Detalhe da pesquisa
1.
Concomitant targeting of FLT3 and BTK overcomes FLT3 inhibitor resistance in acute myeloid leukemia through the inhibition of autophagy.
Haematologica
; 108(6): 1500-1514, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36226489
2.
Targeting MCL-1 dysregulates cell metabolism and leukemia-stroma interactions and resensitizes acute myeloid leukemia to BCL-2 inhibition.
Haematologica
; 107(1): 58-76, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33353284
3.
AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill FLT3-ITD acute myeloid leukemia.
Haematologica
; 107(6): 1311-1322, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34732043
4.
Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models.
Haematologica
; 105(3): 697-707, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31123034
5.
Role of MSC-derived galectin 3 in the AML microenvironment.
Biochim Biophys Acta Mol Cell Res
; 1865(7): 959-969, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29655803
6.
Atg7 suppression enhances chemotherapeutic agent sensitivity and overcomes stroma-mediated chemoresistance in acute myeloid leukemia.
Blood
; 128(9): 1260-9, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27268264
7.
Combinatorial targeting of XPO1 and FLT3 exerts synergistic anti-leukemia effects through induction of differentiation and apoptosis in FLT3-mutated acute myeloid leukemias: from concept to clinical trial.
Haematologica
; 103(10): 1642-1653, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29773601
8.
Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival.
Haematologica
; 103(5): 810-821, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29545342
9.
Combination of galectin inhibitor GCS-100 and BH3 mimetics eliminates both p53 wild type and p53 null AML cells.
Biochim Biophys Acta
; 1863(4): 562-71, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26704388
10.
Inhibition of Mcl-1 with the pan-Bcl-2 family inhibitor (-)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia.
Blood
; 126(3): 363-72, 2015 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26045609
11.
Anexelekto/MER tyrosine kinase inhibitor ONO-7475 arrests growth and kills FMS-like tyrosine kinase 3-internal tandem duplication mutant acute myeloid leukemia cells by diverse mechanisms.
Haematologica
; 102(12): 2048-2057, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28912176
12.
The protein phosphatase 2A regulatory subunit B55α is a modulator of signaling and microRNA expression in acute myeloid leukemia cells.
Biochim Biophys Acta
; 1843(9): 1969-77, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24858343
13.
Prognostic impact and targeting of CRM1 in acute myeloid leukemia.
Blood
; 121(20): 4166-74, 2013 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23564911
14.
Connective tissue growth factor regulates adipocyte differentiation of mesenchymal stromal cells and facilitates leukemia bone marrow engraftment.
Blood
; 122(3): 357-66, 2013 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23741006
15.
Induction of p53-mediated transcription and apoptosis by exportin-1 (XPO1) inhibition in mantle cell lymphoma.
Cancer Sci
; 105(7): 795-801, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24766216
16.
Apoptosis repressor with caspase recruitment domain modulates second mitochondrial-derived activator of caspases mimetic-induced cell death through BIRC2/MAP3K14 signalling in acute myeloid leukaemia.
Br J Haematol
; 167(3): 376-84, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25079338
17.
Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia.
Nat Med
; 13(6): 730-5, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17515897
18.
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.
Cancer Cell
; 10(5): 375-88, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17097560
19.
Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia.
Leukemia
; 38(4): 729-740, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38148395
20.
Chromatin Profiles Are Prognostic of Clinical Response to Bortezomib-Containing Chemotherapy in Pediatric Acute Myeloid Leukemia: Results from the COG AAML1031 Trial.
Cancers (Basel)
; 16(8)2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38672531