Detalhe da pesquisa
1.
Adult alcohol drinking and emotional tone are mediated by neutral sphingomyelinase during development in males.
Cereb Cortex
; 33(3): 844-864, 2023 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35296883
2.
Neutral ceramidase-active site inhibitor chemotypes and binding modes.
Bioorg Chem
; 139: 106747, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37531819
3.
Structural insights into adiponectin receptors suggest ceramidase activity.
Nature
; 544(7648): 120-123, 2017 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28329765
4.
Subunit composition of the mammalian serine-palmitoyltransferase defines the spectrum of straight and methyl-branched long-chain bases.
Proc Natl Acad Sci U S A
; 117(27): 15591-15598, 2020 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32576697
5.
Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects.
Mol Psychiatry
; 26(12): 7403-7416, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34584229
6.
Metabolomics and Lipidomics Screening Reveal Reprogrammed Signaling Pathways toward Cancer Development in Non-Alcoholic Steatohepatitis.
Int J Mol Sci
; 24(1)2022 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36613653
7.
Development of Novel 1,3-Disubstituted-2-Thiohydantoin Analogues with Potent Anti-Inflammatory Activity; In Vitro and In Silico Assessments.
Molecules
; 27(19)2022 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36234810
8.
Novel 1,3-Thiazole Analogues with Potent Activity against Breast Cancer: A Design, Synthesis, In Vitro, and In Silico Study.
Molecules
; 27(15)2022 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35956848
9.
Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases.
Angew Chem Int Ed Engl
; 61(2): e202109967, 2022 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34668624
10.
Cyanobacteria-From the Oceans to the Potential Biotechnological and Biomedical Applications.
Mar Drugs
; 19(5)2021 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33923369
11.
Stereoselective Synthesis of Novel Sphingoid Bases Utilized for Exploring the Secrets of Sphinx.
Int J Mol Sci
; 22(15)2021 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34360937
12.
Liposomal FRET Assay Identifies Potent Drug-Like Inhibitors of the Ceramide Transport Protein (CERT).
Chemistry
; 26(70): 16616-16621, 2020 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33047409
13.
Novel Papaverine Metal Complexes with Potential Anticancer Activities.
Molecules
; 25(22)2020 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33233775
14.
Resolving Sphingolipid Isomers Using Cryogenic Infrared Spectroscopy.
Angew Chem Int Ed Engl
; 59(32): 13638-13642, 2020 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32291895
15.
Tsc3 regulates SPT amino acid choice in Saccharomyces cerevisiae by promoting alanine in the sphingolipid pathway.
J Lipid Res
; 59(11): 2126-2139, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30154231
16.
Differential-Mobility Spectrometry of 1-Deoxysphingosine Isomers: New Insights into the Gas Phase Structures of Ionized Lipids.
Anal Chem
; 90(8): 5343-5351, 2018 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29608293
17.
The cellular ceramide transport protein CERT promotes Chlamydia psittaci infection and controls bacterial sphingolipid uptake.
Cell Microbiol
; 19(10)2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28544656
18.
Synthesis and characterization of some atypical sphingoid bases.
Bioorg Med Chem
; 26(14): 4047-4057, 2018 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29960730
19.
Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway.
J Lipid Res
; 58(1): 60-71, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27872144
20.
Elemental labelling and mass spectrometry for the specific detection of sulfenic acid groups in model peptides: a proof of concept.
Anal Bioanal Chem
; 409(8): 2015-2027, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28097376