Detalhe da pesquisa
1.
A20 controls RANK-dependent osteoclast formation and bone physiology.
EMBO Rep
; 23(12): e55233, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36194667
2.
Structure-Based Discovery of Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-Induced Osteoclastogenesis Inhibitors.
Int J Mol Sci
; 24(14)2023 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37511048
3.
Proteomic Identification of the SLC25A46 Interactome in Transgenic Mice Expressing SLC25A46-FLAG.
J Proteome Res
; 21(2): 375-394, 2022 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34983179
4.
Transgenic Mice Carrying GLUD2 as a Tool for Studying the Expressional and the Functional Adaptation of this Positive Selected Gene in Human Brain Evolution.
Neurochem Res
; 44(1): 154-169, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29777493
5.
Cheminformatics-aided discovery of small-molecule Protein-Protein Interaction (PPI) dual inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).
PLoS Comput Biol
; 13(4): e1005372, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28426652
6.
A RANKL G278R mutation causing osteopetrosis identifies a functional amino acid essential for trimer assembly in RANKL and TNF.
Hum Mol Genet
; 21(4): 784-98, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22068587
7.
2,2'-Dihydroxybenzophenones and their carbonyl N-analogues as inhibitor scaffolds for MDR-involved human glutathione transferase isoenzyme A1-1.
Bioorg Med Chem
; 22(15): 3957-70, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25002233
8.
A statistical approach for optimization of RANKL overexpression in Escherichia coli: purification and characterization of the protein.
Protein Expr Purif
; 90(1): 9-19, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23623854
9.
Phosphotungstic acid-enhanced microcomputed tomography for quantitative visualization of mouse mammary gland morphology.
J Med Imaging (Bellingham)
; 10(Suppl 2): S22402, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36825256
10.
Α Humanized RANKL Transgenic Mouse Model of Progestin-Induced Mammary Carcinogenesis for Evaluation of Novel Therapeutics.
Cancers (Basel)
; 15(15)2023 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37568820
11.
Dexamethasone Administration in Mice Leads to Less Body Weight Gain over Time, Lower Serum Glucose, and Higher Insulin Levels Independently of NRF2.
Antioxidants (Basel)
; 11(1)2021 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35052508
12.
Discovery of Small-Molecule Inhibitors of Receptor Activator of Nuclear Factor-κB Ligand with a Superior Therapeutic Index.
J Med Chem
; 63(20): 12043-12059, 2020 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32955874
13.
New Insights for RANKL as a Proinflammatory Modulator in Modeled Inflammatory Arthritis.
Front Immunol
; 10: 97, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30804932
14.
In Silico Discovery of Plant-Origin Natural Product Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).
Front Pharmacol
; 9: 800, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30090063
15.
Current Status and Future Prospects of Small-molecule Protein-protein Interaction (PPI) Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).
Curr Top Med Chem
; 18(8): 661-673, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29875003
16.
Simultaneous inhibition of JAK and SYK kinases ameliorates chronic and destructive arthritis in mice.
Arthritis Res Ther
; 17: 356, 2015 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26653844
17.
A splicing mutation in the novel mitochondrial protein DNAJC11 causes motor neuron pathology associated with cristae disorganization, and lymphoid abnormalities in mice.
PLoS One
; 9(8): e104237, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25111180
18.
Novel genetic models of osteoporosis by overexpression of human RANKL in transgenic mice.
J Bone Miner Res
; 29(5): 1158-69, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24127173
19.
Solvent Selection for Insoluble Ligands, a Challenge for Biological Assay Development: A TNF-α/SPD304 Study.
ACS Med Chem Lett
; 4(1): 137-41, 2013 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900576
20.
Designer xanthone: an inhibitor scaffold for MDR-involved human glutathione transferase isoenzyme A1-1.
J Biomol Screen
; 18(9): 1092-102, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23749766