Detalhe da pesquisa
1.
Discovery of 2-aminoimidazopyridine adenosine A(2A) receptor antagonists.
Bioorg Med Chem Lett
; 20(22): 6845-9, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20869242
2.
Discovery of novel quinolinone adenosine A2B antagonists.
Bioorg Med Chem Lett
; 20(24): 7414-20, 2010 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21055932
3.
Synthesis of 2-amino-5-benzoyl-4-(2-furyl)thiazoles as adenosine A(2A) receptor antagonists.
Bioorg Med Chem Lett
; 19(2): 378-81, 2009 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19059776
4.
Synthesis and SAR studies of trisubstituted purinones as potent and selective adenosine A2A receptor antagonists.
Bioorg Med Chem Lett
; 19(5): 1399-402, 2009 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19181527
5.
Synthesis and structure-activity relationships of new disubstituted phenyl-containing 3,4-diamino-3-cyclobutene-1,2-diones as CXCR2 receptor antagonists.
Bioorg Med Chem Lett
; 18(6): 1864-8, 2008 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18304809
6.
Discovery of 2-hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5- methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123): a potent, orally bioavailable CXCR2/CXCR1 receptor antagonist.
J Med Chem
; 49(26): 7603-6, 2006 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17181143
7.
Exploring structure-activity relationships of tricyclic farnesyltransferase inhibitors using ECLiPS libraries.
Comb Chem High Throughput Screen
; 9(7): 545-58, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16925514
8.
Biological examination of melanin concentrating hormone receptor 1: multi-tasking from the hypothalamus.
Drug News Perspect
; 19(5): 273-86, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16941049
9.
Kinase inhibitors as drugs for chronic inflammatory and immunological diseases: progress and challenges.
Expert Opin Ther Targets
; 12(7): 883-903, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18554156
10.
Discovery and development of melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity.
Expert Opin Drug Discov
; 2(10): 1301-27, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23484528
11.
Discovery of tetralin ureas as potent melanin concentrating hormone 1 receptor antagonists.
Bioorg Med Chem Lett
; 17(6): 1718-21, 2007 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17251014
12.
Design, synthesis, and evaluation of tetrahydroquinoline and pyrrolidine sulfonamide carbamates as gamma-secretase inhibitors.
Bioorg Med Chem Lett
; 17(11): 3010-3, 2007 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17418571
13.
Discovery and preliminary evaluation of 5-(4-phenylbenzyl)oxazole-4-carboxamides as prostacyclin receptor antagonists.
Bioorg Med Chem Lett
; 17(5): 1211-5, 2007 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17239589
14.
Biological examination of melanin concentrating hormone receptor 1: multi-tasking from the hypothalamus.
Timely Top Med Cardiovasc Dis
; 10: E23, 2006 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17066150
15.
Guiding farnesyltransferase inhibitors from an ECLiPS library to the catalytic zinc.
Bioorg Med Chem Lett
; 16(3): 507-11, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16289818
16.
Synthesis and structure-activity relationships of 3,4-diaminocyclobut-3-ene-1,2-dione CXCR2 antagonists.
Bioorg Med Chem Lett
; 16(15): 4107-10, 2006 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16697193
17.
Discovery and SAR of 4-amino-2-biarylbutylurea MCH 1 receptor antagonists through solid-phase parallel synthesis.
Bioorg Med Chem Lett
; 15(16): 3691-5, 2005 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15953726
18.
Surfing the piperazine core of tricyclic farnesyltransferase inhibitors.
Bioorg Med Chem Lett
; 15(24): 5537-43, 2005 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16202593
19.
Discovery and SAR of biaryl piperidine MCH1 receptor antagonists through solid-phase encoded combinatorial synthesis.
Bioorg Med Chem Lett
; 15(16): 3696-700, 2005 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15978811