Detalhe da pesquisa
1.
Stable IgG-like bispecific antibodies directed toward the type I insulin-like growth factor receptor demonstrate enhanced ligand blockade and anti-tumor activity.
J Biol Chem
; 286(6): 4703-17, 2011 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21123183
2.
Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I).
Bioorg Med Chem Lett
; 21(18): 5633-7, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21798738
3.
Conserved amino acid networks involved in antibody variable domain interactions.
Proteins
; 76(1): 99-114, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19089973
4.
Anti-CD23 monoclonal antibody inhibits germline Cepsilon transcription in B cells.
Int Immunopharmacol
; 2(4): 453-61, 2002 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-11962725
5.
A stable IgG-like bispecific antibody targeting the epidermal growth factor receptor and the type I insulin-like growth factor receptor demonstrates superior anti-tumor activity.
MAbs
; 3(3): 273-88, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21393993
6.
Combination of two insulin-like growth factor-I receptor inhibitory antibodies targeting distinct epitopes leads to an enhanced antitumor response.
Mol Cancer Ther
; 9(9): 2593-604, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20716637
7.
Characterization of inhibitory anti-insulin-like growth factor receptor antibodies with different epitope specificity and ligand-blocking properties: implications for mechanism of action in vivo.
J Biol Chem
; 284(15): 10254-67, 2009 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19211557
8.
Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells.
Biotechnol Bioeng
; 97(4): 877-92, 2007 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17099908
9.
Targeting the lymphotoxin-beta receptor with agonist antibodies as a potential cancer therapy.
Cancer Res
; 66(19): 9617-24, 2006 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17018619
10.
Anti-CD23 monoclonal antibody, lumiliximab, inhibited allergen-induced responses in antigen-presenting cells and T cells from atopic subjects.
J Allergy Clin Immunol
; 116(4): 780-8, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16210051
11.
Novel antibody hinge regions for efficient production of CH2 domain-deleted antibodies.
J Biol Chem
; 280(50): 41494-503, 2005 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-16221669
12.
Future of monoclonal antibodies in the treatment of hematologic malignancies.
Cancer Control
; 9(2): 152-66, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-11965235