Detalhe da pesquisa
1.
Disclosing the Antifungal Mechanisms of the Cyclam Salt H4[H2(4-CF3PhCH2)2Cyclam]Cl4 against Candida albicans and Candida krusei.
Int J Mol Sci
; 25(10)2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38791254
2.
Autophagy (but not metabolism) is a key event in mitoxantrone-induced cytotoxicity in differentiated AC16 cardiac cells.
Arch Toxicol
; 97(1): 201-216, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36216988
3.
The role of inflammation and antioxidant defenses in the cardiotoxicity of doxorubicin in elderly CD-1 male mice.
Arch Toxicol
; 97(12): 3163-3177, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37676301
4.
Assessment of the Permeability of 3,4-Methylenedioxypyrovalerone (MDPV) across the Caco-2 Monolayer for Estimation of Intestinal Absorption and Enantioselectivity.
Int J Mol Sci
; 24(3)2023 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36768999
5.
Study Models of Drug-Drug Interactions Involving P-Glycoprotein: The Potential Benefit of P-Glycoprotein Modulation at the Kidney and Intestinal Levels.
Molecules
; 28(22)2023 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38005253
6.
Semi-Preparative Separation, Absolute Configuration, Stereochemical Stability and Effects on Human Neuronal Cells of MDPV Enantiomers.
Molecules
; 28(5)2023 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36903367
7.
Vitamin D: sources, physiological role, biokinetics, deficiency, therapeutic use, toxicity, and overview of analytical methods for detection of vitamin D and its metabolites.
Crit Rev Clin Lab Sci
; 59(8): 517-554, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35575431
8.
Synthetic Cathinones: Recent Developments, Enantioselectivity Studies and Enantioseparation Methods.
Molecules
; 27(7)2022 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35408456
9.
S-(+)-Pentedrone and R-(+)-methylone as the most oxidative and cytotoxic enantiomers to dopaminergic SH-SY5Y cells: Role of MRP1 and P-gp in cathinones enantioselectivity.
Toxicol Appl Pharmacol
; 416: 115442, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33609514
10.
The Secretome of Human Neonatal Mesenchymal Stem Cells Modulates Doxorubicin-Induced Cytotoxicity: Impact in Non-Tumor Cells.
Int J Mol Sci
; 22(23)2021 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34884877
11.
Enantioselectivity in Drug Pharmacokinetics and Toxicity: Pharmacological Relevance and Analytical Methods.
Molecules
; 26(11)2021 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34070985
12.
Enantioselectivity on the absorption of methylone and pentedrone using Caco-2 cell line: Development and validation of an UHPLC method for cathinones quantification.
Toxicol Appl Pharmacol
; 395: 114970, 2020 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32234388
13.
P-glycoprotein activation by 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5) in rat distal ileum: ex vivo and in vivo studies.
Toxicol Appl Pharmacol
; 386: 114832, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31756430
14.
Pharmacokinetics and Toxicokinetics Roles of Membrane Transporters at Kidney Level.
J Pharm Pharm Sci
; 23: 333-356, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32997956
15.
Mitoxantrone impairs proteasome activity and prompts early energetic and proteomic changes in HL-1 cardiomyocytes at clinically relevant concentrations.
Arch Toxicol
; 94(12): 4067-4084, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32894303
16.
Exploring the Multi-Target Performance of Mitochondriotropic Antioxidants against the Pivotal Alzheimer's Disease Pathophysiological Hallmarks.
Molecules
; 25(2)2020 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31936622
17.
Bioisosteric OH- to SH-replacement changes the antioxidant profile of ferulic acid.
Org Biomol Chem
; 17(44): 9646-9654, 2019 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31674614
18.
Insights into the Discovery of Novel Neuroprotective Agents: A Comparative Study between Sulfanylcinnamic Acid Derivatives and Related Phenolic Analogues.
Molecules
; 24(23)2019 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31810314
19.
Newly Synthesized Oxygenated Xanthones as Potential P-Glycoprotein Activators: In Vitro, Ex Vivo, and In Silico Studies.
Molecules
; 24(4)2019 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30781374
20.
Comprehensive review of cardiovascular toxicity of drugs and related agents.
Med Res Rev
; 38(4): 1332-1403, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29315692