Detalhe da pesquisa
1.
Suppression of superoxide/hydrogen peroxide production at mitochondrial site IQ decreases fat accumulation, improves glucose tolerance and normalizes fasting insulin concentration in mice fed a high-fat diet.
Free Radic Biol Med
; 204: 276-286, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37217089
2.
Superoxide produced by mitochondrial site IQ inactivates cardiac succinate dehydrogenase and induces hepatic steatosis in Sod2 knockout mice.
Free Radic Biol Med
; 164: 223-232, 2021 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33421588
3.
Profiling induction of cytochrome p450 enzyme activity by statins using a new liquid chromatography-tandem mass spectrometry cocktail assay in human hepatocytes.
Drug Metab Dispos
; 38(9): 1589-97, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20551241
4.
eIF2B activator prevents neurological defects caused by a chronic integrated stress response.
Elife
; 82019 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30624206
5.
Effect of gemfibrozil, rifampicin, or probenecid on the pharmacokinetics of the SGLT2 inhibitor empagliflozin in healthy volunteers.
Clin Ther
; 36(2): 280-90.e1, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24491572
6.
Paraoxonase (PON1 and PON3) Polymorphisms: Impact on Liver Expression and Atorvastatin-Lactone Hydrolysis.
Front Pharmacol
; 2: 41, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21852972
7.
A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes.
BMC Syst Biol
; 5: 66, 2011 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21548957
8.
Distinction between human cytochrome P450 (CYP) isoforms and identification of new phosphorylation sites by mass spectrometry.
J Proteome Res
; 7(11): 4678-88, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18828626