Pesquisa | BVS IEC

1.

A human genome editing-based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features.

Bueno, Clara; Torres-Ruiz, Raul; Velasco-Hernandez, Talia; Molina, Oscar; Petazzi, Paolo; Martinez, Alba; Rodriguez, Virginia; Vinyoles, Meritxell; Cantilena, Sandra; Williams, Owen; Vega-Garcia, Nerea; Rodriguez-Perales, Sandra; Segovia, Jose C; Quintana-Bustamante, Oscar; Roy, Anindita; Meyer, Claus; Marschalek, Rolf; Smith, Alastair L; Milne, Thomas A; Fraga, Mario F; Tejedor, Juan Ramón; Menéndez, Pablo.

Blood ; 142(20): 1752-1756, 2023 Nov 16.

Artigo em Inglês | MEDLINE | ID: mdl-37756522

2.

Decoding human fetal liver haematopoiesis.

Popescu, Dorin-Mirel; Botting, Rachel A; Stephenson, Emily; Green, Kile; Webb, Simone; Jardine, Laura; Calderbank, Emily F; Polanski, Krzysztof; Goh, Issac; Efremova, Mirjana; Acres, Meghan; Maunder, Daniel; Vegh, Peter; Gitton, Yorick; Park, Jong-Eun; Vento-Tormo, Roser; Miao, Zhichao; Dixon, David; Rowell, Rachel; McDonald, David; Fletcher, James; Poyner, Elizabeth; Reynolds, Gary; Mather, Michael; Moldovan, Corina; Mamanova, Lira; Greig, Frankie; Young, Matthew D; Meyer, Kerstin B; Lisgo, Steven; Bacardit, Jaume; Fuller, Andrew; Millar, Ben; Innes, Barbara; Lindsay, Susan; Stubbington, Michael J T; Kowalczyk, Monika S; Li, Bo; Ashenberg, Orr; Tabaka, Marcin; Dionne, Danielle; Tickle, Timothy L; Slyper, Michal; Rozenblatt-Rosen, Orit; Filby, Andrew; Carey, Peter; Villani, Alexandra-Chloé; Roy, Anindita; Regev, Aviv; Chédotal, Alain.

Nature ; 574(7778): 365-371, 2019 10.

Artigo em Inglês | MEDLINE | ID: mdl-31597962

3.

A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes.

Harman, Joe R; Thorne, Ross; Jamilly, Max; Tapia, Marta; Crump, Nicholas T; Rice, Siobhan; Beveridge, Ryan; Morrissey, Edward; de Bruijn, Marella F T R; Roberts, Irene; Roy, Anindita; Fulga, Tudor A; Milne, Thomas A.

Genome Res ; 31(7): 1159-1173, 2021 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-34088716

4.

CD34+CD19-CD22+ B-cell progenitors may underlie phenotypic escape in patients treated with CD19-directed therapies.

Bueno, Clara; Barrera, Susana; Bataller, Alex; Ortiz-Maldonado, Valentín; Elliot, Natalina; O'Byrne, Sorcha; Wang, Guanlin; Rovira, Montse; Gutierrez-Agüera, Francisco; Trincado, Juan L; González-González, María; Morgades, Mireia; Sorigué, Marc; Bárcena, Paloma; Zanetti, Samanta Romina; Torrebadell, Montse; Vega-Garcia, Nerea; Rives, Susana; Mallo, Mar; Sole, Francesc; Mead, Adam J; Roberts, Irene; Thongjuea, Supat; Psaila, Bethan; Juan, Manel; Delgado, Julio; Urbano-Ispizúa, Alvaro; Ribera, Josep María; Orfao, Alberto; Roy, Anindita; Menendez, Pablo.

Blood ; 140(1): 38-44, 2022 07 07.

Artigo em Inglês | MEDLINE | ID: mdl-35421218

5.

The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes.

Hua, Peng; Hester, Joanna; Adigbli, George; Li, Rong; Psaila, Bethan; Roy, Anindita; Bataille, Carole J R; Wynne, Graham M; Jackson, Thomas; Milne, Thomas A; Russell, Angela J; Davies, James; Roberts, Irene; Issa, Fadi; Watt, Suzanne M.

Blood ; 136(21): 2410-2415, 2020 11 19.

Artigo em Inglês | MEDLINE | ID: mdl-32599615

6.

Scrutinizing Deleterious Nonsynonymous SNPs and Their Effect on Human POLD1 Gene.

Bappy, Md Nazmul Islam; Roy, Anindita; Rabbi, Md Gulam Rabbany; Jahan, Nusrat; Chowdhury, Fahmida Akther; Hoque, Syeda Farjana; Sajib, Emran Hossain; Khan, Parvez; Hossain, Ferdaus Mohd Altaf; Zinnah, Kazi Md Ali.

Genet Res (Camb) ; 2022: 1740768, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35620275

7.

Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs.

O'Byrne, Sorcha; Elliott, Natalina; Rice, Siobhan; Buck, Gemma; Fordham, Nicholas; Garnett, Catherine; Godfrey, Laura; Crump, Nicholas T; Wright, Gary; Inglott, Sarah; Hua, Peng; Psaila, Bethan; Povinelli, Benjamin; Knapp, David J H F; Agraz-Doblas, Antonio; Bueno, Clara; Varela, Ignacio; Bennett, Phillip; Koohy, Hashem; Watt, Suzanne M; Karadimitris, Anastasios; Mead, Adam J; Ancliff, Phillip; Vyas, Paresh; Menendez, Pablo; Milne, Thomas A; Roberts, Irene; Roy, Anindita.

Blood ; 134(13): 1059-1071, 2019 09 26.

Artigo em Inglês | MEDLINE | ID: mdl-31383639

8.

Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis.

Agraz-Doblas, Antonio; Bueno, Clara; Bashford-Rogers, Rachael; Roy, Anindita; Schneider, Pauline; Bardini, Michela; Ballerini, Paola; Cazzaniga, Gianni; Moreno, Thaidy; Revilla, Carlos; Gut, Marta; Valsecchi, Maria G; Roberts, Irene; Pieters, Rob; De Lorenzo, Paola; Varela, Ignacio; Menendez, Pablo; Stam, Ronald W.

Haematologica ; 104(6): 1176-1188, 2019 06.

Artigo em Inglês | MEDLINE | ID: mdl-30679323

9.

High resolution IgH repertoire analysis reveals fetal liver as the likely origin of life-long, innate B lymphopoiesis in humans.

Roy, Anindita; Bystry, Vojtech; Bohn, Georg; Goudevenou, Katerina; Reigl, Tomas; Papaioannou, Maria; Krejci, Adam; O'Byrne, Sorcha; Chaidos, Aristeidis; Grioni, Andrea; Darzentas, Nikos; Roberts, Irene A G; Karadimitris, Anastasios.

Clin Immunol ; 183: 8-16, 2017 10.

Artigo em Inglês | MEDLINE | ID: mdl-28645875

10.

A "gut feeling" about precursor B-ALL.

Roy, Anindita.

Blood ; 136(18): 1995-1996, 2020 10 29.

Artigo em Inglês | MEDLINE | ID: mdl-33119762

11.

Stem and progenitor cell dysfunction in human trisomies.

Liu, Binbin; Filippi, Sarah; Roy, Anindita; Roberts, Irene.

EMBO Rep ; 16(1): 44-62, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25520324

12.

Single-cell analysis of bone marrow-derived CD34+ cells from children with sickle cell disease and thalassemia.

Hua, Peng; Roy, Noemi; de la Fuente, Josu; Wang, Guanlin; Thongjuea, Supat; Clark, Kevin; Roy, Anindita; Psaila, Bethan; Ashley, Neil; Harrington, Yvonne; Nerlov, Claus; Watt, Suzanne M; Roberts, Irene; Davies, James O J.

Blood ; 134(23): 2111-2115, 2019 12 05.

Artigo em Inglês | MEDLINE | ID: mdl-31697810

13.

Metal Bromide Controlled Interfacial Aromatization Reaction for Shape-Selective Synthesis of Palladium Nanostructures with Efficient Catalytic Performances.

Dutta, Soumen; Ray, Chaiti; Roy, Anindita; Sahoo, Ramkrishna; Pal, Tarasankar.

Chemistry ; 22(29): 10017-27, 2016 Jul 11.

Artigo em Inglês | MEDLINE | ID: mdl-27294801

14.

GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia.

Roberts, Irene; Alford, Kate; Hall, Georgina; Juban, Gaetan; Richmond, Helen; Norton, Alice; Vallance, Grant; Perkins, Kelly; Marchi, Emanuele; McGowan, Simon; Roy, Anindita; Cowan, Gillian; Anthony, Mark; Gupta, Amit; Ho, John; Uthaya, Sabita; Curley, Anna; Rasiah, Shree Vishna; Watts, Timothy; Nicholl, Richard; Bedford-Russell, Alison; Blumberg, Raoul; Thomas, Angela; Gibson, Brenda; Halsey, Chris; Lee, Pek-Wan; Godambe, Sunit; Sweeney, Connor; Bhatnagar, Neha; Goriely, Anne; Campbell, Peter; Vyas, Paresh.

Blood ; 122(24): 3908-17, 2013 Dec 05.

Artigo em Inglês | MEDLINE | ID: mdl-24021668

15.

Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21.

Roy, Anindita; Cowan, Gillian; Mead, Adam J; Filippi, Sarah; Bohn, Georg; Chaidos, Aristeidis; Tunstall, Oliver; Chan, Jerry K Y; Choolani, Mahesh; Bennett, Phillip; Kumar, Sailesh; Atkinson, Deborah; Wyatt-Ashmead, Josephine; Hu, Ming; Stumpf, Michael P H; Goudevenou, Katerina; O'Connor, David; Chou, Stella T; Weiss, Mitchell J; Karadimitris, Anastasios; Jacobsen, Sten Eirik; Vyas, Paresh; Roberts, Irene.

Proc Natl Acad Sci U S A ; 109(43): 17579-84, 2012 Oct 23.

Artigo em Inglês | MEDLINE | ID: mdl-23045701

16.

Morphology controlled synthesis of SnS2 nanomaterial for promoting photocatalytic reduction of aqueous Cr(VI) under visible light.

Mondal, Chanchal; Ganguly, Mainak; Pal, Jaya; Roy, Anindita; Jana, Jayasmita; Pal, Tarasankar.

Langmuir ; 30(14): 4157-64, 2014 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-24649847

17.

Aberrant stem cell and developmental programs in pediatric leukemia.

Ling, Rebecca E; Cross, Joe W; Roy, Anindita.

Front Cell Dev Biol ; 12: 1372899, 2024.

Artigo em Inglês | MEDLINE | ID: mdl-38601080

18.

The impact of trisomy 21 on foetal haematopoiesis.

Roberts, Irene; O'Connor, David; Roy, Anindita; Cowan, Gillian; Vyas, Paresh.

Blood Cells Mol Dis ; 51(4): 277-81, 2013 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-23932236

19.

Subtractive proteomics analysis to uncover the potent drug targets for distinctive drug design of Candidaauris.

Bappy, Md Nazmul Islam; Robin, Tanjin Barketullah; Prome, Anindita Ash; Patil, Rajesh B; Moin, Abu Tayab; Akter, Rupali; Laskar, Fayeza Sadia; Roy, Anindita; Akter, Hafsa; Zinnah, Kazi Md Ali.

Heliyon ; 9(6): e17026, 2023 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-37484251

20.

A review on computational studies and bioinformatics analysis of potential drugs against monkeypox virus.

Hossain, Ferdaus Mohd Altaf; Bappy, Md Nazmul Islam; Robin, Tanjin Barketullah; Ahmad, Iqrar; Patel, Harun; Jahan, Nusrat; Rabbi, Md Gulam Rabbany; Roy, Anindita; Chowdhury, Wasima; Ahmed, Nadim; Prome, Anindita Ash; Rani, Nurul Amin; Khan, Parvez; Zinnah, Kazi Md Ali.

J Biomol Struct Dyn ; : 1-17, 2023 Jul 04.

Artigo em Inglês | MEDLINE | ID: mdl-37403283

BVS IEC

Instituto Evandro Chagas

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