(8): 2194-2208.e12, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29454794
12.
Efficacy of NS5A Inhibitors Against Hepatitis C Virus Genotypes 1-7 and Escape Variants.
Gastroenterology
; 154(5): 1435-1448, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29274866
13.
Ribavirin-induced mutagenesis across the complete open reading frame of hepatitis C virus genotypes 1a and 3a.
J Gen Virol
; 99(8): 1066-1077, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29927371
14.
Efficient Hepatitis C Virus Genotype 1b Core-NS5A Recombinants Permit Efficacy Testing of Protease and NS5A Inhibitors.
Antimicrob Agents Chemother
; 61(6)2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28348150
15.
Robust HCV Genotype 3a Infectious Cell Culture System Permits Identification of Escape Variants With Resistance to Sofosbuvir.
Gastroenterology
; 151(5): 973-985.e2, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27453546
16.
Hepatitis C Virus Genotype 1 to 6 Protease Inhibitor Escape Variants: In Vitro Selection, Fitness, and Resistance Patterns in the Context of the Infectious Viral Life Cycle.
Antimicrob Agents Chemother
; 60(6): 3563-78, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27021330
17.
Efficient infectious cell culture systems of the hepatitis C virus (HCV) prototype strains HCV-1 and H77.
J Virol
; 89(1): 811-23, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25355880
18.
Substitutions at NS3 Residue 155, 156, or 168 of Hepatitis C Virus Genotypes 2 to 6 Induce Complex Patterns of Protease Inhibitor Resistance.
Antimicrob Agents Chemother
; 59(12): 7426-36, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26392503
19.
Quasispecies dynamics in hepatitis C liver transplant recipients receiving grafts from hepatitis C virus infected donors.
J Gen Virol
; 96(12): 3493-3498, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26395289
20.
Differential sensitivity of 5'UTR-NS5A recombinants of hepatitis C virus genotypes 1-6 to protease and NS5A inhibitors.
Gastroenterology
; 146(3): 812-821.e4, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24262279