Detalhe da pesquisa
1.
Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis.
Cell
; 184(17): 4579-4592.e24, 2021 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34297925
2.
Incomplete transcripts dominate the Mycobacterium tuberculosis transcriptome.
Nature
; 627(8003): 424-430, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38418874
3.
Compensatory evolution in NusG improves fitness of drug-resistant M. tuberculosis.
Nature
; 628(8006): 186-194, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38509362
4.
Mutations in rv0678 Confer Low-Level Resistance to Benzothiazinone DprE1 Inhibitors in Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 66(9): e0090422, 2022 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35920665
5.
Correction: TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities.
PLoS Pathog
; 15(6): e1007846, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31163081
6.
Small RNA profiling in Mycobacterium tuberculosis identifies MrsI as necessary for an anticipatory iron sparing response.
Proc Natl Acad Sci U S A
; 115(25): 6464-6469, 2018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29871950
7.
TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities.
PLoS Pathog
; 14(3): e1006939, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29505613
8.
Cdc15 integrates Tem1 GTPase-mediated spatial signals with Polo kinase-mediated temporal cues to activate mitotic exit.
Genes Dev
; 25(18): 1943-54, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21937712
9.
DNA Replication Fidelity in the Mycobacterium tuberculosis Complex.
Adv Exp Med Biol
; 1019: 247-262, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29116639
10.
Precise genome modification in the crop species Zea mays using zinc-finger nucleases.
Nature
; 459(7245): 437-41, 2009 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-19404259
11.
Weak links: Advancing target-based drug discovery by identifying the most vulnerable targets.
Ann N Y Acad Sci
; 1535(1): 10-19, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38595325
12.
Beyond antibiotic resistance: The whiB7 transcription factor coordinates an adaptive response to alanine starvation in mycobacteria.
Cell Chem Biol
; 31(4): 669-682.e7, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38266648
13.
Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome.
Genome Res
; 20(8): 1133-42, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20508142
14.
Incomplete transcripts dominate the Mycobacterium tuberculosis transcriptome.
bioRxiv
; 2023 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36945399
15.
Beyond antibiotic resistance: the whiB7 transcription factor coordinates an adaptive response to alanine starvation in mycobacteria.
bioRxiv
; 2023 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37333137
16.
Unraveling the mechanisms of intrinsic drug resistance in Mycobacterium tuberculosis.
Front Cell Infect Microbiol
; 12: 997283, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36325467
17.
The essential M. tuberculosis Clp protease is functionally asymmetric in vivo.
Sci Adv
; 8(18): eabn7943, 2022 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35507665
18.
CRISPR Interference Reveals That All-Trans-Retinoic Acid Promotes Macrophage Control of Mycobacterium tuberculosis by Limiting Bacterial Access to Cholesterol and Propionyl Coenzyme A.
mBio
; 13(1): e0368321, 2022 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35038923
19.
Iron limitation in M. tuberculosis has broad impact on central carbon metabolism.
Commun Biol
; 5(1): 685, 2022 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35810253
20.
CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis.
Nat Microbiol
; 7(6): 766-779, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35637331