Detalhe da pesquisa
1.
Up and Down γ-Synuclein Transcription in Dopamine Neurons Translates into Changes in Dopamine Neurotransmission and Behavioral Performance in Mice.
Int J Mol Sci
; 23(3)2022 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35163729
2.
mTOR Knockdown in the Infralimbic Cortex Evokes A Depressive-like State in Mouse.
Int J Mol Sci
; 22(16)2021 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34445375
3.
Intracerebral Administration of a Ligand-ASO Conjugate Selectively Reduces α-Synuclein Accumulation in Monoamine Neurons of Double Mutant Human A30P*A53T*α-Synuclein Transgenic Mice.
Int J Mol Sci
; 22(6)2021 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33805843
4.
Regionally selective knockdown of astroglial glutamate transporters in infralimbic cortex induces a depressive phenotype in mice.
Glia
; 67(6): 1122-1137, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30635928
5.
Overexpression of TFEB Drives a Pleiotropic Neurotrophic Effect and Prevents Parkinson's Disease-Related Neurodegeneration.
Mol Ther
; 26(6): 1552-1567, 2018 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29628303
6.
Selective α-Synuclein Knockdown in Monoamine Neurons by Intranasal Oligonucleotide Delivery: Potential Therapy for Parkinson's Disease.
Mol Ther
; 26(2): 550-567, 2018 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29273501
7.
ER stress in mouse serotonin neurons triggers a depressive phenotype alleviated by ketamine targeting eIF2α signaling.
iScience
; 27(5): 109787, 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38711453
8.
Human α-synuclein overexpression in mouse serotonin neurons triggers a depressive-like phenotype. Rescue by oligonucleotide therapy.
Transl Psychiatry
; 12(1): 79, 2022 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35210396
9.
Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys.
EBioMedicine
; 59: 102944, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32810825
10.
Selective Knockdown of TASK3 Potassium Channel in Monoamine Neurons: a New Therapeutic Approach for Depression.
Mol Neurobiol
; 56(4): 3038-3052, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30088175
11.
Corrigendum to "Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys" [EBioMedicine 2020; 59:102944].
EBioMedicine
; 74: 103731, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34852293