Detalhe da pesquisa
1.
The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis.
Cell
; 149(5): 1098-111, 2012 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22632973
2.
The Vitamin C Enantiomers Possess a Comparable Potency in the Induction of Oxidative Stress in Cancer Cells but Differ in Their Toxicity.
Int J Mol Sci
; 25(5)2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38473779
3.
Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1.
Mol Cell
; 58(6): 989-1000, 2015 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26051179
4.
Akt: a key transducer in cancer.
J Biomed Sci
; 29(1): 76, 2022 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36180910
5.
The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis.
Cell
; 151(4): 913-914, 2012 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30360292
6.
Formation of mammalian preribosomes proceeds from intermediate to composed state during ribosome maturation.
J Biol Chem
; 294(28): 10746-10757, 2019 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31076509
7.
A chirality-dependent action of vitamin C in suppressing Kirsten rat sarcoma mutant tumor growth by the oxidative combination: Rationale for cancer therapeutics.
Int J Cancer
; 146(10): 2822-2828, 2020 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31472018
8.
Correction: Akt: a key transducer in cancer.
J Biomed Sci
; 30(1): 7, 2023 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36698128
9.
Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
Breast Cancer Res
; 19(1): 74, 2017 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28666462
10.
High-throughput profiling of signaling networks identifies mechanism-based combination therapy to eliminate microenvironmental resistance in acute myeloid leukemia.
Haematologica
; 102(9): 1537-1548, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28659338
11.
Autoregulation of the mechanistic target of rapamycin (mTOR) complex 2 integrity is controlled by an ATP-dependent mechanism.
J Biol Chem
; 288(38): 27019-27030, 2013 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23928304
12.
Universal whole-genome Oxford nanopore sequencing of SARS-CoV-2 using tiled amplicons.
Sci Rep
; 13(1): 10334, 2023 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37365249
13.
Whole-Genome Sequencing Among Kazakhstani Children with Early-Onset Epilepsy Revealed New Gene Variants and Phenotypic Variability.
Mol Neurobiol
; 60(8): 4324-4335, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37095367
14.
The mTOR (mammalian target of rapamycin) kinase maintains integrity of mTOR complex 2.
J Biol Chem
; 286(46): 40386-94, 2011 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21965657
15.
Growing roles for the mTOR pathway.
Curr Opin Cell Biol
; 17(6): 596-603, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16226444
16.
Enhancing an Oxidative "Trojan Horse" Action of Vitamin C with Arsenic Trioxide for Effective Suppression of KRAS-Mutant Cancers: A Promising Path at the Bedside.
Cells
; 11(21)2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36359850
17.
The Oxidative Drug Combination for Suppressing KRAS G12D Inducible Tumour Growth.
Biomed Res Int
; 2022: 9426623, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36619305
18.
A high scale SARS-CoV-2 profiling by its whole-genome sequencing using Oxford Nanopore Technology in Kazakhstan.
Front Genet
; 13: 906318, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36118859
19.
Endoplasmic reticulum is a main localization site of mTORC2.
Biochem Biophys Res Commun
; 413(1): 46-52, 2011 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21867682
20.
Wheat Germination Is Dependent on Plant Target of Rapamycin Signaling.
Front Cell Dev Biol
; 8: 606685, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33330509