Detalhe da pesquisa
1.
Adjuvant Auger Electron-Emitting Radioimmunotherapy with [111In]In-DOTA-Panitumumab in a Mouse Model of Local Recurrence and Metastatic Progression of Human Triple-Negative Breast Cancer.
Mol Pharm
; 20(12): 6407-6419, 2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37983089
2.
Treatment of Orthotopic U251 Human Glioblastoma Multiforme Tumors in NRG Mice by Convection-Enhanced Delivery of Gold Nanoparticles Labeled with the ß-Particle-Emitting Radionuclide, 177Lu.
Mol Pharm
; 20(1): 582-592, 2023 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36516432
3.
Panitumumab-DOTA-111In: An Epidermal Growth Factor Receptor Targeted Theranostic for SPECT/CT Imaging and Meitner-Auger Electron Radioimmunotherapy of Triple-Negative Breast Cancer.
Mol Pharm
; 19(10): 3652-3663, 2022 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35926098
4.
90Y-Labeled Gold Nanoparticle Depot (NPD) Combined with Anti-PD-L1 Antibodies Strongly Inhibits the Growth of 4T1 Tumors in Immunocompetent Mice and Induces an Abscopal Effect on a Distant Non-Irradiated Tumor.
Mol Pharm
; 19(11): 4199-4211, 2022 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36287201
5.
Changing Surface Polyethylene Glycol Architecture Affects Elongated Nanoparticle Penetration into Multicellular Tumor Spheroids.
Biomacromolecules
; 23(8): 3296-3307, 2022 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35816453
6.
Site-Specific Conjugation of Metal-Chelating Polymers to Anti-Frizzled-2 Antibodies via Microbial Transglutaminase.
Biomacromolecules
; 22(6): 2491-2504, 2021 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33961407
7.
Dual-Receptor-Targeted (DRT) Radiation Nanomedicine Labeled with 177Lu Is More Potent for Killing Human Breast Cancer Cells That Coexpress HER2 and EGFR Than Single-Receptor-Targeted (SRT) Radiation Nanomedicines.
Mol Pharm
; 17(4): 1226-1236, 2020 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32022567
8.
Functionalization of Cellulose Nanocrystals with POEGMA Copolymers via Copper-Catalyzed Azide-Alkyne Cycloaddition for Potential Drug-Delivery Applications.
Biomacromolecules
; 21(6): 2014-2023, 2020 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32364706
9.
Radioimmunotherapy of PANC-1 Human Pancreatic Cancer Xenografts in NRG Mice with Panitumumab Modified with Metal-Chelating Polymers Complexed to 177Lu.
Mol Pharm
; 16(2): 768-778, 2019 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30589553
10.
MicroSPECT/CT Imaging of Cell-Line and Patient-Derived EGFR-Positive Tumor Xenografts in Mice with Panitumumab Fab Modified with Hexahistidine Peptides To Enable Labeling with 99mTc(I) Tricarbonyl Complex.
Mol Pharm
; 16(8): 3559-3568, 2019 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31242384
11.
CD16+NK-92 and anti-CD123 monoclonal antibody prolongs survival in primary human acute myeloid leukemia xenografted mice.
Haematologica
; 103(10): 1720-1729, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29976748
12.
Positron-Emission Tomography of HER2-Positive Breast Cancer Xenografts in Mice with 89Zr-Labeled Trastuzumab-DM1: A Comparison with 89Zr-Labeled Trastuzumab.
Mol Pharm
; 15(8): 3383-3393, 2018 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29957952
13.
Panitumumab Modified with Metal-Chelating Polymers (MCP) Complexed to 111In and 177Lu-An EGFR-Targeted Theranostic for Pancreatic Cancer.
Mol Pharm
; 15(3): 1150-1159, 2018 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29314858
14.
Molecular imaging in drug development: Update and challenges for radiolabeled antibodies and nanotechnology.
Methods
; 130: 23-35, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28743635
15.
64Cu-Labeled Trastuzumab Fab-PEG24-EGF Radioimmunoconjugates Bispecific for HER2 and EGFR: Pharmacokinetics, Biodistribution, and Tumor Imaging by PET in Comparison to Monospecific Agents.
Mol Pharm
; 14(2): 492-501, 2017 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28049295
16.
Local Radiation Treatment of HER2-Positive Breast Cancer Using Trastuzumab-Modified Gold Nanoparticles Labeled with 177Lu.
Pharm Res
; 34(3): 579-590, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27987070
17.
Stability and Biodistribution of Thiol-Functionalized and (177)Lu-Labeled Metal Chelating Polymers Bound to Gold Nanoparticles.
Biomacromolecules
; 17(4): 1292-302, 2016 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26974228
18.
Advancing novel molecular imaging agents from preclinical studies to first-in-humans phase I clinical trials in academia--a roadmap for overcoming perceived barriers.
Bioconjug Chem
; 26(4): 625-32, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25781873
19.
Radiation Nanomedicine for EGFR-Positive Breast Cancer: Panitumumab-Modified Gold Nanoparticles Complexed to the ß-Particle-Emitter, (177)Lu.
Mol Pharm
; 12(11): 3963-72, 2015 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26402157
20.
Trastuzumab Labeled to High Specific Activity with (111)In by Site-Specific Conjugation to a Metal-Chelating Polymer Exhibits Amplified Auger Electron-Mediated Cytotoxicity on HER2-Positive Breast Cancer Cells.
Mol Pharm
; 12(6): 1951-60, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25919639