Detalhe da pesquisa
1.
Macrocyclic biphenyl tetraoxazoles: synthesis, evaluation as G-quadruplex stabilizers and cytotoxic activity.
Bioorg Med Chem
; 21(15): 4511-20, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23787291
2.
Macrocyclic pyridyl polyoxazoles: structure-activity studies of the aminoalkyl side-chain on G-quadruplex stabilization and cytotoxic activity.
Molecules
; 18(10): 11938-63, 2013 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24077174
3.
A G-quadruplex stabilizer induces M-phase cell cycle arrest.
J Biol Chem
; 284(34): 22535-43, 2009 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-19531483
4.
Macrocyclic hexaoxazoles: Influence of aminoalkyl substituents on RNA and DNA G-quadruplex stabilization and cytotoxicity.
Bioorg Med Chem Lett
; 20(10): 3150-4, 2010 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20409709
5.
Defining the mode, energetics and specificity with which a macrocyclic hexaoxazole binds to human telomeric G-quadruplex DNA.
Nucleic Acids Res
; 35(10): 3272-86, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17452355
6.
The Hairpin Form of r(G4C2)exp in c9ALS/FTD Is Repeat-Associated Non-ATG Translated and a Target for Bioactive Small Molecules.
Cell Chem Biol
; 26(2): 179-190.e12, 2019 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30503283
7.
Targeting human telomeric G-quadruplex DNA with oxazole-containing macrocyclic compounds.
Biochimie
; 90(8): 1233-49, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18439430
8.
Lysinyl macrocyclic hexaoxazoles: synthesis and selective G-quadruplex stabilizing properties.
Bioorg Med Chem Lett
; 18(3): 913-7, 2008 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18248989
9.
Ring-closing metathesis for the synthesis of a highly G-quadruplex selective macrocyclic hexaoxazole having enhanced cytotoxic potency.
Bioorg Med Chem Lett
; 18(13): 3802-4, 2008 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18515097
10.
Macrocyclic pyridyl polyoxazoles: selective RNA and DNA G-quadruplex ligands as antitumor agents.
J Med Chem
; 53(9): 3632-44, 2010 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20359224
11.
Synthesis and G-quadruplex stabilizing properties of a series of oxazole-containing macrocycles.
Bioorg Med Chem Lett
; 16(15): 3891-5, 2006 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16735121
12.
Synthesis and biological activity of the tea catechin metabolites, M4 and M6 and their methoxy-derivatives.
Bioorg Med Chem Lett
; 15(4): 873-6, 2005 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15686878