Detalhe da pesquisa
1.
UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Mol Cell
; 83(15): 2753-2767.e10, 2023 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37478846
2.
Induced protein degradation for therapeutics: past, present, and future.
J Clin Invest
; 134(1)2024 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38165043
3.
PitViper: a software for comparative meta-analysis and annotation of functional screening data.
NAR Genom Bioinform
; 6(2): lqae059, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38800827
4.
Mediator kinase inhibition impedes transcriptional plasticity and prevents resistance to ERK/MAPK-targeted therapy in KRAS-mutant cancers.
NPJ Precis Oncol
; 8(1): 124, 2024 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38822082
5.
Targeting a lineage-specific PI3KÉ£-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule.
Nat Cancer
; 2024 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38816660
6.
Exploration of the Tunability of BRD4 Degradation by DCAF16 Trans-labelling Covalent Glues.
bioRxiv
; 2023 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37873358
7.
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.
Cell Metab
; 35(5): 887-905.e11, 2023 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37075753
8.
Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited.
Nat Metab
; 4(6): 711-723, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35739397
9.
P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia.
Nat Cancer
; 3(7): 837-851, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35668193
10.
Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer.
Nat Genet
; 52(4): 408-417, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32203462
11.
The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies.
Cancer Discov
; 10(12): 1894-1911, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32826232
12.
Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity.
Cell Metab
; 29(5): 1217-1231.e7, 2019 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30773463