Detalhe da pesquisa
1.
Phase I Trial Characterizing the Pharmacokinetic Profile of N-803, a Chimeric IL-15 Superagonist, in Healthy Volunteers.
J Immunol
; 208(6): 1362-1370, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35228263
2.
Ex vivo blockade of PI3K gamma or delta signaling enhances the antitumor potency of adoptively transferred CD8+ T cells.
Eur J Immunol
; 50(9): 1386-1399, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32383488
3.
Thioredoxin-1 improves the immunometabolic phenotype of antitumor T cells.
J Biol Chem
; 294(23): 9198-9212, 2019 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30971427
4.
PD-1-Targeted Immunotherapy: The Ligand Matters.
J Immunol
; 211(7): 1065-1066, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37722094
5.
ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial.
Lancet Oncol
; 19(5): 694-704, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29628312
6.
The clinical implications of immunogenomics in colorectal cancer: A path for precision medicine.
Cancer
; 124(8): 1650-1659, 2018 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29315503
7.
A Novel Fusion of ALT-803 (Interleukin (IL)-15 Superagonist) with an Antibody Demonstrates Antigen-specific Antitumor Responses.
J Biol Chem
; 291(46): 23869-23881, 2016 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27650494
8.
Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis.
Cancer Immunol Immunother
; 66(6): 737-751, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28280853
9.
The inducible costimulator augments Tc17 cell responses to self and tumor tissue.
J Immunol
; 194(4): 1737-47, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25576595
10.
Exploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinic.
Cancer Immunol Immunother
; 65(3): 247-59, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26825102
11.
Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8(+) T cells.
Cancer Immunol Immunother
; 64(5): 539-49, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25676709
12.
Soluble IL-15/IL-15Rα complexes in human serum.
Blood
; 120(1): 1-2, 2012 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22767572
13.
Corrigendum: Brief research report: impact of vaccination on antibody responses and mortality from severe COVID-19.
Front Immunol
; 15: 1384209, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38482012
14.
Brief research report: impact of vaccination on antibody responses and mortality from severe COVID-19.
Front Immunol
; 15: 1325243, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38390335
15.
Translational and oncologic significance of tertiary lymphoid structures in pancreatic adenocarcinoma.
Front Immunol
; 15: 1324093, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38361928
16.
mRNA vaccines against SARS-CoV-2 induce divergent antigen-specific T-cell responses in patients with lung cancer.
J Immunother Cancer
; 12(1)2024 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38177076
17.
Post-infusion PD-1+CD8+CAR-T cells identify patients responsive to CD19-CAR-T therapy in non-Hodgkin's lymphoma.
Blood Adv
; 2024 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38607381
18.
Antiviral CD4+ memory T cells are IL-15 dependent.
J Exp Med
; 204(4): 951-61, 2007 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-17420265
19.
An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2.
J Exp Med
; 204(8): 1787-801, 2007 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-17664294
20.
Inducible Enhancement of T Cell Function and Anti-tumor Activity after Adoptive Transfer.
Mol Ther
; 25(9): 1995-1996, 2017 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28830671