Detalhe da pesquisa
1.
The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma.
PLoS Genet
; 17(11): e1009868, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34752469
2.
Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis.
EMBO J
; 32(20): 2708-21, 2013 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24045232
3.
Sequential intravital imaging reveals in vivo dynamics of pancreatic tissue transplanted under the kidney capsule in mice.
Diabetologia
; 59(11): 2387-2392, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27443307
4.
Atypical teratoid/rhabdoid tumoroids reveal subgroup-specific drug vulnerabilities.
Oncogene
; 42(20): 1661-1671, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37020038
5.
Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label treatment.
Cell Genom
; 2(2): 100095, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35187519
6.
EWSR1-WT1 Target Genes and Therapeutic Options Identified in a Novel DSRCT In Vitro Model.
Cancers (Basel)
; 13(23)2021 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34885181
7.
In vivo cytidine base editing of hepatocytes without detectable off-target mutations in RNA and DNA.
Nat Biomed Eng
; 5(2): 179-189, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33495639
8.
Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-ß Resistance.
Cell Stem Cell
; 26(3): 431-440.e8, 2020 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32142663
9.
In vitro Generation of CRISPR-Cas9 Complexes with Covalently Bound Repair Templates for Genome Editing in Mammalian Cells.
Bio Protoc
; 9(1)2019 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30675496
10.
Treatment of a metabolic liver disease by in vivo genome base editing in adult mice.
Nat Med
; 24(10): 1519-1525, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30297904
11.
Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair.
Elife
; 72018 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29809142
12.
Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies.
Cell Rep
; 24(5): 1363-1376, 2018 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30067989
13.
Growth of Epithelial Organoids in a Defined Hydrogel.
Adv Mater
; 30(43): e1801621, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30203567
14.
Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential.
Stem Cell Reports
; 10(3): 712-724, 2018 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29539434
15.
Generation of L cells in mouse and human small intestine organoids.
Diabetes
; 63(2): 410-20, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24130334