Pesquisa | BVS IEC

1.

Regulated cell death: signaling and mechanisms.

Ashkenazi, Avi; Salvesen, Guy.

Annu Rev Cell Dev Biol ; 30: 337-56, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-25150011

2.

Oxidation of caspase-8 by hypothiocyanous acid enables TNF-mediated necroptosis.

Bozonet, Stephanie M; Magon, Nicholas J; Schwartfeger, Abigail J; Konigstorfer, Andreas; Heath, Sarah G; Vissers, Margreet C M; Morris, Vanessa K; Göbl, Christoph; Murphy, James M; Salvesen, Guy S; Hampton, Mark B.

J Biol Chem ; 299(6): 104792, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-37150321

3.

The CULt of caspase-8 ubiquitination.

Békés, Miklós; Salvesen, Guy S.

Cell ; 137(4): 604-6, 2009 May 15.

Artigo em Inglês | MEDLINE | ID: mdl-19450509

4.

Evolution of Caspases and the Invention of Pyroptosis.

Bibo-Verdugo, Betsaida; Salvesen, Guy.

Int J Mol Sci ; 25(10)2024 May 12.

Artigo em Inglês | MEDLINE | ID: mdl-38791309

5.

Resurrection of an ancient inflammatory locus reveals switch to caspase-1 specificity on a caspase-4 scaffold.

Bibo-Verdugo, Betsaida; Joglekar, Isha; Karadi Giridhar, Mithun N; Ramirez, Monica L; Snipas, Scott J; Clark, A Clay; Poreba, Marcin; Salvesen, Guy S.

J Biol Chem ; 298(6): 101931, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35427646

6.

Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases.

Minina, Elena A; Staal, Jens; Alvarez, Vanina E; Berges, John A; Berman-Frank, Ilana; Beyaert, Rudi; Bidle, Kay D; Bornancin, Frédéric; Casanova, Magali; Cazzulo, Juan J; Choi, Chang Jae; Coll, Nuria S; Dixit, Vishva M; Dolinar, Marko; Fasel, Nicolas; Funk, Christiane; Gallois, Patrick; Gevaert, Kris; Gutierrez-Beltran, Emilio; Hailfinger, Stephan; Klemencic, Marina; Koonin, Eugene V; Krappmann, Daniel; Linusson, Anna; Machado, Maurício F M; Madeo, Frank; Megeney, Lynn A; Moschou, Panagiotis N; Mottram, Jeremy C; Nyström, Thomas; Osiewacz, Heinz D; Overall, Christopher M; Pandey, Kailash C; Ruland, Jürgen; Salvesen, Guy S; Shi, Yigong; Smertenko, Andrei; Stael, Simon; Ståhlberg, Jerry; Suárez, María Fernanda; Thome, Margot; Tuominen, Hannele; Van Breusegem, Frank; van der Hoorn, Renier A L; Vardi, Assaf; Zhivotovsky, Boris; Lam, Eric; Bozhkov, Peter V.

Mol Cell ; 77(5): 927-929, 2020 03 05.

Artigo em Inglês | MEDLINE | ID: mdl-32142688

7.

Gain of function of a metalloproteinase associated with multiple myeloma, bicuspid aortic valve, and Von Hippel-Lindau syndrome.

Snipas, Scott J; Jappelli, Roberto; Torkamani, Ali; Paternostro, Giovanni; Salvesen, Guy S.

Biochem J ; 479(14): 1533-1542, 2022 07 29.

Artigo em Inglês | MEDLINE | ID: mdl-35789254

8.

Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy.

Tom, Irene; Pham, Victoria C; Katschke, Kenneth J; Li, Wei; Liang, Wei-Ching; Gutierrez, Johnny; Ah Young, Andrew; Figueroa, Isabel; Eshghi, Shadi Toghi; Lee, ChingWei V; Kanodia, Jitendra; Snipas, Scott J; Salvesen, Guy S; Lai, Phillip; Honigberg, Lee; van Lookeren Campagne, Menno; Kirchhofer, Daniel; Baruch, Amos; Lill, Jennie R.

Proc Natl Acad Sci U S A ; 117(18): 9952-9963, 2020 05 05.

Artigo em Inglês | MEDLINE | ID: mdl-32345717

9.

Protease Specificity: Towards In Vivo Imaging Applications and Biomarker Discovery.

Vizovisek, Matej; Vidmar, Robert; Drag, Marcin; Fonovic, Marko; Salvesen, Guy S; Turk, Boris.

Trends Biochem Sci ; 43(10): 829-844, 2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-30097385

10.

Evaluation of the effects of phosphorylation of synthetic peptide substrates on their cleavage by caspase-3 and -7.

Maluch, Izabela; Grzymska, Justyna; Snipas, Scott J; Salvesen, Guy S; Drag, Marcin.

Biochem J ; 478(12): 2233-2245, 2021 06 25.

Artigo em Inglês | MEDLINE | ID: mdl-34037204

11.

Extended subsite profiling of the pyroptosis effector protein gasdermin D reveals a region recognized by inflammatory caspase-11.

Bibo-Verdugo, Betsaida; Snipas, Scott J; Kolt, Sonia; Poreba, Marcin; Salvesen, Guy S.

J Biol Chem ; 295(32): 11292-11302, 2020 08 07.

Artigo em Inglês | MEDLINE | ID: mdl-32554464

12.

Selective inhibition of matrix metalloproteinase 10 (MMP10) with a single-domain antibody.

Razai, Amir S; Eckelman, Brendan P; Salvesen, Guy S.

J Biol Chem ; 295(8): 2464-2472, 2020 02 21.

Artigo em Inglês | MEDLINE | ID: mdl-31953328

13.

NETosis occurs independently of neutrophil serine proteases.

Kasperkiewicz, Paulina; Hempel, Anne; Janiszewski, Tomasz; Kolt, Sonia; Snipas, Scott J; Drag, Marcin; Salvesen, Guy S.

J Biol Chem ; 295(51): 17624-17631, 2020 12 18.

Artigo em Inglês | MEDLINE | ID: mdl-33454002

14.

Noninvasive optical detection of granzyme B from natural killer cells with enzyme-activated fluorogenic probes.

Janiszewski, Tomasz; Kolt, Sonia; Kaiserman, Dion; Snipas, Scott J; Li, Shuang; Kulbacka, Julita; Saczko, Jolanta; Bovenschen, Niels; Salvesen, Guy; Drag, Marcin; Bird, Phillip I; Kasperkiewicz, Paulina.

J Biol Chem ; 295(28): 9567-9582, 2020 07 10.

Artigo em Inglês | MEDLINE | ID: mdl-32439802

15.

The Pyroptotic Cell Death Effector Gasdermin D Is Activated by Gout-Associated Uric Acid Crystals but Is Dispensable for Cell Death and IL-1ß Release.

Rashidi, Maryam; Simpson, Daniel S; Hempel, Anne; Frank, Daniel; Petrie, Emma; Vince, Angelina; Feltham, Rebecca; Murphy, Jane; Chatfield, Simon M; Salvesen, Guy S; Murphy, James M; Wicks, Ian P; Vince, James E.

J Immunol ; 203(3): 736-748, 2019 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-31209100

16.

Snapshot: caspases.

Salvesen, Guy S; Ashkenazi, Avi.

Cell ; 147(2): 476-476.e1, 2011 Oct 14.

Artigo em Inglês | MEDLINE | ID: mdl-22000022

17.

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.

Kayagaki, Nobuhiko; Stowe, Irma B; Lee, Bettina L; O'Rourke, Karen; Anderson, Keith; Warming, Søren; Cuellar, Trinna; Haley, Benjamin; Roose-Girma, Merone; Phung, Qui T; Liu, Peter S; Lill, Jennie R; Li, Hong; Wu, Jiansheng; Kummerfeld, Sarah; Zhang, Juan; Lee, Wyne P; Snipas, Scott J; Salvesen, Guy S; Morris, Lucy X; Fitzgerald, Linda; Zhang, Yafei; Bertram, Edward M; Goodnow, Christopher C; Dixit, Vishva M.

Nature ; 526(7575): 666-71, 2015 Oct 29.

Artigo em Inglês | MEDLINE | ID: mdl-26375259

18.

A primer on caspase mechanisms.

Ramirez, Monica L Gonzalez; Salvesen, Guy S.

Semin Cell Dev Biol ; 82: 79-85, 2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-29329946

19.

Multiplexed Probing of Proteolytic Enzymes Using Mass Cytometry-Compatible Activity-Based Probes.

Poreba, Marcin; Groborz, Katarzyna M; Rut, Wioletta; Pore, Milind; Snipas, Scott J; Vizovisek, Matej; Turk, Boris; Kuhn, Peter; Drag, Marcin; Salvesen, Guy S.

J Am Chem Soc ; 142(39): 16704-16715, 2020 09 30.

Artigo em Inglês | MEDLINE | ID: mdl-32870676

20.

Design, synthesis, and in vitro evaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors.

Corrigan, Thomas S; Lotti Diaz, Leilani M; Border, Sarah E; Ratigan, Steven C; Kasper, Kayla Q; Sojka, Daniel; Fajtova, Pavla; Caffrey, Conor R; Salvesen, Guy S; McElroy, Craig A; Hadad, Christopher M; Dogan Ekici, Özlem.

J Enzyme Inhib Med Chem ; 35(1): 1387-1402, 2020 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-32633155

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Instituto Evandro Chagas

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