Detalhe da pesquisa
1.
Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer's disease.
Proc Natl Acad Sci U S A
; 118(3)2021 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33446504
2.
TREM2-activating antibodies abrogate the negative pleiotropic effects of the Alzheimer's disease variant Trem2R47H on murine myeloid cell function.
J Biol Chem
; 293(32): 12620-12633, 2018 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29599291
3.
Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2.
J Biol Chem
; 293(32): 12634-12646, 2018 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29794134
4.
Beltless translocation domain of botulinum neurotoxin A embodies a minimum ion-conductive channel.
J Biol Chem
; 287(3): 1657-61, 2012 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22158863
5.
Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature
; 447(7143): 453-7, 2007 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-17468747
6.
Uncompetitive, adduct-forming SARM1 inhibitors are neuroprotective in preclinical models of nerve injury and disease.
Neuron
; 110(22): 3711-3726.e16, 2022 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36087583
7.
Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure.
Nature
; 437(7056): 266-9, 2005 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-16148936
8.
SARM1 signaling mechanisms in the injured nervous system.
Curr Opin Neurobiol
; 69: 247-255, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34175654
9.
Structural and Mechanistic Regulation of the Pro-degenerative NAD Hydrolase SARM1.
Cell Rep
; 32(5): 107999, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32755591
10.
Ribonuclease A suggests how proteins self-chaperone against amyloid fiber formation.
Protein Sci
; 21(1): 26-37, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22095666
11.
The structural biology of protein aggregation diseases: Fundamental questions and some answers.
Acc Chem Res
; 39(9): 568-75, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16981672