Detalhe da pesquisa
1.
Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies.
Proc Natl Acad Sci U S A
; 113(4): E459-68, 2016 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26759369
2.
Versatile strategy for controlling the specificity and activity of engineered T cells.
Proc Natl Acad Sci U S A
; 113(4): E450-8, 2016 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26759368
3.
Targeted Delivery of an Anti-inflammatory PDE4 Inhibitor to Immune Cells via an Antibody-drug Conjugate.
Mol Ther
; 24(12): 2078-2089, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27731313
4.
Development of A Chimeric Antigen Receptor Targeting C-Type Lectin-Like Molecule-1 for Human Acute Myeloid Leukemia.
Int J Mol Sci
; 18(11)2017 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29077054
5.
Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer.
Angew Chem Int Ed Engl
; 55(26): 7520-4, 2016 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27145250
6.
An anti-B cell maturation antigen bispecific antibody for multiple myeloma.
J Am Chem Soc
; 137(16): 5288-91, 2015 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25826669
7.
Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1ß production via NRF2-mediated counter-regulation of the inflammasome.
J Autoimmun
; 60: 59-73, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25975491
8.
Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation.
Exp Parasitol
; 158: 18-22, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25836375
9.
Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of interleukin-10-producing B cells and reduced plasma cell infiltration of the joints.
Immunology
; 141(3): 457-66, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24708419
10.
The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ.
Sci Rep
; 6: 37276, 2016 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27869138
11.
The parasitic worm product ES-62 targets myeloid differentiation factor 88-dependent effector mechanisms to suppress antinuclear antibody production and proteinuria in MRL/lpr mice.
Arthritis Rheumatol
; 67(4): 1023-35, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25546822
12.
ES-62 protects against collagen-induced arthritis by resetting interleukin-22 toward resolution of inflammation in the joints.
Arthritis Rheumatol
; 66(6): 1492-503, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24497523
13.
Designing anti-inflammatory drugs from parasitic worms: a synthetic small molecule analogue of the Acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritis.
J Med Chem
; 56(24): 9982-10002, 2013 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24228757