Detalhe da pesquisa
1.
Radiogenomics of C9orf72 Expansion Carriers Reveals Global Transposable Element Derepression and Enables Prediction of Thalamic Atrophy and Clinical Impairment.
J Neurosci
; 43(2): 333-345, 2023 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36446586
2.
CK1δ/ε kinases regulate TDP-43 phosphorylation and are therapeutic targets for ALS-related TDP-43 hyperphosphorylation.
Neurobiol Dis
; 196: 106516, 2024 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38677657
3.
Misfolded alpha-synuclein in amyotrophic lateral sclerosis: Implications for diagnosis and treatment.
Eur J Neurol
; 31(4): e16206, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38270442
4.
Phase 1-2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS.
N Engl J Med
; 383(2): 109-119, 2020 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32640130
5.
Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis.
Acta Neuropathol
; 144(3): 413-435, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35778567
6.
Nuclear depletion of RNA-binding protein ELAVL3 (HuC) in sporadic and familial amyotrophic lateral sclerosis.
Acta Neuropathol
; 142(6): 985-1001, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34618203
7.
Elongator subunit 3 (ELP3) modifies ALS through tRNA modification.
Hum Mol Genet
; 27(7): 1276-1289, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29415125
8.
Primary lateral sclerosis: consensus diagnostic criteria.
J Neurol Neurosurg Psychiatry
; 91(4): 373-377, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32029539
9.
Predicting disease specific spinal motor neurons and glia in sporadic ALS.
Neurobiol Dis
; 130: 104523, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31276795
10.
Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS.
EMBO J
; 34(21): 2633-51, 2015 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26330466
11.
Reply: The lower motor neuron homunculus: function matters.
Brain
; 146(6): e36-e38, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36729779
12.
Targeted axonal import (TAxI) peptide delivers functional proteins into spinal cord motor neurons after peripheral administration.
Proc Natl Acad Sci U S A
; 113(9): 2514-9, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26888285
13.
Astrocyte-derived Jagged-1 mitigates deleterious Notch signaling in amyotrophic lateral sclerosis.
Neurobiol Dis
; 119: 26-40, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30010003
14.
Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral sclerosis.
Acta Neuropathol
; 135(3): 459-474, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29196813
15.
Transcriptome-pathology correlation identifies interplay between TDP-43 and the expression of its kinase CK1E in sporadic ALS.
Acta Neuropathol
; 136(3): 405-423, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29881994
16.
Mexiletine for muscle cramps in amyotrophic lateral sclerosis: A randomized, double-blind crossover trial.
Muscle Nerve
; 2018 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29510461
17.
The lower motor neuron homunculus.
Brain
; 145(11): 3727-3729, 2022 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36029046
18.
TDP-43 protein variants as biomarkers in amyotrophic lateral sclerosis.
BMC Neurosci
; 18(1): 20, 2017 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28122516
19.
Pathological TDP-43 changes in Betz cells differ from those in bulbar and spinal α-motoneurons in sporadic amyotrophic lateral sclerosis.
Acta Neuropathol
; 133(1): 79-90, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27757524
20.
Misfolded SOD1 is not a primary component of sporadic ALS.
Acta Neuropathol
; 134(1): 97-111, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28247063