Detalhe da pesquisa
1.
Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida.
Nucleic Acids Res
; 49(16): 9560-9573, 2021 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34417608
2.
Cryo-EM structure of the highly atypical cytoplasmic ribosome of Euglena gracilis.
Nucleic Acids Res
; 48(20): 11750-11761, 2020 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33091122
3.
Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus.
Nucleic Acids Res
; 45(17): 10284-10292, 2017 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28973455
4.
Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
Proc Natl Acad Sci U S A
; 113(44): E6796-E6805, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27791159
5.
Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc Natl Acad Sci U S A
; 112(43): E5805-14, 2015 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26464510
6.
Structural basis for selective targeting of leishmanial ribosomes: aminoglycoside derivatives as promising therapeutics.
Nucleic Acids Res
; 43(17): 8601-13, 2015 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26264664
7.
Structure of the bovine COPI δ subunit µ homology domain at 2.15 Å resolution.
Acta Crystallogr D Biol Crystallogr
; 71(Pt 6): 1328-34, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26057672
8.
Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions.
Nucleic Acids Res
; 41(18): 8748-59, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23863845
9.
Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
Proc Natl Acad Sci U S A
; 108(7): 2717-22, 2011 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21282615
10.
Allostery through DNA drives phenotype switching.
Nat Commun
; 12(1): 2967, 2021 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34016970
11.
Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ).
Nat Commun
; 12(1): 7057, 2021 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34862374
12.
New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins.
Structure
; 26(9): 1237-1250.e6, 2018 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30057026
13.
Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.
Nat Commun
; 8(1): 1589, 2017 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29150609
14.
The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
Structure
; 25(8): 1233-1241.e3, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28689968
15.
A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
Sci Rep
; 6: 39004, 2016 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27958389
16.
2.8-Å Cryo-EM Structure of the Large Ribosomal Subunit from the Eukaryotic Parasite Leishmania.
Cell Rep
; 16(2): 288-294, 2016 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27373148
17.
Ribosomal Antibiotics: Contemporary Challenges.
Antibiotics (Basel)
; 5(3)2016 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27367739
18.
Does PCNA diffusion on DNA follow a rotation-coupled translation mechanism?
Nat Commun
; 11(1): 5000, 2020 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33020481
19.
Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody.
Structure
; 23(1): 104-115, 2015 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25482542
20.
The first fully characterized neutral and cationic rhodium(I)-complexes containing DMSO as the only dative ligand; S-, O- and bridging S,O-bidentate binding modes.
Chem Commun (Camb)
; (7): 710-1, 2002 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-12119685