Detalhe da pesquisa
1.
Germline variant FGFR4 p.G388R exposes a membrane-proximal STAT3 binding site.
Nature
; 528(7583): 570-4, 2015 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26675719
2.
C-Raf deficiency leads to hearing loss and increased noise susceptibility.
Cell Mol Life Sci
; 72(20): 3983-98, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25975225
3.
Elimination of B-RAF in oncogenic C-RAF-expressing alveolar epithelial type II cells reduces MAPK signal intensity and lung tumor growth.
J Biol Chem
; 289(39): 26804-26816, 2014 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25096573
4.
Disruption of tumor cell adhesion promotes angiogenic switch and progression to micrometastasis in RAF-driven murine lung cancer.
Cancer Cell
; 12(2): 145-59, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17692806
5.
Tyr728 in the kinase domain of the murine kinase suppressor of RAS 1 regulates binding and activation of the mitogen-activated protein kinase kinase.
J Biol Chem
; 288(49): 35237-52, 2013 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24158441
6.
BuCy RAFs drive cells into MEK addiction.
Cancer Cell
; 9(1): 9-12, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16413467
7.
Role of melanoma inhibitor of apoptosis (ML-IAP) protein, a member of the baculoviral IAP repeat (BIR) domain family, in the regulation of C-RAF kinase and cell migration.
J Biol Chem
; 287(34): 28445-55, 2012 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22711539
8.
The tumor suppressor DiRas3 forms a complex with H-Ras and C-RAF proteins and regulates localization, dimerization, and kinase activity of C-RAF.
J Biol Chem
; 287(27): 23128-40, 2012 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22605333
9.
BAD contributes to RAF-mediated proliferation and cooperates with B-RAF-V600E in cancer signaling.
J Biol Chem
; 286(20): 17934-44, 2011 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21317286
10.
Single substitution within the RKTR motif impairs kinase activity but promotes dimerization of RAF kinase.
J Biol Chem
; 286(18): 16491-503, 2011 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21454547
11.
Pore-forming activity of BAD is regulated by specific phosphorylation and structural transitions of the C-terminal part.
Biochim Biophys Acta
; 1810(2): 162-9, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21081150
12.
Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells.
Int J Cancer
; 131(12): 2808-19, 2012 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22511343
13.
Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration.
Nat Cell Biol
; 7(8): 837-43, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16041367
14.
Polycomb group protein Bmi1 negatively regulates IL-10 expression in activated macrophages.
Immunol Cell Biol
; 89(7): 812-6, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21221124
15.
Specific antibody-receptor interactions trigger InlAB-independent uptake of Listeria monocytogenes into tumor cell lines.
BMC Microbiol
; 11: 163, 2011 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21745384
16.
Synergistic anti-tumor efficacy of oncolytic influenza viruses and B7-H3 immune- checkpoint inhibitors against IC-resistant lung cancers.
Oncoimmunology
; 10(1): 1885778, 2021 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33643696
17.
Identification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylation.
J Biol Chem
; 284(41): 28004-28020, 2009 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19667065
18.
Metastasis-Associated Protein 2 Represses NF-κB to Reduce Lung Tumor Growth and Inflammation.
Cancer Res
; 80(19): 4199-4211, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32816854
19.
Improvement of the live vaccine strain Salmonella enterica serovar Typhi Ty21a for antigen delivery via the hemolysin secretion system of Escherichia coli.
Int J Med Microbiol
; 299(2): 109-19, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18706861
20.
Thrombopoietin inhibits nerve growth factor-induced neuronal differentiation and ERK signalling.
Cell Signal
; 20(1): 154-62, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18006272