RESUMO
Phylogenetic analysis of 166 human parvovirus B19 sequences from 11 different countries attributed 91.57% to genotype 1, 5.42% to genotype 3b, and 3.01% to genotype 3a. Very similar viruses of genotype 1 circulated widely in Europe and Israel. Genotype 3b seems to show an increasing spread outside of Africa.
Assuntos
DNA Viral/genética , Infecções por Parvoviridae/epidemiologia , Infecções por Parvoviridae/virologia , Parvovirus B19 Humano/classificação , Parvovirus B19 Humano/genética , Filogenia , Adolescente , Adulto , África/epidemiologia , Idoso , Criança , Pré-Escolar , Análise por Conglomerados , DNA Viral/química , Europa (Continente)/epidemiologia , Feminino , Genótipo , Humanos , Lactente , Israel/epidemiologia , Masculino , Pessoa de Meia-Idade , Epidemiologia Molecular/métodos , Parvovirus B19 Humano/isolamento & purificação , Prevalência , Homologia de Sequência , Adulto JovemRESUMO
During 2005-2006, nine measles virus (MV) genotypes were identified throughout the World Health Organization European Region. All major epidemics were associated with genotypes D4, D6, and B3. Other genotypes (B2, D5, D8, D9, G2, and H1) were only found in limited numbers of cases after importation from other continents. The genetic diversity of endemic D6 strains was low; genotypes C2 and D7, circulating in Europe until recent years, were no longer identified. The transmission chains of several indigenous MV strains may thus have been interrupted by enhanced vaccination. However, multiple importations from Africa and Asia and virus introduction into highly mobile and unvaccinated communities caused a massive spread of D4 and B3 strains throughout much of the region. Thus, despite the reduction of endemic MV circulation, importation of MV from other continents caused prolonged circulation and large outbreaks after their introduction into unvaccinated and highly mobile communities.