Detalhe da pesquisa
1.
DT-0111: a novel P2X3 receptor antagonist.
Purinergic Signal
; 19(3): 467-479, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36944825
2.
Kv1.1 Channelopathies: Pathophysiological Mechanisms and Therapeutic Approaches.
Int J Mol Sci
; 21(8)2020 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32331416
3.
Selective and brain-penetrant HCN1 inhibitors reveal links between synaptic integration, cortical function, and working memory.
Cell Chem Biol
; 31(3): 577-592.e23, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38042151
4.
Structural nucleotide analogs are potent activators/inhibitors of pancreatic ß cell KATP channels: an emerging mechanism supporting their use as antidiabetic drugs.
J Pharmacol Exp Ther
; 340(2): 266-76, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22028392
5.
A potassium channel agonist protects hearing function and promotes outer hair cell survival in a mouse model for age-related hearing loss.
Cell Death Dis
; 13(7): 595, 2022 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35817766
6.
Optogenetics and Optical Tools in Automated Patch Clamping.
Methods Mol Biol
; 2188: 311-330, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33119859
7.
Parallel All-Optical Assay to Study Use-Dependent Functioning of Voltage-Gated Ion Channels in a Miniaturized Format.
SLAS Discov
; 26(3): 460-469, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33334229
8.
Ultrasonography validation for early alteration of diaphragm echodensity and function in the mdx mouse model of Duchenne muscular dystrophy.
PLoS One
; 16(1): e0245397, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33434240
9.
Multiple pathological events in exercised dystrophic mdx mice are targeted by pentoxifylline: outcome of a large array of in vivo and ex vivo tests.
J Appl Physiol (1985)
; 106(4): 1311-24, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19131478
10.
A long-term treatment with taurine prevents cardiac dysfunction in mdx mice.
Transl Res
; 204: 82-99, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30347179
11.
Gentamicin treatment in exercised mdx mice: Identification of dystrophin-sensitive pathways and evaluation of efficacy in work-loaded dystrophic muscle.
Neurobiol Dis
; 32(2): 243-53, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18694830
12.
Proteome analysis in dystrophic mdx mouse muscle reveals a drastic alteration of key metabolic and contractile proteins after chronic exercise and the potential modulation by anti-oxidant compounds.
J Proteomics
; 170: 43-58, 2018 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28966053
13.
Data on protein abundance alteration induced by chronic exercise in mdx mice model of Duchenne muscular dystrophy and potential modulation by apocynin and taurine.
Data Brief
; 18: 555-575, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29900212
14.
Effect of a long-term treatment with metformin in dystrophic mdx mice: A reconsideration of its potential clinical interest in Duchenne muscular dystrophy.
Biochem Pharmacol
; 154: 89-103, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29684379
15.
Dual Action of Mexiletine and Its Pyrroline Derivatives as Skeletal Muscle Sodium Channel Blockers and Anti-oxidant Compounds: Toward Novel Therapeutic Potential.
Front Pharmacol
; 8: 907, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29379434
16.
Contractile efficiency of dystrophic mdx mouse muscle: in vivo and ex vivo assessment of adaptation to exercise of functional end points.
J Appl Physiol (1985)
; 122(4): 828-843, 2017 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28057817
17.
First evaluation of the potential effectiveness in muscular dystrophy of a novel chimeric compound, BN 82270, acting as calpain-inhibitor and anti-oxidant.
Neuromuscul Disord
; 16(4): 237-48, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16542837
18.
Feedback control of the ATP-sensitive K(+) current by cytosolic Ca(2+) contributes to oscillations of the membrane potential in pancreatic beta-cells.
Diabetes
; 51(2): 376-84, 2002 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-11812744
19.
SERCA3 ablation does not impair insulin secretion but suggests distinct roles of different sarcoendoplasmic reticulum Ca(2+) pumps for Ca(2+) homeostasis in pancreatic beta-cells.
Diabetes
; 51(11): 3245-53, 2002 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-12401716
20.
Editorial: From Peptide and Protein Toxins to Ion Channel Structure/Function and Drug Design.
Front Pharmacol
; 11: 548366, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33101018