Detalhe da pesquisa
1.
NIR spectroscopy-CNN-enabled chemometrics for multianalyte monitoring in microbial fermentation.
Biotechnol Bioeng
; 121(6): 1803-1819, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38390805
2.
Impact of Excipient Extraction and Buffer Exchange on Recombinant Monoclonal Antibody Stability.
Mol Pharm
; 21(4): 1872-1883, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38422397
3.
Convolutional Neural Networks Guided Raman Spectroscopy as a Process Analytical Technology (PAT) Tool for Monitoring and Simultaneous Prediction of Monoclonal Antibody Charge Variants.
Pharm Res
; 41(3): 463-479, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38366234
4.
Explainable AI for CHO cell culture media optimization and prediction of critical quality attribute.
Appl Microbiol Biotechnol
; 108(1): 308, 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38656382
5.
Deep learning framework for peak detection at the intact level of therapeutic proteins.
J Sep Sci
; 47(11): e2400051, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38819868
6.
An efficient computational protocol for template-based design of peptides that inhibit interactions involving SARS-CoV-2 proteins.
Proteins
; 91(9): 1222-1234, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37283297
7.
Profiling Enzyme Activity of l-Asparaginase II by NMR-Based Methyl Fingerprinting at Natural Abundance.
J Am Chem Soc
; 145(19): 10826-10838, 2023 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37154467
8.
Rapid Estimation of Size-Based Heterogeneity in Monoclonal Antibodies by Machine Learning-Enhanced Dynamic Light Scattering.
Anal Chem
; 95(21): 8299-8309, 2023 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37200383
9.
High-throughput capillary electrophoresis analysis of biopharmaceuticals utilizing sequential injections.
Electrophoresis
; 44(9-10): 767-774, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36719057
10.
Continuous integrated manufacturing for biopharmaceuticals: A new paradigm or an empty promise?
Biotechnol Bioeng
; 120(2): 333-351, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36111450
11.
Advances in bioreactor control for production of biotherapeutic products.
Biotechnol Bioeng
; 120(5): 1189-1214, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36760086
12.
Digital twin of a continuous chromatography process for mAb purification: Design and model-based control.
Biotechnol Bioeng
; 120(3): 748-766, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36517960
13.
Combined Presence of Ferrous Ions and Hydrogen Peroxide in Normal Saline and In Vitro Models Induces Enhanced Aggregation of Therapeutic IgG due to Hydroxyl Radicals.
Mol Pharm
; 20(6): 3033-3048, 2023 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37189260
14.
Rapid analysis of titer, aggregate, and intact mass of antibody therapeutics using automated multi-dimensional liquid chromatography coupled with native mass spectroscopy.
J Sep Sci
; 46(13): e2201050, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37051663
15.
Long term culturing of CHO cells: phenotypic drift and quality attributes of the expressed monoclonal antibody.
Biotechnol Lett
; 45(3): 357-370, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36707452
16.
A Domain-Shift Invariant CNN Framework for Cardiac MRI Segmentation Across Unseen Domains.
J Digit Imaging
; 36(5): 2148-2163, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37430062
17.
Production of bioactive recombinant monoclonal antibody fragment in periplasm of Escherichia coli expression system.
Prep Biochem Biotechnol
; 53(10): 1288-1296, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37040146
18.
Multiattribute Monitoring of Charge-Based Heterogeneity of Recombinant Monoclonal Antibodies Using 2D HIC-WCX-MS.
Anal Chem
; 94(43): 15018-15026, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36260865
19.
Applications of capillary electrophoresis for biopharmaceutical product characterization.
Electrophoresis
; 43(1-2): 143-166, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34591322
20.
Cole-Cole modeling of real-time capacitance data for estimation of cell physiological properties in recombinant Escherichia coli cultivation.
Biotechnol Bioeng
; 119(3): 922-935, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34964125