Detalhe da pesquisa
1.
Amyloid-α Peptide Formed through Alternative Processing of the Amyloid Precursor Protein Attenuates Alzheimer's Amyloid-ß Toxicity via Cross-Chaperoning.
J Am Chem Soc
; 146(4): 2634-2645, 2024 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38236059
2.
Racemic Peptides from Amyloid ß and Amylin Form Rippled ß-Sheets Rather Than Pleated ß-Sheets.
J Am Chem Soc
; 145(47): 25917-25926, 2023 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37972334
3.
Evidence for aggregation-independent, PrPC-mediated Aß cellular internalization.
Proc Natl Acad Sci U S A
; 117(46): 28625-28631, 2020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33139554
4.
An Enantiomeric Fragment Pair (EFP) Approach for the Study of Cellular Uptake of Intrinsically Disordered Proteins.
Chembiochem
; 23(15): e202200146, 2022 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35417609
5.
A Hybrid Structural Method for Investigating Low Molecular Weight Oligomeric Structures of Amyloid Beta.
Chembiochem
; 23(23): e202200333, 2022 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35980391
6.
Defining the Landscape of the Pauling-Corey Rippled Sheet: An Orphaned Motif Finding New Homes.
Acc Chem Res
; 54(10): 2488-2501, 2021 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33901396
7.
A robust preparation method for the amyloidogenic and intrinsically disordered amyloid-α peptide.
J Pept Sci
; 28(10): e3414, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35484922
8.
Constraints on the Structure of Fibrils Formed by a Racemic Mixture of Amyloid-ß Peptides from Solid-State NMR, Electron Microscopy, and Theory.
J Am Chem Soc
; 143(33): 13299-13313, 2021 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34375097
9.
A DFT study of structure and stability of pleated and rippled cross-ß sheets with hydrophobic sidechains.
Biopolymers
; 112(1): e23391, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32737991
10.
Conformational Selection as the Driving Force of Amyloid ß Chiral Inactivation.
Chembiochem
; 21(20): 2945-2949, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32424959
11.
Assessing Reproducibility in Amyloid ß Research: Impact of Aß Sources on Experimental Outcomes.
Chembiochem
; 21(17): 2425-2430, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32249510
12.
A Facile Method for the Separation of Methionine Sulfoxide Diastereomers, Structural Assignment, and DFT Analysis.
Chemistry
; 26(20): 4467-4470, 2020 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31867799
13.
A Focused Chiral Mutant Library of the Amyloid ß 42 Central Electrostatic Cluster as a Tool To Stabilize Aggregation Intermediates.
J Org Chem
; 85(3): 1385-1391, 2020 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31875394
14.
What Is the "Relevant" Amyloid ß42 Concentration?
Chembiochem
; 20(13): 1725-1726, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30835961
15.
A DFT-Assisted Topological Analysis of Four Polymorphic, S-Shaped Aß42 Fibril Structures.
Chembiochem
; 20(13): 1722-1724, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30821034
16.
Chirality Dependence of Amyloidâ ß Cellular Uptake and a New Mechanistic Perspective.
Chembiochem
; 20(8): 1023-1026, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30550626
17.
Relative Rates of Metal-Free Azide-Alkyne Cycloadditions: Tunability over 3 Orders of Magnitude.
J Org Chem
; 84(21): 13615-13623, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31560548
18.
Chiral Inactivation: An Old Phenomenon with a New Twist.
Chemistry
; 23(67): 16920-16923, 2017 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28948661
19.
Using chiral peptide substitutions to probe the structure function relationship of a key residue of Aß42.
Chirality
; 29(1): 5-9, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27933649
20.
Suppression of Oligomer Formation and Formation of Non-Toxic Fibrils upon Addition of Mirror-Image Aß42 to the Natural l-Enantiomer.
Angew Chem Int Ed Engl
; 56(38): 11506-11510, 2017 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28682473