Detalhe da pesquisa
1.
Roxadustat (FG-4592): Correction of Anemia in Incident Dialysis Patients.
J Am Soc Nephrol
; 27(4): 1225-33, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26494833
2.
Roxadustat (FG-4592) Versus Epoetin Alfa for Anemia in Patients Receiving Maintenance Hemodialysis: A Phase 2, Randomized, 6- to 19-Week, Open-Label, Active-Comparator, Dose-Ranging, Safety and Exploratory Efficacy Study.
Am J Kidney Dis
; 67(6): 912-24, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26846333
3.
Tirasemtiv amplifies skeletal muscle response to nerve activation in humans.
Muscle Nerve
; 50(6): 925-31, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24634285
4.
Dose-dependent augmentation of cardiac systolic function with the selective cardiac myosin activator, omecamtiv mecarbil: a first-in-man study.
Lancet
; 378(9792): 667-75, 2011 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21856480
5.
The effects of the cardiac myosin activator, omecamtiv mecarbil, on cardiac function in systolic heart failure: a double-blind, placebo-controlled, crossover, dose-ranging phase 2 trial.
Lancet
; 378(9792): 676-83, 2011 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21856481
6.
Phase I dose-escalation and pharmacokinetic study of ispinesib, a kinesin spindle protein inhibitor, administered on days 1 and 15 of a 28-day schedule in patients with no prior treatment for advanced breast cancer.
Anticancer Drugs
; 23(3): 335-41, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22123335
7.
Safety, tolerability and pharmacodynamics of a skeletal muscle activator in amyotrophic lateral sclerosis.
Amyotroph Lateral Scler
; 13(5): 430-8, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22591195
8.
Retraction notice to "Pooled Analysis of Roxadustat for Anemia in Patients With Kidney Failure Incident to Dialysis." Kidney Int Rep. 2021;6:613-623.
Kidney Int Rep
; 7(3): 665, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35257087
9.
Efficacy and Cardiovascular Safety of Roxadustat for Treatment of Anemia in Patients with Non-Dialysis-Dependent CKD: Pooled Results of Three Randomized Clinical Trials.
Clin J Am Soc Nephrol
; 16(8): 1190-1200, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34362786
10.
Pooled Analysis of Roxadustat for Anemia in Patients With Kidney Failure Incident to Dialysis.
Kidney Int Rep
; 6(3): 613-623, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33732976
11.
Roxadustat for CKD-related Anemia in Non-dialysis Patients.
Kidney Int Rep
; 6(3): 624-635, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33732977
12.
A Randomized Trial of Roxadustat in Anemia of Kidney Failure: SIERRAS Study.
Kidney Int Rep
; 6(7): 1829-1839, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34307977
13.
A double-blind, randomized, placebo-controlled trial of escitalopram in the treatment of pediatric depression.
J Am Acad Child Adolesc Psychiatry
; 45(3): 280-288, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16540812
14.
Oral Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat (FG-4592) for the Treatment of Anemia in Patients with CKD.
Clin J Am Soc Nephrol
; 11(6): 982-991, 2016 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27094610
15.
The addition of granulocyte-colony stimulating factor shifts the dose limiting toxicity and markedly increases the maximum tolerated dose and activity of the kinesin spindle protein inhibitor SB-743921 in patients with relapsed or refractory lymphoma: results of an international, multicenter phase I/II study.
Leuk Lymphoma
; 56(9): 2585-91, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25665464
16.
Safety and tolerability of omecamtiv mecarbil during exercise in patients with ischemic cardiomyopathy and angina.
JACC Heart Fail
; 3(1): 22-29, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25453536
17.
Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases.
Nat Med
; 18(3): 452-5, 2012 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22344294
18.
Escitalopram maintenance treatment for prevention of recurrent depression: a randomized, placebo-controlled trial.
J Clin Psychiatry
; 67(11): 1767-75, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17196058
19.
Determining the earliest time within 30 minutes to erectogenic effect after tadalafil 10 and 20 mg: a multicenter, randomized, double-blind, placebo-controlled, at-home study.
J Sex Med
; 1(2): 193-200, 2004 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16422974
20.
Tadalafil has no detrimental effect on human spermatogenesis or reproductive hormones.
J Urol
; 170(3): 887-91, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12913723