Detalhe da pesquisa
1.
Post-stroke administration of H2 relaxin reduces functional deficits, neuronal apoptosis and immune cell infiltration into the mouse brain.
Pharmacol Res
; 187: 106611, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36526079
2.
Sulforaphane prevents and reverses allergic airways disease in mice via anti-inflammatory, antioxidant, and epigenetic mechanisms.
Cell Mol Life Sci
; 79(11): 579, 2022 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36319916
3.
A Lipidated Single-B-Chain Derivative of Relaxin Exhibits Improved In Vitro Serum Stability without Altering Activity.
Int J Mol Sci
; 24(7)2023 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37047588
4.
Targeting angiopoietin-2 as a novel treatment option for kidney fibrosis.
Kidney Int
; 102(4): 691-694, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36150760
5.
Assessment of renal fibrosis and anti-fibrotic agents using a novel diagnostic and stain-free second-harmonic generation platform.
FASEB J
; 35(5): e21595, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33908676
6.
Enhancing the Therapeutic Potential of Mesenchymal Stromal Cell-Based Therapies with an Anti-Fibrotic Agent for the Treatment of Chronic Kidney Disease.
Int J Mol Sci
; 23(11)2022 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35682717
7.
Relaxin Inhibits the Cardiac Myofibroblast NLRP3 Inflammasome as Part of Its Anti-Fibrotic Actions via the Angiotensin Type 2 and ATP (P2X7) Receptors.
Int J Mol Sci
; 23(13)2022 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35806076
8.
The Novel AT2 Receptor Agonist ß-Pro7-AngIII Exerts Cardiac and Renal Anti-Fibrotic and Anti-Inflammatory Effects in High Salt-Fed Mice.
Int J Mol Sci
; 23(22)2022 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36430518
9.
The anti-fibrotic actions of relaxin are mediated through AT2 R-associated protein phosphatases via RXFP1-AT2 R functional crosstalk in human cardiac myofibroblasts.
FASEB J
; 34(6): 8217-8233, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32297670
10.
Serelaxin inhibits the profibrotic TGF-ß1/IL-1ß axis by targeting TLR-4 and the NLRP3 inflammasome in cardiac myofibroblasts.
FASEB J
; 33(12): 14717-14733, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31689135
11.
iPSC- and mesenchymoangioblast-derived mesenchymal stem cells provide greater protection against experimental chronic allergic airways disease compared with a clinically used corticosteroid.
FASEB J
; 33(5): 6402-6411, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30768365
12.
AT1R-AT2R-RXFP1 Functional Crosstalk in Myofibroblasts: Impact on the Therapeutic Targeting of Renal and Cardiac Fibrosis.
J Am Soc Nephrol
; 30(11): 2191-2207, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31511361
13.
Inflammasomes-A Molecular Link for Altered Immunoregulation and Inflammation Mediated Vascular Dysfunction in Preeclampsia.
Int J Mol Sci
; 21(4)2020 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32093005
14.
Profiling histone modifications in the normal mouse kidney and after unilateral ureteric obstruction.
Am J Physiol Renal Physiol
; 317(3): F606-F615, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31268352
15.
The efficacy of pirfenidone in a sheep model of pulmonary fibrosis.
Exp Lung Res
; 45(9-10): 310-322, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31762329
16.
The therapeutic effect of mesenchymal stem cells on pulmonary myeloid cells following neonatal hyperoxic lung injury in mice.
Respir Res
; 19(1): 114, 2018 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29884181
17.
Intranasal administration of mesenchymoangioblast-derived mesenchymal stem cells abrogates airway fibrosis and airway hyperresponsiveness associated with chronic allergic airways disease.
FASEB J
; 31(9): 4168-4178, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28626025
18.
Inhibition of the KCa3.1 Channel Alleviates Established Pulmonary Fibrosis in a Large Animal Model.
Am J Respir Cell Mol Biol
; 56(4): 539-550, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28060543
19.
Relaxin contributes to the regulation of arterial pressure in adult female mice.
Clin Sci (Lond)
; 131(23): 2795-2805, 2017 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29101299
20.
Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt-induced hypertension.
Pharmacol Res
; 116: 77-86, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27986554