Assessment of Cardiorespiratory and Metabolic Contributions in an Extreme Intensity CrossFit® Benchmark Workout.

Our purpose was to characterize the oxygen uptake kinetics (VO2), energy systems contributions and total energy expenditure during a CrossFit® benchmark workout performed in the extreme intensity domain. Fourteen highly trained male CrossFitters, aged 28.3 ± 5.4 years, with height 177.8 ± 9.4 cm, body mass 87.9 ± 10.5 kg and 5.6 ± 1.8 years of training experience, performed the Isabel workout at maximal exertion. Cardiorespiratory variables were measured at baseline, during exercise and the recovery period, with blood lactate and glucose concentrations, including the ratings of perceived exertion, measured pre- and post-workout. The Isabel workout was 117 ± 10 s in duration and the VO2 peak was 47.2 ± 4.7 mL·kg-1·min-1, the primary component amplitude was 42.0 ± 6.0 mL·kg-1·min-1, the time delay was 4.3 ± 2.2 s and the time constant was 14.2 ± 6.0 s. The accumulated VO2 (0.6 ± 0.1 vs. 4.8 ± 1.0 L·min-1) value post-workout increased substantially when compared to baseline. Oxidative phosphorylation (40%), glycolytic (45%) and phosphagen (15%) pathways contributed to the 245 ± 25 kJ total energy expenditure. Despite the short ~2 min duration of the Isabel workout, the oxygen-dependent and oxygen-independent metabolism energy contributions to the total metabolic energy release were similar. The CrossFit® Isabel requires maximal effort and the pattern of physiological demands identifies this as a highly intensive and effective workout for developing fitness and conditioning for sports.

Acute Responses in Blood Flow Restriction Low-intensity Aerobic Training: A Meta-analysis.

The purpose was to determine the effect low-intensity training with blood flow restriction (LI-BFR) versus high-intensity aerobic training (HIT) on acute physiological and perceptual responses. The Cumulative Index to Nursing and Allied Health Literature, National Library of Medicine, Scopus, SPORTDiscus and Web of Science databases and the reference list of eligible studies were consulted to identify randomized experimental studies, published until July 4, 2022, that analyzed physiological or perceptual responses between LI-BFR versus HIT in healthy young individuals. Mean difference (MD) and standardized mean difference (SMD) were used as effect estimates and random effects models were applied in all analyses. Twelve studies were included in this review. During exercise sessions, HIT promoted higher values of heart rate (MD=28.9 bpm; p<0.00001; I 2 =79%), oxygen consumption (SMD=4.01; p<0.00001; I 2 =83%), ventilation (MD=48.03 l/min; p=0.0001; I 2 =97%), effort (SMD=1.54; p=0.003; I 2 =90%) and blood lactate (MD=3.85 mmol/L; p=0.002; I 2 =97%). Perception of pain/discomfort was lower in HIT (SMD=-1.71; p=0.04; I 2 =77.5%). In conclusion, LI-BFR promotes less pronounced physiological responses than HIT but with greater perception of pain.

Comparison of brown adipose tissue activation detected by infrared thermography in men with vs without metabolic syndrome.

BACKGROUND: Brown adipose tissue (BAT) high density of mitochondria and its thermogenic characteristics promote the dissipation of chemical energy in the form of heat, increasing body caloric expenditure, decreasing plasma levels of lipids and glucose (GL). This makes BAT a potential therapeutic target of Metabolic Syndrome (MetS). Position Emission Tomography Scanning (PET-CT) is the gold standard for estimating BAT, but it has several limitations, including high cost and high emission of radiation. On the other hand, Infrared Thermography (IRT) is considered a simpler, cheaper and non-invasive method to detect BAT. OBJECTIVE: The aim of this study was to compare BAT activation through IRT and cold stimulation in men diagnosed without and with MetS. METHODS: Sample of 124 (35.3 ± 9.4 years old) men was evaluated of body composition, anthropometric measurements and dual X-ray absorptiometry (DXA) hemodynamics, biochemical tests and body skin temperature acquisition. The Student t-test with subsequent effect size by (d) Cohen and two-way repeated measures ANOVA with Tukey post-hoc comparisons were conducted. Level of significance was p < 0.05. RESULTS: There was significant interaction between group factor (MetS) vs group moment (BAT activation) in supraclavicular skin temperatures right side (maximum (F(1,122) = 10.4, p < 0.002, η2 = 0.062), mean (F(1.122) = 13.0, p < 0.001, η2 = 0.081) and minimal (F(1,122) = 7.9, p < 0.006, η2 = 0.052)) and left side maximum (F(1,122) = 7.7, p < 0.006, η2 = 0.048), mean (F(1.122) = 13.0, p < 0.037, η2 = 0.007) and minimal (F(1,122) = 9.8, p < 0.002, η2 = 0.012)). The MetS risk factor group didn't present significant increase of SCV temperature BAT after cold stimulation. CONCLUSION: Men diagnosed with MetS risk factors seem to activate less BAT, when exposed to cold stimulation, compared to group without MetS risk factor.

Effect of Rest Interval Between Sets in the Muscle Function During a Sequence of Strength Training Exercises for the Upper Body.

ABSTRACT: Matos, F, Ferreira, B, Guedes, J, Saavedra, F, Reis, VM, and Vilaça-Alves, J. Effect of rest interval between sets in the muscle function during a sequence of strength training exercises for the upper body. J Strength Cond Res 35(6): 1628-1635, 2021-The objective of this study was to observe the ideal recovery time between sets and exercises, for both chest and back, which allowed for maintaining muscle function with the initial load previously established. Sixty young men recreationally trained in strength training (ST) were divided into 2 groups: (a) 30 subjects were included in the GC group (the group that performed ST for the chest) and (b) 30 subjects were included in the GB group (the group that performed ST for the back). Each group was submitted to 3 experimental sessions, performing an ST sequence with 3 sets of 8 repetition maximum: GC performed a chest barbell press (CBP), an inclined CBP, and a chest butterfly; GB performed a lat pull-down, a back row, and a shoulder extension on the high pulley. The experimental sessions differed in rest time between sets performed (60, 90, and 120 seconds). For both groups in each sequence, significantly higher numbers of repetitions were observed with the rest time of 120 seconds relative to the rest time of 90 seconds (p = 0.004), 120 seconds in relation to the rest time of 60 seconds (p = 0.001), and in the rest interval of 90 seconds in relation to the rest time of 60 seconds (p < 0.0001). The results showed that 120 seconds was sufficient to maintain muscle function and perform the total number of repetitions per set. The data seem to show that for the ST methodology applied, it is not appropriate to assume that a certain relative intensity will translate into a similar number of repetitions in different exercises, especially with shorter rest intervals such as 60 and 90 seconds.

Ischemic Preconditioning Improves Resistance Training Session Performance.

ABSTRACT: da Silva Novaes, J, da Silva Telles, LG, Monteiro, ER, da Silva Araujo, G, Vingren, JL, Silva Panza, P, Reis, VM, Laterza, MC, and Vianna, JM. Ischemic preconditioning improves resistance training session performance. J Strength Cond Res 35(11): 2993-2998, 2021-The aim of this study was to investigate the acute effect of ischemic preconditioning (IPC) in a resistance exercise (RE) training session on the number of repetitions performed, total volume, and rating of perceived exertion in recreationally trained and normotensive men. Sixteen recreationally trained and normotensive men completed 3 RE sessions in a counterbalanced and randomized order: (a) IPC protocol using 220 mm Hg followed by RE (IPC), (b) IPC cuff control protocol with 20 mm Hg followed by RE (CUFF), and (c) no IPC (control) followed by RE (CON). RE was performed with 3 sets of each exercise (bench press, leg press, lateral pulldown, hack machine squat, shoulder press, and Smith back squat) until concentric muscular failure, at 80% of one repetition maximum, with 90 seconds of rest between sets and 2 minutes of rest between exercises. Ischemic preconditioning and CUFF consisted of 4 cycles of 5 minutes of occlusion/low pressure alternating with 5 minutes of no occlusion (0 mm Hg) using a pneumatic tourniquet applied around the subaxillary region of the upper arm. For each condition, the number of repetitions completed, total volume of work performed, and rating of perceived exertion were determined. No significant difference was found for rating of perceived exertion between any experimental protocol. Ischemic preconditioning significantly (p < 0.05) increased the number of repetitions across exercises. Consequently, total volume performed (sum of total number of repetitions x load for each exercise) was significantly higher in IPC (46,170 kg) compared with CON (34,069 kg) and CUFF (36,590 kg) across all exercises. This work may have important implications for athletic populations because it demonstrates increase in muscle performance outcomes during a single RE session. Therefore, performing IPC before RE could be an important exercise prescription recommendation to increase maximum repetition performance and total volume of work performed and thus potentially increase desired training adaptations (i.e., strength and hypertrophy).

Comparison of Post-Exercise Hypotension Responses in Paralympic Powerlifting Athletes after Completing Two Bench Press Training Intensities.

Background and objective: Post-exercise hypotension, the reduction of blood pressure after a bout of exercise, is of great clinical relevance. Resistance exercise training is considered an important contribution to exercise training programs for hypertensive individuals and athletes. In this context, post-exercise hypotension could be clinically relevant because it would maintain blood pressure of hypertensive individuals transiently at lower levels during day-time intervals, when blood pressure is typically at its highest levels. The aim of this study was to compare the post-exercise cardiovascular effects on Paralympic powerlifting athletes of two typical high-intensity resistance-training sessions, using either five sets of five bench press repetitions at 90% 1 repetition maximum (1RM) or five sets of three bench press repetitions at 95% 1RM. Materials and Methods: Ten national-level Paralympic weightlifting athletes (age: 26.1 ± 6.9 years; body mass: 76.8 ± 17.4 kg) completed the two resistance-training sessions, one week apart, in a random order. Results: Compared with baseline values, a reduction of 5-9% in systolic blood pressure was observed after 90% and 95% of 1RM at 20-50 min post-exercise. Furthermore, myocardial oxygen volume and double product were only significantly increased immediately after and 5 min post-exercise, while the heart rate was significantly elevated after the resistance training but decreased to baseline level by 50 min after training for both training conditions. Conclusions: A hypotensive response can be expected in elite Paralympic powerlifting athletes after typical high-intensity type resistance-training sessions.

The Influence of Warm-Up on Body Temperature and Strength Performance in Brazilian National-Level Paralympic Powerlifting Athletes.

Background and Objectives: The effects of warm-up in athletic success have gained strong attention in recent studies. There is, however, a wide gap in awareness of the warm-up process to be followed, especially in Paralympic powerlifting (PP) athletes. This study aimed to analyze different types of warm-up on the physical performance of PP athletes. Materials and Methods: The sample consisted of 12 elite Brazilian PP male athletes (age, 24.14 ± 6.21 years; bodyweight, 81.67 ± 17.36 kg). The athletes performed maximum isometric force (MIF), rate of force development (RFD), and speed test (Vmax) in three different methods of warm-up. Tympanic temperature was used to estimate the central body temperature. Results: A significant difference was observed for MIF in the without warm-up (WW) condition in relation to the traditional warm-up (TW) and stretching warm-up (SW) (p = 0.005, η2p = 0.454, high effect). On the contrary, no significant differences were observed in RFD, fatigue index (FI) and time in the different types of warm up (p > 0.05). Furthermore, no significant differences were observed in relation to the maximum repetition (p = 0.121, η2p = 0.275, medium effect) or the maximum speed (p = 0.712, η2p = 0.033, low effect) between the different types of warm up. In relation to temperature, significant differences were found for the TW in relation to the "before" and "after" conditions. In addition, differences were found between WW in the "after" condition and SW. In addition, WW demonstrated a significant difference in relation to TW in the "10 min later" condition (F = 26.87, p = 0.05, η2p = 0.710, high effect). Conclusions: The different types of warm-up methods did not seem to provide significant differences in the force indicators in elite PP athletes.

Cardiac surgery for Chagas disease.

Although Chagas disease is a rare entity in North America, it is associated with significant cardiac morbidity. It is estimated that 20-30% of those who are infected will eventually develop cardiovascular disease secondary to Chagas disease. We review the literature and share our experience on the surgical management of this challenging patient population.

Effect of Cold-Water Immersion on Elbow Flexors Muscle Thickness After Resistance Training.

Matos, F, Neves, EB, Rosa, C, Reis, VM, Saavedra, F, Silva, S, Tavares, F, and Vilaça-Alves, J. Effect of cold-water immersion on elbow flexors muscle thickness after resistance training. J Strength Cond Res 32(3): 756-763, 2018-Cold-water immersion (CWI) is commonly applied to speed up the recovery process after exercise. Muscle damage may induce a performance reduction and consequence of the intramuscular pressure induced by the muscular swelling. The aim of the study was to verify the CWI effects on muscle thickness (MT) behavior of the elbow flexors after a strength training (ST) protocol. Eleven men were submitted to an ST, performed in 2 different weeks. In one of the weeks, subjects experienced a passive recovery. In the other, subjects were submitted to a CWI (20 minutes at 5-10° C). Ultrasound (US) images were taken before, after, as well as 24, 48, and 72 hours after exercise, to evaluate the MT. Muscle thickness in both exercise arm (EA) and control arm (CA) was significantly higher 48 and 72 hours after exercise when subjects were submitted to a passive recovery compared with the CWI (p = 0.029, p = 0.028, p = 0.009, and p = 0.001, 48 hours, 72 hours, EA, and CA, respectively). When each arm was analyzed with or without using CWI individually, significantly higher MT was observed in the EA with CWI: before exercise in relation to 72 hours after exercise (p = 0.042) and after exercise in relation to the other measurements (p = 0.003, p = 0.003, p = 0.038, and p < 0.0001, before exercise and 24, 48, 72 hours after exercise, respectively). The evaluation of MT by US provides evidence that CWI after ST (and 24 hours after exercise) may reduce muscle swelling in the postexercise days when compared with a passive recovery. Seems to be a paradox between the uses of CWI for an acute reduction of muscle swelling.

Cross-sectional, school-based study of 14-19 year olds showed that raised blood pressure was associated with obesity and abdominal obesity.

AIM: Gaining weight has been directly associated with an increased probability of developing high blood pressure (HBP) and metabolic abnormalities. We examined the independent and combined effects of overweight, obesity and abdominal obesity on blood pressure in adolescents. METHODS: This cross-sectional school-based study evaluated 869 adolescents (53.4% girls) from 14 to 19 years of age, and the data were collected in 2013 in the city of Imperatriz, Maranhão, Brazil. The outcome was HBP. The independent variables were overweight and obesity classified by body mass index, abdominal obesity classified by the waist-to-height ratio and the combination of obesity and overweight and abdominal obesity. The potential confounding variables were age, the socio-economic status of the family, parental education, type of school and physical activity levels. RESULTS: The prevalence ratios of HBP were higher when male and female adolescents were overweight (1.61-3.11), generally obese (3.20-4.70), had abdominal obesity (2.18-3.02) and were both generally obese and had abdominal obesity (3.28-5.16) compared with normal weight adolescents. CONCLUSION: Obesity or abdominal obesity increased the risk of HBP in adolescents aged 14-19. However, adolescents who were both generally obese and had abdominal obesity showed an even higher risk of having HBP.

Robotic paravertebral schwannoma resection at extreme locations of the thoracic cavity.

Solitary paravertebral schwannomas in the thoracic spine and lacking an intraspinal component are uncommon. These benign nerve sheath tumors are typically treated using complete resection with an excellent outcome. Resection of these tumors is achieved by an anterior approach via open thoracotomy or minimally invasive thoracoscopy, by a posterior approach via laminectomy, or by a combination of both approaches. These tumors most commonly occur in the midthoracic region, for which surgical removal is usually straightforward. The authors of this report describe 2 cases of paravertebral schwannoma at extreme locations of the posterior mediastinum, one at the superior sulcus and the other at the inferior sulcus of the thoracic cavity, for which the usual surgical approaches for safe resection can be challenging. The tumors were completely resected with robot-assisted thoracoscopic surgery. This report suggests that single-stage anterior surgery for this type of tumor in extreme locations is safe and effective with this novel minimally invasive technique.

Exercise prescription for patients with type 2 diabetes-a synthesis of international recommendations: narrative review.

BACKGROUND: Physical activity is a cornerstone of type 2 diabetes treatment and control. AIM: We analysed and synthesised the guidelines and recommendations issued by scientific organisations, regarding exercise prescription for patients with type 2 diabetes. METHOD: A systematic bibliographic search in Pubmed, Web of Science and Scopus databases was conducted. Clinical guidelines from major international scientific organisations in the field of diabetology, endocrinology, cardiology, public health and sports medicine were also considered. 11 publications were selected. RESULTS: Published guidelines recommend a weekly accumulation of a minimum of 150 min of aerobic exercise at moderate-to-vigorous intensity spread over a minimum of 3 days per week. Resistance exercise for muscle strengthening is also recommended at least 2 days a week. Flexibility exercises may complement other types of exercise. Combining aerobic and resistance exercise within the same exercise session is recommended by most guidelines. CONCLUSIONS: Exercise prescription for individuals with type 2 diabetes should include specific information on the type, mode, duration, intensity and weekly frequency. The exercise strategies must be adapted for each individual, based on comorbidities, contraindications and realistic personal goals.

A Randomized Trial Investigating the Influence of Strength Training on Quality of Life in Ischemic Stroke.

BACKGROUND: Strength training post stroke is widely acknowledged as an important part of a rehabilitation program. Muscle strength has been shown to be a significant contributor to physical disability after stroke, which in turn has an immense impact on the reintegration of patients into society, affecting their quality of life. OBJECTIVE: This was a randomized intervention trial to determine the effect of a resistance training program on the quality of life in patients with stroke. METHODS: An experimental group (EG), consisting of 11 subjects aged 51.7 ± 8.0 years, and a control group (CG), consisting of 13 subjects aged 52.5 ± 7.7 years, were studied before and after 12 weeks. EG underwent 12 weeks of strength training three times a week. The CG did not undergo strength training during the 12-week study period. RESULTS: There was a significant increase in quality of life from pre-test to post-test (Δ% = 21.47%; p = 0.021) in EG. There were significant differences in all indicators of quality of life between groups at 12 weeks. There were greater gains in strength in EG than in CG (p ≤ 0.05). There was a negative correlation between the strength gains as determined with the 1RM test and the quality of life, especially in lower limb exercises. CONCLUSION: The results of this study indicate that there was an improvement in the measures of strength in EG, and that there was a correlation between improvements in strength and quality of life in these patients who had previously suffered a stroke at least one year prior to study.

Influence of Rest Interval Length Between Sets on Blood Pressure and Heart Rate Variability After a Strength Training Session Performed By Prehypertensive Men.

Figueiredo, T, Willardson, JM, Miranda, H, Bentes, CM, Machado Reis, V, Freitas de Salles, B, and Simão, R. Influence of rest interval length between sets on blood pressure and heart rate variability after a strength training session performed by prehypertensive men. J Strength Cond Res 30(7): 1813-1824, 2016-The purposes of this study were to compare the effects of 2 different rest interval lengths between sets and exercises during strength training (ST) on blood pressure (BP) and heart rate variability (HRV) in prehypertensive trained men, and to verify how HRV influences BP. Eleven volunteer subjects (age: 26.1 ± 3.6 years; body mass: 74.1 ± 7.9 kg; height: 172.1 ± 4.1 cm; % body fat: 18.3 ± 6.3; ST experience: 1.7 ± 0.8 years) participated in this study. After assessing one repetition maximum (1RM) loads for the free weight bench press, lat pull-down, shoulder press, biceps curl, triceps extension, leg press, leg extension, and leg curl exercises; subjects performed 2 sessions with different rest intervals between sets and exercises in random order and 72 hours apart. Each ST session consisted of performing 3 sets of eight to 10 repetitions at 70% of a 1RM for each exercise, with either 1-minute (sequence 1 [SEQ1]) or 2-minute (sequence 2 [SEQ2]) rest intervals between sets and exercises, respectively. Before and after each session, BP and HRV (low frequency band, high frequency [HF] band, and square root of the mean squared difference of successive RR-interval index) were tracked for 60 minutes. The results demonstrated a postexercise hypotensive response (PEH) after both rest interval conditions (p ≤ 0.05). Additionally, increases in cardiac stress were noted after SEQ1, with a greater withdrawal in parasympathetic activity vs. baseline as noted in the HF band at 1-, 10-, and 20-minute postexercise (p ≤ 0.05). These results indicate that both sequences provided an effective stimulus for a PEH. Therefore, strength and conditioning professionals may prescribe 1- or 2-minute rest between sets and exercises when the goal is to reduce BP after training sessions. However, resting 1 minute between sets and exercises was associated with greater cardiac stress, and so this may necessitate prescription of longer rest intervals between sets and exercises when working with individuals who have been diagnosed with cardiovascular dysfunction.

Influence of Load Intensity on Postexercise Hypotension and Heart Rate Variability after a Strength Training Session.

The purpose of this study was to compare blood pressure and heart rate variability (HRV) responses in trained men after strength training (ST) sessions with loads of 60, 70, and 80% of a 1 repetition maximum (1RM). Eleven men (age: 26.1 ± 3.6 years; body mass: 74.1 ± 8.1 kg; height: 172.0 ± 4.0 cm; body mass index: 25.0 ± 1.96 kg·m(-2); %G: 18.3 ± 6.4) with at least 6-month ST experience participated in this study. After assessment of 1RM loads for the bench press (BP), lat pull-down (LPD), shoulder press (SP), biceps curl (BC), triceps extension (TE), leg press (LP), leg extension (LE), and leg curl (LC), subjects performed 3 experimental sessions in random order. During each experimental session, subjects performed 3 sets of 8-10 repetitions at 60, 70, or 80% of 1RM loads, with 2-minute rest intervals between sets and exercises. All experimental sessions were performed in the following exercise order: BP, LPD, SP, BC, TE, LP, LE, and LC. Before and for 1 hour after each experimental session, blood pressure and HRV were tracked. The results demonstrated a greater duration of postexercise hypotension (PEH) after the 70% of 1RM session vs. the 60 or 80% of 1RM session. These results indicate that the load/volume associated with completion of 8-10 repetitions at 70% of 1RM load may provide the best stimulus for the PEH response when compared with training with a 60 or 80% of 1RM loads. In conclusion, strength and conditioning professionals may prescribe exercises with 60, 70, and 80% of 1RM loads if the intent is to elicit an acute decrease in blood pressure after an ST session; however, 70% of 1RM provides a longer PEH.

Order effects of combined strength and endurance training on testosterone, cortisol, growth hormone, and IGF-1 binding protein 3 in concurrently trained men.

Concurrent training (CT) has been widely used in fitness centers to simultaneously optimize cardiovascular and neuromuscular fitness, and induce a high-energy expenditure. Therefore, the aim of this study was to compare the acute effects of 2 different orders of CT on hormonal responses in concurrently trained men. Fourteen men (mean ± SD: 24.7 ± 5.1 years) were randomly divided into 2 groups: endurance training followed by strength (ES, n = 7) and strength training followed by endurance (SE, n = 7). Serum concentrations of testosterone, cortisol, growth hormone, and IGF-1 binding protein 3 (IGFBP-3) were measured before and after both training orders. A significant interaction between exercise order and time was only found in the IGFBP-3 levels (p = 0.022). The testosterone and IGFBP-3 concentrations significantly increased in the ES group after the exercise trainings (57.7 ± 35.1%, p = 0.013 and 17.0 ± 15.5%, p = 0.032, respectively) but did not change significantly in the SE group (15.5 ± 36.6%, p = 0.527 and -4.2 ± 13.9%, p = 0.421, respectively). Conversely, cortisol and growth hormone concentrations significantly increased in both ES (169.2 ± 191.0%, p = 0.021 and 13,296.8 ± 13,009.5%, p = 0.013, respectively) and SE (92.2 ± 81.5%, p = 0.017 and 12,346.2 ± 9714.1%, p = 0.001, respectively) groups compared with baseline values. No significant correlations were found between the changes in the hormonal concentrations. In conclusion, these results suggest that immediately postexercise testosterone and IGFPB-3 responses are significantly increased only after the ES order. Therefore, an ES training order should be prescribed if the main focus of the training intervention is to induce an acute postexercise anabolic environment.

Influence of number of sets on blood pressure and heart rate variability after a strength training session.

The purpose of this study was to compare the acute effects of 1, 3, and 5 sets of strength training (ST), on heart rate variability (HRV) and blood pressure. Eleven male volunteers (age: 26.1 ± 3.6 years; body mass: 74.1 ± 8.1 kg; height: 172 ± 4 cm) with at least 6 months previous experience in ST participated in the study. After determining the 1 repetition maximum (1RM) load for the bench press (BP), lat pull down (LPD), shoulder press (SP), biceps curl (BC), triceps extension (TE), leg press (LP), leg extension (LE), and leg curl (LC), the participants performed 3 different exercise sequences in a random order and 72 hours apart. During the first sequence, subjects performed a single set of 8-10 repetitions, at 70% 1RM, and with 2-minute rest interval between exercises. Exercises were performed in the following order: BP, LPD, SP, BC, TE, LP, LE, and LC. During the second sequence, subjects performed the same exercise sequence, with the same intensity, 2-minute rest interval between sets and exercises, but with 3 consecutive sets of each exercise. During the third sequence, the same protocol was followed but with 5 sets of each exercise. Before and after the training sessions, blood pressure and HRV were measured. The statistical analysis demonstrated a greater duration of postexercise hypotension after the 5-set program vs. the 1 set or 3 sets (p ≤ 0.05). However, the 5-set program promoted a substantial cardiac stress, as demonstrated by HRV (p ≤ 0.05). These results indicate that 5 sets of 8-10 repetitions at 70% 1RM load may provide the ideal stimulus for a postexercise hypotensive response. Therefore, ST composed of upper- and lower-body exercises and performed with high volumes are capable of producing significant and extended postexercise hypotensive response. In conclusion, strength and conditioning professionals can prescribe 5 sets per exercises if the goal is to reduce blood pressure after training. In addition, these findings may have importance, specifically in the early phase of high blood pressure development, but more research is needed in hypertensive populations to validate this hypothesis.