Pesquisa | BVS IEC

1.

A DENV-2-type-specific monoclonal antibody binds to the DENV-complex-reactive antigenic site on envelope protein domain 3.

Sarathy, Vanessa V; Pitcher, Trevor J; Gromowski, Gregory D; Roehrig, John T; Barrett, Alan D T.

J Gen Virol ; 98(6): 1299-1304, 2017 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-28631593

2.

A lethal model of disseminated dengue virus type 1 infection in AG129 mice.

Milligan, Gregg N; Sarathy, Vanessa V; White, Mellodee M; Greenberg, M Banks; Campbell, Gerald A; Pyles, Richard B; Barrett, Alan D T; Bourne, Nigel.

J Gen Virol ; 98(10): 2507-2519, 2017 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-28949904

3.

A lethal murine infection model for dengue virus 3 in AG129 mice deficient in type I and II interferon receptors leads to systemic disease.

Sarathy, Vanessa V; White, Mellodee; Li, Li; Gorder, Summer R; Pyles, Richard B; Campbell, Gerald A; Milligan, Gregg N; Bourne, Nigel; Barrett, Alan D T.

J Virol ; 89(2): 1254-66, 2015 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-25392217

4.

Functional analysis of dengue virus (DENV) type 2 envelope protein domain 3 type-specific and DENV complex-reactive critical epitope residues.

Pitcher, Trevor J; Sarathy, Vanessa V; Matsui, Kiyohiko; Gromowski, Gregory D; Huang, Claire Y-H; Barrett, Alan D T.

J Gen Virol ; 96(Pt 2): 288-293, 2015 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-25351518

5.

Characterization of lethal dengue virus type 4 (DENV-4) TVP-376 infection in mice lacking both IFN-α/ß and IFN-Î³ receptors (AG129) and comparison with the DENV-2 AG129 mouse model.

Sarathy, Vanessa V; Infante, Ernesto; Li, Li; Campbell, Gerald A; Wang, Tian; Paessler, Slobodan; Robert Beatty, P; Harris, Eva; Milligan, Gregg N; Bourne, Nigel; Barrett, Alan D T.

J Gen Virol ; 96(10): 3035-3048, 2015 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-26296350

6.

Impact of yellow fever virus envelope protein on wild-type and vaccine epitopes and tissue tropism.

Davis, Emily H; Wang, Binbin; White, Mellodee; Huang, Yan-Jang S; Sarathy, Vanessa V; Wang, Tian; Bourne, Nigel; Higgs, Stephen; Barrett, Alan D T.

NPJ Vaccines ; 7(1): 39, 2022 Mar 23.

Artigo em Inglês | MEDLINE | ID: mdl-35322047

7.

A genetically stable Zika virus vaccine candidate protects mice against virus infection and vertical transmission.

Adam, Awadalkareem; Fontes-Garfias, Camila R; Sarathy, Vanessa V; Liu, Yang; Luo, Huanle; Davis, Emily; Li, Wenqian; Muruato, Antonio E; Wang, Binbin; Ahatov, Renat; Mahmoud, Yoseph; Shan, Chao; Osman, Samantha R; Widen, Steven G; Barrett, Alan D T; Shi, Pei-Yong; Wang, Tian.

NPJ Vaccines ; 6(1): 27, 2021 Feb 17.

Artigo em Inglês | MEDLINE | ID: mdl-33597526

8.

Ideal Criteria for Accurate Mouse Models of Vector-Borne Diseases with Emphasis on Scrub Typhus and Dengue.

Sarathy, Vanessa V; Walker, David H.

Am J Trop Med Hyg ; 103(3): 970-975, 2020 09.

Artigo em Inglês | MEDLINE | ID: mdl-32602433

9.

Finding Their Type: Elusive Antigenic Sites on Dengue Virus 3 Mapped with Human Antibodies.

Sarathy, Vanessa V; Barrett, Alan D T.

Cell Host Microbe ; 27(5): 681-682, 2020 05 13.

Artigo em Inglês | MEDLINE | ID: mdl-32407701

10.

Using Next Generation Sequencing to Study the Genetic Diversity of Candidate Live Attenuated Zika Vaccines.

Collins, Natalie D; Shan, Chao; Nunes, Bruno T D; Widen, Steven G; Shi, Pei-Yong; Barrett, Alan D T; Sarathy, Vanessa V.

Vaccines (Basel) ; 8(2)2020 Apr 03.

Artigo em Inglês | MEDLINE | ID: mdl-32260110

11.

Inter- and intra-lineage genetic diversity of wild-type Zika viruses reveals both common and distinctive nucleotide variants and clusters of genomic diversity.

Collins, Natalie D; Widen, Steven G; Li, Li; Swetnam, Daniele M; Shi, Pei-Yong; Tesh, Robert B; Sarathy, Vanessa V.

Emerg Microbes Infect ; 8(1): 1126-1138, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31355708

12.

Attenuation of Zika Virus by Passage in Human HeLa Cells.

Li, Li; Collins, Natalie D; Widen, Steven G; Davis, Emily H; Kaiser, Jaclyn A; White, Mellodee M; Greenberg, M Banks; Barrett, Alan D T; Bourne, Nigel; Sarathy, Vanessa V.

Vaccines (Basel) ; 7(3)2019 08 20.

Artigo em Inglês | MEDLINE | ID: mdl-31434319

13.

An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses.

Li, Guangyu; Adam, Awadalkareem; Luo, Huanle; Shan, Chao; Cao, Zengguo; Fontes-Garfias, Camila R; Sarathy, Vanessa V; Teleki, Cody; Winkelmann, Evandro R; Liang, Yuejin; Sun, Jiaren; Bourne, Nigel; Barrett, Alan D T; Shi, Pei-Yong; Wang, Tian.

NPJ Vaccines ; 4: 48, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31815005

14.

Current status of Severe Fever with Thrombocytopenia Syndrome vaccine development.

Reece, Lisa M; Beasley, David Wc; Milligan, Gregg N; Sarathy, Vanessa V; Barrett, Alan Dt.

Curr Opin Virol ; 29: 72-78, 2018 04.

Artigo em Inglês | MEDLINE | ID: mdl-29642053

15.

Spectrum of activity testing for therapeutics against all four dengue virus serotypes in AG129 mouse models: Proof-of-concept studies with the adenosine nucleoside inhibitor NITD-008.

Milligan, Gregg N; White, Mellodee; Zavala, Diana; Pyles, Richard B; Sarathy, Vanessa V; Barrett, Alan D T; Bourne, Nigel.

Antiviral Res ; 154: 104-109, 2018 06.

Artigo em Inglês | MEDLINE | ID: mdl-29665374

16.

Characterization of a murine model of non-lethal, symptomatic dengue virus infection.

Sarathy, Vanessa V; White, Mellodee; Li, Li; Kaiser, Jaclyn A; Campbell, Gerald A; Milligan, Gregg N; Bourne, Nigel; Barrett, Alan D T.

Sci Rep ; 8(1): 4900, 2018 03 20.

Artigo em Inglês | MEDLINE | ID: mdl-29559699

17.

Mouse models of dengue virus infection for vaccine testing.

Sarathy, Vanessa V; Milligan, Gregg N; Bourne, Nigel; Barrett, Alan D T.

Vaccine ; 33(50): 7051-60, 2015 Dec 10.

Artigo em Inglês | MEDLINE | ID: mdl-26478201

18.

A Dengue Virus Type 4 Model of Disseminated Lethal Infection in AG129 Mice.

Milligan, Gregg N; Sarathy, Vanessa V; Infante, Ernesto; Li, Li; Campbell, Gerald A; Beatty, P Robert; Harris, Eva; Barrett, Alan D T; Bourne, Nigel.

PLoS One ; 10(5): e0125476, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-25938762

19.

Using next generation sequencing to study the genetic diversity of candidate live attenuated zika vaccines

Collins, Natalie D; Shan, Chao; Nunes, Bruno Tardelli Diniz; Widen, Steven G; Shi, Pei-Yong; Barrett, Alan D. T; Sarathy, Vanessa V.

COLLINS, Natalie D. et al. Using next generation sequencing to study the genetic diversity of candidate live attenuated zika vaccines. Vaccines, v. 8, n. 2, p. 1-9, 2020.

Artigo em Inglês | Instituto Evandro Chagas (DSpace) | ID: ied-4087

20.

Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection.

Pinto, Amelia K; Brien, James D; Lam, Chia-Ying Kao; Johnson, Syd; Chiang, Cindy; Hiscott, John; Sarathy, Vanessa V; Barrett, Alan D; Shresta, Sujan; Diamond, Michael S.

mBio ; 6(5): e01316-15, 2015 Sep 15.

Artigo em Inglês | MEDLINE | ID: mdl-26374123

BVS IEC

Instituto Evandro Chagas

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